This study aimed to isolate marine bacteria to investigate their stress response, inhibition mechanisms, and degradation processes under high-load conditions of salinity and enrofloxacin (ENR). The results demonstrated that marine bacteria exhibited efficient pollutant removal efficiency even under high ENR stress (up to 10 mg/L), with chemical oxygen demand (COD), total phosphorus (TP), total nitrogen (TN) and ENR removal efficiencies reaching approximately 88%, 83%, 61%, and 73%, respectively. The predominant families of marine bacteria were (50.46%), (32.30%), and (13.36%). They responded to ENR removal by altering cell membrane properties, stimulating the activity of xenobiotic-metabolizing enzymes and antioxidant systems, and mitigating ENR stress through the secretion of extracellular polymeric substance (EPS). The marine bacteria exhibited robust adaptability to environmental factors and effective detoxification of ENR, simultaneously removing carbon, nitrogen, phosphorus, and antibiotics from the wastewater. The attapulgite carrier enhanced the bacteria's resistance to the environment. When treating actual mariculture wastewater, the removal efficiencies of COD and TN exceeded 80%, TP removal efficiency exceeded 90%, and ENR removal efficiency approached 100%, significantly higher than reported values in similar salinity reactors. Combining the constructed physical and mathematical models of tolerant bacterial, this study will promote the practical implementation of marine bacterial-based biotechnologies in high-loading saline wastewater treatment.

中文翻译：

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基于海洋细菌和微生物载体强化降解海水养殖废水中恩诺沙星


本研究旨在分离海洋细菌，研究其在盐度和恩诺沙星（ENR）高负荷条件下的应激反应、抑制机制和降解过程。结果表明，即使在高ENR胁迫下（高达10 mg/L），海洋细菌也表现出高效的污染物去除效率，化学需氧量（COD）、总磷（TP）、总氮（TN）和ENR去除效率达到约分别为 88%、83%、61% 和 73%。海洋细菌的主要家族为（50.46%）、（32.30%）和（13.36%）。他们通过改变细胞膜特性、刺激外源代谢酶和抗氧化系统的活性以及通过分泌细胞外聚合物（EPS）减轻 ENR 应激来响应 ENR 去除。海洋细菌表现出对环境因素的强大适应性和ENR的有效解毒作用，同时去除废水中的碳、氮、磷和抗生素。凹凸棒石载体增强了细菌对环境的抵抗力。处理实际海水养殖废水时，COD、TN去除率超过80%，TP去除率超过90%，ENR去除率接近100%，显着高于同类盐度反应器的报道值。结合所构建的耐受细菌的物理和数学模型，本研究将促进基于海洋细菌的生物技术在高负荷含盐废水处理中的实际应用。