Antithrombotic Treatment for Cervical Artery Dissection: A Systematic Review and Individual Patient Data Meta-Analysis.,JAMA Neurology

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Antithrombotic Treatment for Cervical Artery Dissection: A Systematic Review and Individual Patient Data Meta-Analysis.
JAMA Neurology ( IF 29.0 ) Pub Date : 2024-05-13 , DOI: 10.1001/jamaneurol.2024.1141
Josefin E. Kaufmann _{1,

2} , Eric L. Harshfield ₃ , Henrik Gensicke _{1,

2} , Susanne Wegener ₄ , Patrik Michel ₅ , Georg Kägi _{6,

7} , Krassen Nedeltchev ₈ , Lars Kellert _{9,

10} , Sverre Rosenbaum ₁₁ , Christian H. Nolte _{12,

13} , Hanne Christensen ₁₁ , Marcel Arnold ₆ , Philippe Lyrer ₁ , Christopher Levi ₁₄ , Philip M. Bath ₁₅ , Stefan T. Engelter _{1,

2} , Christopher Traenka _{1,

2} , Hugh S. Markus ₃ , Mohd Nor Azlisham ₁₆ , Rose Boswell ₁₆ , Neil Baldwin ₁₆ , Anthoy Rudd ₁₆ , Isle Burger ₁₆ , Lalit Kalra ₁₆ , Ahamed Hassan ₁₆ , Christopher Price ₁₆ , Anand Dixit ₁₆ , Ronald MacWalter ₁₆ , David Cohen ₁₆ , Richard Davey ₁₆ , Tim Cassidy ₁₆ , Gunarathnam Gunathilagan ₁₆ , Damian Jenkinson ₁₆ , Frances Harrington ₁₆ , Martin James ₁₆ , Graham Venables ₁₆ , Nigel Smyth ₁₆ , Hedley Emsley ₁₆ , Louise Shaw ₁₆ , Joanna Lovett ₁₆ , Paul Guyler ₁₆ , Hugh S Markus ₁₆ , Patrick Gompertz ₁₆ , Debs Kelly ₁₆ , Isam Salih ₁₆ , Brendan Davies ₁₆ , Hamsaraj Shetty ₁₆ , Amit Mistri ₁₆ , David Hargrovers ₁₆ , Khalid Rashed ₁₆ , Brian Clarke ₁₆ , David Collas ₁₆ , Bridget Colam ₁₆ , Rustam Al-Shahi Salman ₁₆ , Richard Gerraty ₁₆ , Jon Sturm ₁₆ , Christopher Levi ₁₆ , Tim Kleinig ₁₆ , Andrew Wrong ₁₆ , Peter Hand ₁₆ , Candice Delcourt ₁₆ , Alice King ₁₆ , Jeremy Madigan ₁₆ , Atkinson Morley ₁₆ , John Norris ₁₆ , Jennifer Peycke ₁₆ , Melina Wilson ₁₆ , Cara Hicks ₁₆ , Elizabeth Hayter ₁₆ , Ranjit Menon ₁₆ , Fiona Kennedy ₁₆ , Usman Khan ₁₆ , Adina Feldman ₁₆ , Matt Hollocks ₁₆ , Graham S Venebales ₁₆ , Sally Kerry ₁₆ , Ahames Hassan ₁₆ , Gary A Ford ₁₆ , Philip M Bath ₁₆ , Chris Weir ₁₆ , Deniy Briley ₁₆ , Ajay Bhalla ₁₆ , Stefan Engelter ₁₆ , Christopher Traenka ₁₆ , Sabine Schaedelin ₁₆ , Philippe Lyrer ₁₆ , M Kloss ₁₆ , D Droste ₁₆ , T Brandt ₁₆ , MN Psychogius ₁₆ , A Brehm ₁₆ , A Grau ₁₆ , P Sandor ₁₆ , S von Felten ₁₆ , A Hammann ₁₆ , Thomas Fabbro ₁₆ , Martina Maurer ₁₆ , Klaus Ehrlich ₁₆ , Astrid Rösler ₁₆ , P Forst ₁₆ , Timo Kahles ₁₆ , Krassen Nedeltchev ₁₆ , Valerian Altersberger ₁₆ , Leo Bonati ₁₆ , Alexander Brehm ₁₆ , N Bruni ₁₆ , Gian-Marco de Marchis ₁₆ , Urs Fisch ₁₆ , Joachim Fladt ₁₆ , Henrik Gensicke ₁₆ , Lisa Hert ₁₆ , Nils Peters ₁₆ , Alexandros Polymeris ₁₆ , C Stippich ₁₆ , Sebastian Thilemann ₁₆ , Benjamin Wagner ₁₆ , Marcel Arnold ₁₆ , Urs Fischer ₁₆ , MR Heldner ₁₆ , David J Seiffge ₁₆ , L Sveikata ₁₆ , R Sztajzel ₁₆ , H Muller ₁₆ , P Correia ₁₆ , A Eskandari ₁₆ , I Meyer ₁₆ , Patrik Michel ₁₆ , S Nannoni ₁₆ , S Remillard ₁₆ , G Sirimarco ₁₆ , A Zachariadis ₁₆ , Georg Kaegi ₁₆ , A Mueller ₁₆ , Jochen Vehoff ₁₆ , J Hamann ₁₆ , Andreas Luft ₁₆ , L Steiner ₁₆ , Susanne Wegener ₁₆ , JH Erdur ₁₆ , Christian Nolte ₁₆ , R v. Rennenberg ₁₆ , JF Scheitz ₁₆ , K Fell ₁₆ , L Kellert ₁₆ , Hanne Christensen ₁₆ , S Rosenbaum ₁₆ ,

Affiliation

Department of Neurology and Stroke Center, University Hospital Basel and University of Basel, Switzerland
Neurology and Neurorehabilitation, University Department of Geriatric Medicine FELIX PLATTER, University of Basel, Basel, Switzerland
Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom
Division of Vascular Neurology and Neurorehabilitation, Department of Neurology, University Hospital of Zurich, and University of Zurich, Switzerland
Stroke Center and Neurology Service, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Department of Neurology, University Hospital Bern, University of Bern, Bern, Switzerland
Department of Neurology and Stroke Center, Cantonal Hospital St Gallen, St Gallen, Switzerland
Department of Neurology and Stroke Center, Cantonal Hospital Aarau, Aarau, Switzerland
Department of Neurology, Ludwig Maximilian University, Munich, Germany
Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany
Department of Neurology, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark
Department of Neurology with Experimental Neurology, Center for Stroke Research Berlin, Charite-Universitätsmedizin Berlin, Berlin, Germany
Berlin Institute of Healths at Charite, Charite-Universitätsmedizin Berlin, Berlin, Germany
Faculty of Health and Medicine, University of Newcastle, and John Hunter Hospital, Newcastle, Australia
Stroke Trials Unit, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, United Kingdom
for the CADISS and TREAT-CAD Investigators

Cervical artery dissection is the most common cause of stroke in younger adults. To date, there is no conclusive evidence on which antithrombotic therapy should be used to treat patients.

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