AimsWe examined the effectiveness of a novel cardiopulmonary management wearable sensor (worn for less than 5 mins) at measuring congestion and correlated the device findings with established clinical measures of congestion.Methods and resultsWe enrolled three cohorts of patients: (1) patients with heart failure (HF) receiving intravenous diuretics in hospital; (2) patients established on haemodialysis, and (3) HF patients undergoing right heart catheterization (RHC). The primary outcomes in the respective cohorts were a Spearman correlation between (1) change in weight and change in thoracic impedance (TI) (from enrolment, 24 h after admission to discharge) in patients hospitalized for HF; (2) lung ultrasound B‐lines and volume removed during dialysis with device measured TI, and (3) pulmonary capillary wedge pressure (PCWP) and sub‐acoustic diastolic, third heart sound (S3) in the patients undergoing RHC. A total of 66 patients were enrolled. In HF patients (n = 25), change in weight was correlated with both change in device TI (Spearman correlation [rsp] = −0.64, p = 0.002) and change in device S3 (rsp = −0.53, p = 0.014). In the haemodialysis cohort (n = 21), B‐lines and TI were strongly correlated before (rsp = −0.71, p < 0.001) and after (rsp = −0.77, p < 0.001) dialysis. Volume of fluid removed by dialysis was correlated with change in device TI (rsp = 0.49, p = 0.024). In the RHC cohort (n = 20), PCWP measured at one time point and device S3 were not significantly correlated (rsp = 0.230, p = 0.204). There were no device‐related adverse events.ConclusionsA non‐invasive device was able to detect changes in congestion in patients with HF receiving decongestion therapy and patients having fluid removed at haemodialysis. The cardiopulmonary management device, which measures multiple parameters, is a potentially useful tool to monitor patients with HF to prevent hospitalizations.

中文翻译：

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使用非侵入性监测设备测量心力衰竭和血液透析中的充血情况：CONGEST-HF

目的我们检查了新型心肺管理可穿戴传感器（佩戴时间不超过 5 分钟）在测量充血方面的有效性，并将设备结果与既定的临床充血测量方法相关联。方法和结果我们招募了三组患者：(1) 心力衰竭患者(HF) 在医院接受静脉利尿剂； (2) 进行血液透析的患者，以及 (3) 接受右心导管插入术 (RHC) 的心衰患者。各队列的主要结果是以下因素之间的 Spearman 相关性：(1) 因心力衰竭住院的患者的体重变化和胸阻抗 (TI) 变化（从入组、入院后 24 小时到出院）； (2) 肺超声 B 线和透析期间使用设备测量 TI 去除的体积，以及 (3) 接受 RHC 的患者的肺毛细血管楔压 (PCWP) 和亚声舒张第三心音 (S3)。共有 66 名患者入组。在心力衰竭患者中（n= 25），体重变化与设备 TI 的变化相关（Spearman 相关性 [rsp] = -0.64，p= 0.002) 并更改设备 S3 (rsp=-0.53，p= 0.014）。在血液透析队列中（n= 21), B 线和 TI 之前有很强的相关性 (rsp=−0.71，p< 0.001) 和之后 (rsp=−0.77，p< 0.001) 透析。透析去除的液体量与装置 TI 的变化相关（rsp= 0.49，p= 0.024）。在 RHC 队列中（n= 20），某一时间点测量的 PCWP 与设备 S3 不显着相关（rsp= 0.230,p= 0.204）。没有发生与设备相关的不良事件。结论非侵入性设备能够检测接受减充血治疗的心力衰竭患者和在血液透析中去除液体的患者的充血变化。心肺管理设备可测量多个参数，是监测心力衰竭患者以防止住院的潜在有用工具。