An unconventional [1 + 1 + 1 + 1 + 1 + 1] annulation process was developed for the construction of β,β-dithioketones by merging C–C and C–S bond cleavage. In this reaction, rongalite concurrently served as triple C1 units, dual sulfur(II) synthons, and a reductant for the first time. Mechanism investigation indicated that the reaction involved the self-mediated valence state change of rongalite. By performing this step-economical method, the challenging construction of C₅-substituted 1,3-dithiane can be achieved under mild and simple conditions.

中文翻译：

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通过合并 [1 + 1 + 1 + 1 + 1 + 1] 环化中的 C–C 和 C–S 键断裂合成 β,β-二硫酮


开发了一种非常规的[1 + 1 + 1 + 1 + 1 + 1]成环工艺，通过合并C-C和C-S键断裂来构建β,β-二硫酮。在此反应中，雕白粉首次同时充当三C1单元、双硫(II)合成子和还原剂。机理研究表明该反应涉及雕白粉自介导的价态变化。通过这种经济的步骤，可以在温和且简单的条件下实现具有挑战性的C ₅ -取代的1,3-二噻烷的构建。