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Correction to “Improving Cancer Chemoradiotherapy Treatment by Dual Controlled Release of Wortmannin and Docetaxel in Polymeric Nanoparticles”
ACS Nano ( IF 17.1 ) Pub Date : 2024-05-14 , DOI: 10.1021/acsnano.4c05756
Kin Man Au , Yuanzeng Min , Xi Tian , Longzhen Zhang , Virginia Perello , Joseph M. Caster , Andrew Z. Wang

In the originally published version of the article, the histological images in main text Figures 9, 10, and 11 and Supporting Information Figures S8 and S9 were wrongly assembled. After reviewing the data, we would like to make the following 5 corrections: On Figure 9, the CD31-stained histological images recorded for tumor treated with Dtxl NPs (H460 tumor with XRT), Wtmn NPs (H460 tumor with XRT), and Dtxl NPs (PC3 with XRT) were wrongly assembled. The correct Figure 9 should be as follows: On Figure 10, the DAPI channel of the tumor treated with Dtxl NPs + Wtmn NPs (PC3) was miss-pasted as the immunofluorescence image of the PBS control group (PBS, PC3) stained with anti-H2AX. The correct immunofluorescence image should be as follows: On Figure 11, the immunofluorescence image recorded Wtmn NPs (PC3 tumor) was incorrectly pasted twice in the neighboring Dtxl NPs + Wtmn NPs group. We corrected the immunofluorescence image recorded for the tumor treated with Dtxl NPs + Wtmn NPs as follows: On Figure S8, the H&E-stained tumor sections recorded for the Dtxl NPs + Wtmn NPs (H460), PBS with XRT (H460), and PBS with XRT (PC3 tumor) groups were misassembled. We were just aware of this mistake. The correct figure should be as follows: On Figure S9, 3 Masson’s trichrome-stained tumor sections recorded for the Dtxl NPs + Wtmn NPs (PC3, no irradiation), Dtxl NPs (PC3, with 5 Gy XRT), and Dtxl NPs + Wtmn NPs (PC3, with 5 Gy XRT) were wrongly assembled. We were just aware of this mistake. The correct figure should be as follows: In all histological studies, we recorded histological images of more than one tumor for all control and treatment groups. The erratum does not affect any of the experimental results, discussions, or conclusions reported in the paper. The authors sincerely apologize for this unintended oversight. Steps have been taken to prevent similar problems from occurring in the future. This article has not yet been cited by other publications.

中文翻译:


对“通过聚合物纳米颗粒中渥曼青霉素和多西紫杉醇双重控释来改善癌症放化疗治疗”的更正



在该文章最初发表的版本中,正文图 9、图 10 和图 11 以及支持信息图 S8 和 S9 中的组织学图像组装错误。在审查数据后,我们希望进行以下 5 项修正: 图 9 中记录了用 Dtxl NP(使用 XRT 的 H460 肿瘤)、Wtmn NP(使用 XRT 的 H460 肿瘤)和 Dtxl 治疗的肿瘤的 CD31 染色组织学图像NP(带 XRT 的 PC3)组装错误。正确的图9应该是这样的: 图10中,Dtxl NPs + Wtmn NPs (PC3)治疗肿瘤的DAPI通道被误贴为PBS对照组的免疫荧光图像( PBS、PC3)用抗-H2AX染色。正确的免疫荧光图像应如下:在图11中,记录Wtmn NP(PC3肿瘤)的免疫荧光图像在相邻的Dtxl NP + Wtmn NP组中错误地粘贴了两次。我们校正了用 Dtxl NP + Wtmn NP 处理的肿瘤记录的免疫荧光图像,如下: 在图 S8 上,为 Dtxl NP + Wtmn NP (H460)、PBS 记录的 H&E 染色肿瘤切片XRT (H460) 和 PBS with XRT (PC3 肿瘤) 组组装错误。我们刚刚意识到这个错误。正确的数字应如下: 在图S9中,记录了3张Masson三色染色的肿瘤切片,分别为Dtxl NP + Wtmn NP(PC3,无照射)、Dtxl NP(PC3,使用5 Gy XRT) ),并且 Dtxl NP + Wtmn NP(PC3,使用 5 Gy XRT)组装错误。我们刚刚意识到这个错误。正确的数字应如下: 在所有组织学研究中,我们为所有对照组和治疗组记录了不止一种肿瘤的组织学图像。 勘误不影响论文中报告的任何实验结果、讨论或结论。作者对这一无意的疏忽表示诚挚的歉意。已采取措施防止今后发生类似问题。这篇文章尚未被其他出版物引用。
更新日期:2024-05-14
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