Hyperplastic scars, especially keloids, have posed a significant clinical challenge due to their high recurrence rate. Compression therapy, a cost‐effective treatment, has demonstrated efficacy in reducing scarring and preventing recurrence. However, the compression methods exhibit limitations in adapting to the complex contours and accurately adjusting the treatment pressure, resulting in unsatisfactory treatment effects. In this study, silicone is chosen as the substrate layer ink, while the conductive ink is developed by incorporating nano‐carbon black into the polymer composite. These are printed alternately within the supported gels to construct an integrated orthotic device with precise pressure control capabilities and complex structures. Results demonstrated the printed orthosis displayed excellent mechanical properties, durability and biocompatibility. It can successfully detect various stress changes with short response times. The utilization of finite element analysis aided in the design of personalized orthosis to achieve optimal pressure for scar treatment. Finally, orthosis‐mediated pressure treatment is performed on rat tail scar models. By monitoring resistance value, it can be inferred whether the treatment pressure applied by orthosis fell within an optimal range. Overall, personalized piezoresistive anti‐scar orthoses offer an accurate and effective treatment method for scar. This innovative approach presents a novel strategy in the realm of personalized scar management.

中文翻译：

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基于嵌入式3D打印的具有精确压力监测功能的个性化压阻式防疤痕矫形器


增生性疤痕，尤其是疤痕疙瘩，由于其高复发率而给临床带来了重大挑战。压迫疗法是一种经济有效的治疗方法，已被证明可以有效减少疤痕和预防复发。然而，加压方法在适应复杂轮廓和精确调节治疗压力方面存在局限性，导致治疗效果不理想。在这项研究中，选择有机硅作为基材层墨水，而导电墨水是通过将纳米炭黑掺入聚合物复合材料中而开发的。这些在支撑凝胶内交替打印，以构建具有精确压力控制能力和复杂结构的集成矫形装置。结果表明，打印的矫形器表现出优异的机械性能、耐用性和生物相容性。它可以成功检测各种压力变化，响应时间短。有限元分析的利用有助于个性化矫形器的设计，以实现疤痕治疗的最佳压力。最后，对大鼠尾部疤痕模型进行矫形器介导的压力治疗。通过监测阻力值，可以推断矫形器施加的治疗压力是否落在最佳范围内。总体而言，个性化压阻抗疤痕矫形器为疤痕治疗提供了一种准确有效的方法。这种创新方法在个性化疤痕管理领域提出了一种新颖的策略。