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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
Cell ( IF 64.5 ) Pub Date : 2024-05-15 , DOI: 10.1016/j.cell.2024.04.025 Matthew B. Maxwell , Marianne S. Hom-Tedla , Jawoon Yi , Shitian Li , Samuel A. Rivera , Jingting Yu , Mannix J. Burns , Helen M. McRae , Braden T. Stevenson , Katherine E. Coakley , Josephine Ho , Kameneff Bojorquez Gastelum , Joshua C. Bell , Alexander C. Jones , Ramez N. Eskander , Emily C. Dykhuizen , Gerald S. Shadel , Susan M. Kaech , Diana C. Hargreaves
Cell ( IF 64.5 ) Pub Date : 2024-05-15 , DOI: 10.1016/j.cell.2024.04.025 Matthew B. Maxwell , Marianne S. Hom-Tedla , Jawoon Yi , Shitian Li , Samuel A. Rivera , Jingting Yu , Mannix J. Burns , Helen M. McRae , Braden T. Stevenson , Katherine E. Coakley , Josephine Ho , Kameneff Bojorquez Gastelum , Joshua C. Bell , Alexander C. Jones , Ramez N. Eskander , Emily C. Dykhuizen , Gerald S. Shadel , Susan M. Kaech , Diana C. Hargreaves
Clinical trials have identified ARID1A mutations as enriched among patients who respond favorably to immune checkpoint blockade (ICB) in several solid…
中文翻译：
ARID1A 抑制 R 环介导的 STING I 型干扰素通路激活抗肿瘤免疫
临床试验已发现 ARID1A 突变在几种实体瘤中对免疫检查点阻断 (ICB) 产生良好反应的患者中大量存在……
更新日期：2024-05-15
中文翻译：
ARID1A 抑制 R 环介导的 STING I 型干扰素通路激活抗肿瘤免疫
临床试验已发现 ARID1A 突变在几种实体瘤中对免疫检查点阻断 (ICB) 产生良好反应的患者中大量存在……
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