Abstract
With the advantages of a large field of view, portability, and cost-effectiveness, lensless imaging has been applied widely nowadays. However, as a powerful tool for complete polarimetric characterization of microstructural and optical properties of a medium, Mueller matrix imaging has not yet been integrated in lensless imaging scheme. Here we propose a lensless inline polarization holographic system for high-speed and high-resolution Mueller matrix imaging. Liquid crystal variable retarders are introduced to realize high-speed response and avoid vibrations and positioning errors. We apply the blind deconvolution for depolarized imaging reconstruction and the back-propagation approach for polarization hologram reconstruction, respectively. The polarimetric imaging ability and resolution performance of the proposed technique are demonstrated. Furthermore, Mueller matrix images and certain quantitative polarimetric parameters of biological samples are calculated. The proposed method can be easily implemented and integrated in various lensless imaging techniques for on-chip polarimetric imaging.
Similar content being viewed by others
Data availability
The data that support the findings of this study are available from the corresponding author upon reasonable request.
References
Pezzaniti, J.L., Chipman, R.A.: Mueller matrix imaging polarimetry. Opt. Eng. 34, 1558–1568 (1995)
Ghosh, N., Vitkin, I.A.: Tissue polarimetry: concepts, challenges, applications, and outlook. J. Biomed. Opt. 16, 110801 (2011)
Ahmad, I., Ahmad, M., Khan, K., Ashraf, S., Ahmad, S., Ikrama, M.: Ex vivo characterization of normal and adenocarcinoma colon samples by Mueller matrix polarimetry. J. Biomed. Opt. 20, 056012 (2015)
Qi, J., Elson, D.S.: Mueller polarimetric imaging for surgical and diagnostic applications: a review. J. Biophoton. 10, 950–981 (2017)
Wang, Y., He, H., Chang, J., He, C., Liu, S., Li, M., Zeng, N., Wu, J., Ma, H.: Mueller matrix microscope: a quantitative tool to facilitate detections and fibrosis scorings of liver cirrhosis and cancer tissues. J. Biomed. Opt. 21, 071112 (2016)
He, H., Liao, R., Zeng, N., Li, P., Chen, Z., Liu, X., Ma, H.: Mueller matrix polarimetry - an emerging new tool for characterizing the microstructural feature of complex biological specimen. J. Lightwave Technol. 37, 2534–2548 (2019)
Arteaga, O., Baldrís, M., Antó, J., Canillas, A., Pascual, E., Bertran, E.: Mueller matrix microscope with a dual continuous rotating compensator setup and digital demodulation. Appl. Opt. 53, 2236–2245 (2014)
Wang, Y., He, H., Chang, J., Zeng, N., Liu, S., Li, M., Ma, H.: Differentiating characteristic microstructural features of cancerous tissues using Mueller matrix microscope. Micron 79, 8–15 (2015)
Gladish, J.C., Duncan, D.D.: Liquid crystal-based Mueller matrix spectral imaging polarimetry for parameterizing mineral structural organization. Appl. Opt. 56(3), 626–635 (2017)
Laude-Boulesteix, B., Martino, A.D., Drevillon, B., Schwartz, L.: Mueller polarimetric imaging system with liquid crystals. Appl. Opt. 43, 2824–2832 (2004)
Han, C.Y., Du, C.Y., Jhou, J.Y.: Rapid full Mueller matrix imaging polarimetry based on the hybrid phase modulation technique. Opt. Commun. 382, 501–508 (2017)
Aas, L.M.S., Ellingsen, P.G., Kildemo, M.: Near infra-red Mueller matrix imaging system and application to retardance imaging of strain. Thin Solid Films 519, 2737–2741 (2011)
Twietmeyer, K.M., Chipman, R.A., Elsner, A.E., Zhao, Y., VanNasdale, D.: Mueller matrix retinal imager with optimized polarization conditions. Opt. Express 16, 21339–21354 (2008)
Chironi, E., Iemmi, C.: Mueller matrix polarimeter based on twisted nematic liquid crystal devices. Appl. Opt. 59, 8098–8105 (2020)
Han, C., Pang, S., Bower, D.V., Yiu, P., Yang, C.: Wide field-of-view on-chip Talbot fluorescence microscopy for longitudinal cell culture monitoring from within the incubator. Anal. Chem. 85, 2356–2360 (2013)
Lee, S.A., Ou, X., Lee, J.E., Yang, C.: Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor. Opt. Lett. 38, 1817–1819 (2013)
Liu, X., Yang, Y., Han, L., Guo, C.S.: Fiber-based lensless polarization holography for measuring Jones matrix parameters of polarization-sensitive materials. Opt. Express 25, 7288–7299 (2017)
Zhang, Y., Lee, S.Y., Zhang, Y., Furst, D., Fitzgerald, J., Ozcan, A.: Wide-field imaging of birefringent synovial fluid crystals using lens-free polarized microscopy for gout diagnosis. Sci. Rep. 6, 28793 (2016)
Oh, C., Isikman, S.O., Khademhosseinieh, B., Ozcan, A.: On-chip differential interference contrast microscopy using lensless digital holography. Opt. Express 25, 4717–4726 (2010)
Mudanyali, O., Tseng, D., Oh, C., Isikman, S.O., Sencan, I., Bishara, W., Oztoprak, C., Seo, S., Khademhosseini, B., Ozcan, A.: Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications. Lab Chip 10, 1417–1428 (2010)
Zhou, Y., Xiong, B., Li, X., Dai, Q., Cao, X.: Lensless imaging of plant samples using the cross-polarized light. Opt. Express 28, 31611–31623 (2020)
Ozcan, A., McLeod, E.: Lensless imaging and sensing. Annu. Rev. Biomed. Eng. 18, 77–102 (2016)
Xiao, X., Voelz, D.G.: Liquid crystal variable retarder modeling of incident angle response with experimental verification. Opt. Eng. 47, 054002 (2008)
Zhang, J., Sun, J., Chen, Q., Zuo, C.: Resolution analysis in a lens-free on-chip digital holographic microscope. IEEE Trans. Comput. Imaging 6, 697–710 (2020)
Abbasian, V., Moradi, A.-R.: Microsphere-assisted super-resolved Mueller matrix microscopy. Opt. Lett. 45, 4336–4339 (2020)
Peinado, A., Lizana, N., Vidal, J., Iemmi, C., Campos, J.: Optimization and performance criteria of a Stokes polarimeter based on two variable retarders. Opt. Express 18, 9815–9830 (2010)
Bueno, J.M.: Polarimetry using liquid-crystal variable retarders: theory and calibration. J. Opt. A Pure Appl. Opt. 2, 216–222 (2000)
Goodman, J.W.: Introduction to Fourier Optics, 2nd edn., p. 55. McGRAW-HILL, New York (1996)
Weidling, J., Isikman, S.O., Greenbaum, A., Ozcan, A., Botvinick, E.: Lens-free computational imaging of capillary morphogenesis within three-dimensional substrates. J. Biomed. Opt. 17, 126018 (2012)
Du, E., He, H., Zeng, N., Liu, C., Guo, Y., Liao, R., Sun, M., He, Y., Ma, H.: Characteristic features of mueller matrix patterns for polarization scattering model of biological tissues. J. Innov. Opt. Health Sci. 7(1), 1350028 (2014)
Neifeld, M.A.: Information, resolution, and space–bandwidth product. J. Opt. Lett. 18, 1477–1479 (1998)
Park, J., Brady, D.J., Zheng, G., Tian, L., Gao, L.: Review of bio-optical imaging systems with a high space-bandwidth product. Adv. Photonics 3, 044001 (2021)
Denis, L., Fournier, C., Fournel, T., Ducottet, C.: Twin-image noise reduction by phase retrieval in in-line digital holography. In: Papadakis, M., Laine, A.F., Unser, M.A. (eds.) SPIE’s Symposium on Optical Science and Technology, p. 59140J. Springer (2005)
Zhang, W., Cao, L., Brady, D.J., Zhang, H., Cang, J., Zhang, H., Jin, G.: Twin-image-free holography: a compressive sensing approach. Phys. Rev. Lett. 121, 093902 (2018)
Lu, S.-Y., Chipman, R.A.: Interpretation of Mueller matrices based on polar decomposition. J. Opt. Soc. Am. 13, 1106–1113 (1996)
He, H., Chang, J., He, C., Ma, H.: Transformation of full 4 × 4 Mueller matrices: a quantitative technique for biomedical diagnosis. Proc SPIE Dyn. Fluct. Biomed. Photonics 11, 970 (2016)
Acknowledgements
This work was supported by the Fundamental Research Funds for the Central Universities of China (JD2019JGPY0020) and the Key industrialization projects of Intelligent Manufacturing Institute, Hefei University of Technology (IMICZ2019001).
Author information
Authors and Affiliations
Contributions
All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by YF, WL and JL. The first draft of the manuscript was written by YF. JH is responsible for reviewing, editing and funding acquisition. All authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
Corresponding author
Ethics declarations
Conflict of interest
The authors declare no conflict of interest.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Fang, Y., Li, W., Li, J. et al. Lensless inline holographic Mueller matrix imaging. Opt Rev 30, 606–616 (2023). https://doi.org/10.1007/s10043-023-00843-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10043-023-00843-7