Sustainability and greenness are the concepts of growing interest in the area of research as well as industries. One of the frequently encountered challenges faced in research and industrial fields is the solubility of the hydrophobic compound. Conventionally organic solvents are used in various applications; however, their contribution to environmental pollution, the huge energy requirement for separation and higher consumption lead to unsustainable practice. We require solvents that curtail the usage of hazardous material, increase the competency of mass and energy and embrace the concept of recyclability or renewability. Hydrotropy is one of the approaches for fulfilling these requirements. The phenomenon of solubilizing hydrophobic compound using hydrotrope is termed hydrotropy. Researchers of various fields are attracted to hydrotropy due to its unique physicochemical properties. In this review article, fundamentals about hydrotropes and various mechanisms involved in hydrotropy have been discussed. Hydrotropes are widely used in separation, heterogeneous chemical reactions, natural product extraction and pharmaceuticals. Applications of hydrotropes in these fields are discussed at length. We have examined the significant outcomes and correlated them with green engineering and green chemistry principles, which could give an overall picture of hydrotropy as a green and sustainable approach for the above applications.

中文翻译：

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助水助长领域的进展：机理、应用和绿色概念

可持续性和绿色是研究领域和工业领域越来越感兴趣的概念。在研究和工业领域中经常遇到的挑战之一是疏水化合物的溶解度。传统上，有机溶剂用于各种应用；然而，它们对环境污染的贡献、分离所需的巨大能量和更高的消耗导致不可持续的做法。我们需要溶剂来减少有害材料的使用，提高质量和能源的能力，并接受可回收或可再生的概念。水溶助长是满足这些要求的方法之一。使用水溶助长剂溶解疏水化合物的现象称为水溶助长。由于其独特的物理化学性质，水溶助长作用吸引了各个领域的研究人员。在这篇评论文章中，讨论了水溶助长剂的基本原理和涉及水溶助长剂的各种机制。水溶助长剂广泛用于分离、非均相化学反应、天然产物提取和制药。详细讨论了水溶助长剂在这些领域的应用。我们研究了这些重要成果，并将它们与绿色工程和绿色化学原理相关联，这可以全面了解水溶助长剂作为上述应用的绿色和可持续方法。异构化学反应、天然产物提取和药物。详细讨论了水溶助长剂在这些领域的应用。我们研究了这些重要成果，并将它们与绿色工程和绿色化学原理相关联，这可以全面了解水溶助长剂作为上述应用的绿色和可持续方法。异构化学反应、天然产物提取和药物。详细讨论了水溶助长剂在这些领域的应用。我们研究了这些重要成果，并将它们与绿色工程和绿色化学原理相关联，这可以全面了解水溶助长剂作为上述应用的绿色和可持续方法。