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Long-Term Course of Remission and Recovery in Psychotic Disorders Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-15 Sara Tramazzo, Wenxuan Lian, Olesya Ajnakina, Gabrielle Carlson, Evelyn Bromet, Roman Kotov, Katherine Jonas
Objective: Understanding prognosis is critical to anticipating public health needs and providing care to individuals with psychotic disorders. However, the long-term course of remission and recovery remains unclear. In this study, the most common trajectories of illness course are described for a cohort of individuals followed for 25 years since first admission for psychosis. Methods: Participants
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Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-15 JooEun Kang, Victor M. Castro, Michael Ripperger, Sanan Venkatesh, David Burstein, Richard Karlsson Linnér, Daniel B. Rocha, Yirui Hu, Drew Wilimitis, Theodore Morley, Lide Han, Rachel Youngjung Kim, Yen-Chen Anne Feng, Tian Ge, Stephan Heckers, Georgios Voloudakis, Christopher Chabris, Panos Roussos, Thomas H McCoy, Colin G. Walsh, Roy H. Perlis, Douglas M. Ruderfer
Objective: Treatment-resistant depression (TRD) occurs in roughly one-third of all individuals with major depressive disorder (MDD). Although research has suggested a significant common variant genetic component of liability to TRD, with heritability estimated at 8% when compared with non-treatment-resistant MDD, no replicated genetic loci have been identified, and the genetic architecture of TRD remains
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“And Bomb or no Bomb, We, We Will Get to Rome”: In The Margins of Two Sessions with Lulu J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-13 Giuseppe Civitarese
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Discussion of Matthew Shaw’s “Lulu” J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-13 Peter Goldberg
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Psychoanalysis—More Than a Profession: Presidential Address, American Psychoanalytic Association, New York, February 3, 2023 J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-13 William C. Glover
This plenary address was delivered just before learning the successful outcome of a bylaw amendment extending full American Psychoanalytic Association (APsA) membership to psychoanalytic psychotherapists, researchers, scholars, and all who share a commitment to psychoanalysis. This historic change culminated efforts over the previous four decades to rectify exclusionary harms and revitalize psychoanalysis
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Narrative Capacity J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-13 Gregory Scott Rizzolo
What develops in adulthood? More specifically, what develops in adult analysis, not just in terms of thwarted childhood capacities, not just through accrued experience, but even more fundamentally in terms of abilities or structures not possible until the present moment? In this paper, I posit narrative capacity—the capacity to organize conflictual aspects of self and other in a temporary causal-motivational
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BOMBA: Adolescence, Analysis, and Moments of Resonance J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-11 Matthew F. Shaw
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Receptivity to the Weight and Heft of the Natural World in our Inner Selves J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-11 Lindsay L. Clarkson, Shelley Rockwell
Through the literary explorations and poetry of Alice Oswald, and through analysis of detailed clinical material from a Kleinian perspective, the authors expand the bounds of reverie as it is usually construed in psychoanalytic consulting rooms. The authors draw attention to the presence of a relationship to the more-than-human world as an integral aspect of our internal experience, and to the value
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Property, Materiality, Proximity: The Analytic Frame and In-Person Work J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-11 Mitchell Wilson
In-person meeting offers psychologically usable material—signifiers that serve as day’s residue—that cannot be duplicated or substituted for in remote ways of working. Questions of materiality, the history and specificity of location, and bodily proximity all are key aspects of the psychoanalytic frame, as Bleger’s classic formulations attest. The COVID-19 pandemic has changed the choreography of engagement
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The Risk of the Revelatory State J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-11 Lucinda Ballantyne
Patients enter states that in their spontaneity and deep interiority have qualities of the revelatory. I propose we recognize such a state as a clinical event: The person is in a state of intense internal receiving of self. We might think of it as a state of internal communication happening as the person speaks. The person feels real to herself. Her relation to her mind in this revelatory moment is
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The Operators Model of Psychoanalytic Clinical Reasoning J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-11 Niccolò Fiorentino Polipo, Jochem Willemsen, Delphine Kallai
In this paper, the authors develop a model of psychoanalytic clinical reasoning as the inferential process by which analytic therapists are able to arrive at an understanding of the clinical material. Starting from Bion’s theory of functions, the authors propose that a “function” can be thought of as a condition-action sequence that analytic therapists implicitly use to respond to certain configurations
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The Oedipal Virtual Citadel: Varieties of Isolation, Oedipal Conflict, and Cover-Up J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-11 Steven H. Cooper
The author elaborates some of the fantasies and defenses that protect some patients in their oedipal fixations, particularly those related to forms of personal isolation. To some extent, cover-up is intrinsic to oedipal conflict and fantasy, but what is covered up is quite variable. In this paper, the author highlights elements of personal isolation that the patient cultivates in order to protect love
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Book Review: Boundaries, Boundary Crossings, and Boundary Violations J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-09 Kristen Miller Beesley
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WHY I WRITE: TO WRITE IS TO CREATE A UNIVERSE J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-09 Daniel S. Benveniste
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Book Review: Psychoanalytic Reflections on Writing, Cinema and the Arts: Facing Beauty and Loss J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-09 Bradley Collins
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Book Reviews: A Psychoanalytic Understanding of Trauma: Post-Traumatic Mental Functioning, the Zero Process, and the Construction of Reality J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-09 Jerome S. Blackman
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Book Review: Opera on the Couch: Music, Emotional Life, and Unconscious Aspects of Mind J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-09 Timothy Sawyier
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Book Review: Psychoanalysis and Colonialism: A Contemporary Introduction J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-09 Jeffrey A. Bernstein
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Book Review: Parent Work Casebook and Adolescent Casebook J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-09 Laura Whitman
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A BLUE GUITAR, REFLECTIONS ON DISCLOSURE AND RETICENCE (INSPIRED BY JEFFREY BERMAN ON NORMAN HOLLAND, 2021) J. Am. Psychoanal. Assoc. (IF 0.919) Pub Date : 2024-05-09 Ellen Handler Spitz
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Burden of Mental Disorders and Suicide Attributable to Childhood Maltreatment JAMA Psychiatry (IF 25.8) Pub Date : 2024-05-08 Lucinda Grummitt, Jessie R. Baldwin, Johanna Lafoa’i, Katherine M. Keyes, Emma L. Barrett
ImportanceThe proportion of mental disorders and burden causally attributable to childhood maltreatment is unknown.ObjectiveTo determine the contribution of child maltreatment to mental health conditions in Australia, accounting for genetic and environmental confounding.Design, Setting, and ParticipantsThis meta-analysis involved an epidemiological assessment accounting for genetic and environmental
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Role of Inflammation in Short Sleep Duration Across Childhood and Psychosis in Young Adulthood JAMA Psychiatry (IF 25.8) Pub Date : 2024-05-08 Isabel Morales-Muñoz, Steven Marwaha, Rachel Upthegrove, Vanessa Cropley
ImportanceShort sleep duration over a prolonged period in childhood could have a detrimental impact on long-term mental health, including the development of psychosis. Further, potential underlying mechanisms of these associations remain unknown.ObjectiveTo examine the association between persistent shorter nighttime sleep duration throughout childhood with psychotic experiences (PEs) and/or psychotic
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Estimated Number of Children Who Lost a Parent to Drug Overdose in the US From 2011 to 2021 JAMA Psychiatry (IF 25.8) Pub Date : 2024-05-08 Christopher M. Jones, Kun Zhang, Beth Han, Gery P. Guy, Jan Losby, Emily B. Einstein, Miriam Delphin-Rittmon, Nora D. Volkow, Wilson M. Compton
ImportanceParents’ overdose death can have a profound short- and long-term impact on their children, yet little is known about the number of children who have lost a parent to drug overdose in the US.ObjectiveTo estimate the number and rate of children who have lost a parent to drug overdose from 2011 to 2021 overall and by parental age, sex, and race and ethnicity.Design, Setting, and ParticipantsThis
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Associations Between a Primary Care-Delivered Alcohol-Related Brief Intervention and Subsequent Opioid-Related Outcomes Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-06 Dan V. Blalock, Sophia A. Berlin, Theodore Berkowitz, Valerie A. Smith, Charles Wright, Rachel L. Bachrach, Janet M. Grubber
Objective: The co-occurrence of unhealthy alcohol use and opioid misuse is high and associated with increased rates of overdose, emergency health care utilization, and death. The current study examined whether receipt of an alcohol-related brief intervention is associated with reduced risk of negative downstream opioid-related outcomes. Methods: This retrospective cohort study included all VISN-6 Veterans
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Predictors of Substance Use Initiation by Early Adolescence Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-06 ReJoyce Green, Bethany J. Wolf, Andrew Chen, Anna E. Kirkland, Pamela L. Ferguson, Brittney D. Browning, Brittany E. Bryant, Rachel L. Tomko, Kevin M. Gray, Louise Mewton, Lindsay M. Squeglia
Objective: Substance use initiation during early adolescence is associated with later development of substance use and mental health disorders. This study used various domains to predict substance use initiation, defined as trying any nonprescribed substance (e.g., alcohol, tobacco, cannabis), by age 12, using a large longitudinal data set. Methods: Substance-naive youths from the Adolescent Brain
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Neural Correlates of Stress and Alcohol Cue-Induced Alcohol Craving and of Future Heavy Drinking: Evidence of Sex Differences Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-06 Milena Radoman, Nia Fogelman, Cheryl Lacadie, Dongju Seo, Rajita Sinha
Objective: Stress and alcohol cue reactivity are associated with poor treatment outcomes in alcohol use disorder (AUD), but sex-specific neural correlates of stress and alcohol cue–induced craving compared with neutral cue–induced craving and of heavy drinking outcomes in AUD have not been examined. Thus, this study prospectively examined these associations and assessed sex differences. Methods: Treatment-seeking
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Topiramate Versus Naltrexone for Alcohol Use Disorder: A Genotype-Stratified Double-Blind Randomized Controlled Trial Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-06 Kirsten C. Morley, Henry R. Kranzler, Natasha Luquin, Nazila Jamshidi, Claire Adams, Mark Montebello, Chris Tremonti, Gezelle Dali, Warren Logge, Andrew Baillie, Maree Teesson, Ronald Trent, Paul S. Haber
Objective: There have been no well-controlled and well-powered comparative trials of topiramate with other pharmacotherapies for alcohol use disorder (AUD), such as naltrexone. Moreover, the literature is mixed on the effects of two polymorphisms—rs2832407 (in GRIK1) and rs1799971 (in OPRM1)—on response to topiramate and naltrexone, respectively. The authors sought to examine the comparative effectiveness
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Alcohol Use Disorder and Chronic Pain: An Overlooked Epidemic Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-06 Joao P. De Aquino, Matthew E. Sloan, Julio C. Nunes, Gabriel P. A. Costa, Jasmin L. Katz, Debora de Oliveira, Jocelyn Ra, Victor M. Tang, Ismene L. Petrakis
Alcohol use disorder (AUD) and chronic pain disorders are pervasive, multifaceted medical conditions that often co-occur. However, their comorbidity is often overlooked, despite its prevalence and clinical relevance. Individuals with AUD are more likely to experience chronic pain than the general population. Conversely, individuals with chronic pain commonly alleviate their pain with alcohol, which
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Understanding and Addressing Widening Racial Inequalities in Drug Overdose Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-06 Joseph R. Friedman, Max Jordan Nguemeni Tiako, Helena Hansen
The fourth wave of the United States overdose crisis—driven by the polysubstance use of fentanyl with stimulants and other synthetic substances—has driven sharply escalating racial/ethnic inequalities in drug overdose death rates. Here the authors present a detailed portrait of the latest overdose trends and synthesize the literature to describe where, how, and why these inequalities are worsening
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Harm Reduction for Opioid Use Disorder: Strategies and Outcome Metrics Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-06 Jennifer D. Ellis, Kelly E. Dunn, Andrew S. Huhn
Opioid overdose deaths and opioid-related harms have reached unprecedented levels, particularly as compounds such as xylazine and fentanyl have infiltrated the drug supply. Harm reduction strategies are especially relevant in this climate, as they aim to reduce drug-related harms independently of whether an individual chooses to enter treatment or abstain from opioid use. Assessment of harm reduction
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Vaccines as Immunotherapies for Substance Use Disorders Am. J. Psychiatry (IF 17.7) Pub Date : 2024-05-06 Thomas R. Kosten
Substance use disorders (SUD) present a worldwide challenge with few effective therapies except for the relative efficacy of opioid pharmacotherapies, despite limited treatment access. However, the proliferation of illicit fentanyl use initiated a dramatic and cascading epidemic of lethal overdoses. This rise in fentanyl overdoses regenerated an interest in vaccine immunotherapy, which, despite an
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Pharmacogenomic Clinical Support Tools for the Treatment of Depression Am. J. Psychiatry (IF 17.7) Pub Date : 2024-04-30 Matthew L. Baum, Alik S. Widge, Linda L. Carpenter, William M. McDonald, Bruce M. Cohen, Charles B. Nemeroff, On behalf of the American Psychiatric Association (APA) Workgroup on Biomarkers and Novel Treatments
Objective: In this review, the authors update the 2018 position statement of the American Psychiatric Association Council of Research Workgroup on Biomarkers and Novel Treatments on pharmacogenomic (PGx) tools for treatment selection in depression. Methods: The literature was reviewed for new clinical trials and meta-analyses, published from 2017 to 2022, of studies using PGx tools for treatment selection
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Geographic Penetration of Private Equity Ownership in Outpatient and Residential Behavioral Health JAMA Psychiatry (IF 25.8) Pub Date : 2024-05-01 Jane M. Zhu, Emmanuel Greenberg, Marissa King, Susan Busch
This cross-sectional study estimates the geographic penetration of private equity–owned outpatient mental health and substance use disorder practices across the US.
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Prospective and Retrospective Measures of Child Maltreatment and Their Association With Psychopathology JAMA Psychiatry (IF 25.8) Pub Date : 2024-05-01 Jessie R. Baldwin, Oonagh Coleman, Emma R. Francis, Andrea Danese
ImportanceProspective and retrospective measures of childhood maltreatment identify largely different groups of individuals. However, it is unclear if these measures are differentially associated with psychopathology.ObjectiveTo analyze the associations of prospective and retrospective measures of childhood maltreatment with psychopathology.Data SourcesBased on a preregistered protocol, Embase, PsycInfo
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Efficacy and Safety of Xanomeline-Trospium Chloride in Schizophrenia JAMA Psychiatry (IF 25.8) Pub Date : 2024-05-01 Inder Kaul, Sharon Sawchak, David P. Walling, Carol A. Tamminga, Alan Breier, Haiyuan Zhu, Andrew C. Miller, Steven M. Paul, Stephen K. Brannan
ImportanceA significant need exists for new antipsychotic medications with different mechanisms of action, greater efficacy, and better tolerability than existing agents. Xanomeline is a dual M1/M4 preferring muscarinic receptor agonist with no direct D2 dopamine receptor blocking activity. KarXT combines xanomeline with the peripheral muscarinic receptor antagonist trospium chloride with the goal
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Association of Lower Rostral Anterior Cingulate GABA+ and Dysregulated Cortisol Stress Response With Altered Functional Connectivity in Young Adults With Lifetime Depression: A Multimodal Imaging Investigation of Trait and State Effects Am. J. Psychiatry (IF 17.7) Pub Date : 2024-04-30 Maria Ironside, Jessica M. Duda, Amelia D. Moser, Laura M. Holsen, Chun S. Zuo, Fei Du, Sarah Perlo, Christine E. Richards, Xi Chen, Lisa D. Nickerson, Kaylee E. Null, Shiba M. Esfand, Madeline M. Alexander, David J. Crowley, Meghan Lauze, Madhusmita Misra, Jill M. Goldstein, Diego A. Pizzagalli
Objective: Preclinical work suggests that excess glucocorticoids and reduced cortical γ-aminobutyric acid (GABA) may affect sex-dependent differences in brain regions implicated in stress regulation and depressive phenotypes. The authors sought to address a critical gap in knowledge, namely, how stress circuitry is functionally affected by glucocorticoids and GABA in current or remitted major depressive
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Shared and Specific Neural Correlates of Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder: A Meta-Analysis of 243 Task-Based Functional MRI Studies Am. J. Psychiatry (IF 17.7) Pub Date : 2024-04-30 Hiroki Tamon, Junya Fujino, Takashi Itahashi, Lennart Frahm, Valeria Parlatini, Yuta Y. Aoki, Francisco Xavier Castellanos, Simon B. Eickhoff, Samuele Cortese
Objective: To investigate shared and specific neural correlates of cognitive functions in attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), the authors performed a comprehensive meta-analysis and considered a balanced set of neuropsychological tasks across the two disorders. Methods: A broad set of electronic databases was searched up to December 4, 2022, for task-based
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Post-Dobbs Challenges in Research and Patient Protections JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-24 Aimee N. C. Campbell, Shelly F. Greenfield
This Viewpoint describes the challenges for clinical research and participant protections following the US Supreme Court ruling in Dobbs v Jackson Women’s Health Organization.
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Cognitive Behavior Therapy vs Mindfulness in Treatment of Prolonged Grief Disorder JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-24 Richard A. Bryant, Suzanna Azevedo, Srishti Yadav, Catherine Cahill, Lucy Kenny, Fiona Maccallum, Jenny Tran, Jasmine Choi-Christou, Natasha Rawson, Julia Tockar, Benjamin Garber, Dharani Keyan, Katie S. Dawson
ImportanceAlthough grief-focused cognitive behavior therapies are the most empirically supported treatment for prolonged grief disorder, many people find this treatment difficult. A viable alternative for treatment is mindfulness-based cognitive therapy.ObjectiveTo examine the relative efficacies of grief-focused cognitive behavior therapy and mindfulness-based cognitive therapy to reduce prolonged
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Adolescents Who Do Not Endorse Risk via the Patient Health Questionnaire Before Self-Harm or Suicide JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-24 Jean P. Flores, Geoffrey Kahn, Robert B. Penfold, Elizabeth A. Stuart, Brian K. Ahmedani, Arne Beck, Jennifer M. Boggs, Karen J. Coleman, Yihe G. Daida, Frances L. Lynch, Julie E. Richards, Rebecca C. Rossom, Gregory E. Simon, Holly C. Wilcox
ImportanceGiven that the Patient Health Questionnaire (PHQ) item 9 is commonly used to screen for risk of self-harm and suicide, it is important that clinicians recognize circumstances when at-risk adolescents may go undetected.ObjectiveTo understand characteristics of adolescents with a history of depression who do not endorse the PHQ item 9 before a near-term intentional self-harm event or suicide
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Recreational Marijuana Laws and Teen Marijuana Use, 1993-2021 JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-24 D. Mark Anderson, Hao T. Fe, Yang Liang, Joseph J. Sabia
This cross-sectional study uses data from the Youth Risk Behavior surveys to assess the association of state-level recreational marijuana laws and youth marijuana use.
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Prevalence of Mental Health Disorders Among Individuals Experiencing Homelessness JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-17 Rebecca Barry, Jennifer Anderson, Lan Tran, Anees Bahji, Gina Dimitropoulos, S. Monty Ghosh, Julia Kirkham, Geoffrey Messier, Scott B. Patten, Katherine Rittenbach, Dallas Seitz
ImportanceSeveral factors may place people with mental health disorders, including substance use disorders, at increased risk of experiencing homelessness and experiencing homelessness may also increase the risk of developing mental health disorders. Meta-analyses examining the prevalence of mental health disorders among people experiencing homelessness globally are lacking.ObjectiveTo determine the
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Digital Mental Health’s Unstable Dichotomy—Wellness and Health JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-17 John Torous, Joseph Firth, Simon B. Goldberg
This Viewpoint discusses the unacknowledged risks and harms and unrealized clinical benefits of digital mental wellness and health technologies and offers suggestions for ways to catalyze the next phase of these technologies by focusing on safety, evidence, and engagement.
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Examining Sex Differences in Autism Heritability JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-17 Sven Sandin, Benjamin H. K. Yip, Weiyao Yin, Lauren A. Weiss, Joseph D. Dougherty, Stuart Fass, John N. Constantino, Zhu Hailin, Tychele N. Turner, Natasha Marrus, David H. Gutmann, Stephan J. Sanders, Benjamin Christoffersson
ImportanceAutism spectrum disorder (ASD) is a neurodevelopmental disorder more prevalent in males than in females. The cause of ASD is largely genetic, but the association of genetics with the skewed sex ratio is not yet understood. To our knowledge, no large population-based study has provided estimates of heritability by sex.ObjectiveTo estimate the sex-specific heritability of ASD.Design, Setting
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From clinical psychiatry to implementation research and back again Lancet Psychiatry (IF 64.3) Pub Date : 2024-04-15 The Lancet Psychiatry
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Non-fatal suicide behaviours: recommendations for addressing mental health Lancet Psychiatry (IF 64.3) Pub Date : 2024-04-15 Clara González-Sanguino, Berta Ausín Benito, Manuel Muñoz López
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Climate change and mental health: a call for a global research agenda Lancet Psychiatry (IF 64.3) Pub Date : 2024-04-15 Amruta Nori-Sarma, Sandro Galea
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Heat and hospital admission via the emergency department for people with intellectual disability, autism, and mental disorders in South Korea: a nationwide, time-stratified, case-crossover study Lancet Psychiatry (IF 64.3) Pub Date : 2024-04-15 Jinah Park MPH, Ayoung Kim BSc, Prof Michelle L Bell PhD, Prof Ho Kim PhD, Prof Whanhee Lee PhD
Given the anticipated increase in ambient temperature due to climate change, the hazardous effects of heat on health have been extensively studied; however, its impact on people with intellectual disability, autism, and mental illness is largely unknown. We aimed to estimate the association between heat and hospitalisation through the emergency department (ED) among people with these mental disorders
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Non-fatal suicide behaviours across phases in the COVID-19 pandemic: a population-based study in a Catalan cohort Lancet Psychiatry (IF 64.3) Pub Date : 2024-04-15 Víctor Serrano-Gimeno MD, Alba Diestre MD, Marina Agustin-Alcain MD, Maria J Portella PhD, Javier de Diego-Adeliño MD PhD, Thaïs Tiana PsyD, Nora Cheddi MD, Alejandro Distefano MD, Guillermo Dominguez MD, Marina Arias MMath, Victor Cardoner MMath, Dolors Puigdemont MD PhD, Prof Victor Perez MD PhD, Prof Narcís Cardoner MD PhD
The COVID-19 pandemic has been extensively discussed in the context of its effect on mental health. Although global suicide rates have remained stable during the pandemic, the specific effect on non-fatal suicide behaviours during and after the pandemic remains underexplored. This study aims to investigate patterns of non-fatal suicide behaviours before, during, and after the pandemic. In this cohort
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Essentials of Informed Consent to Psychedelic Medicine JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-10 Mason Marks, Rebecca W. Brendel, Carmel Shachar, I. Glenn Cohen
ImportanceInterest in administering psychedelic agents as mental health treatment is growing rapidly. As drugmakers invest in developing psychedelic medicines for several psychiatric indications, lawmakers are enacting legal reforms to speed access globally, and health agencies are preparing to approve these treatments. Meanwhile, US states, such as Oregon and Colorado, are making psychedelics available
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Trajectories of Adolescent Media Use and Their Associations With Psychotic Experiences JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-10 Vincent Paquin, Manuela Ferrari, Soham Rej, Michel Boivin, Isabelle Ouellet-Morin, Marie-Claude Geoffroy, Jai L. Shah
ImportanceAdolescent media use is thought to influence mental health, but whether it is associated with psychotic experiences (PEs) is unclear.ObjectiveTo examine longitudinal trajectories of adolescent media use and their associations with PEs at 23 years of age.Design, Setting, and ParticipantsThis cohort study included participants from the Québec Longitudinal Study of Child Development (1998-2021):
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Medicaid Reentry Section 1115 Demonstration Opportunity JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-03 William C. Lieber, Jade Zhang, Lauren Brinkley-Rubinstein
This Viewpoint explains the Medicaid Reentry Section 1115 Demonstration Opportunity of April 2023 and recommends strategies to optimize this opportunity for community connection and mental health care.
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A Dynamical Systems View of Psychiatric Disorders—Theory JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-03 Marten Scheffer, Claudi L. Bockting, Denny Borsboom, Roshan Cools, Clara Delecroix, Jessica A. Hartmann, Kenneth S. Kendler, Ingrid van de Leemput, Han L. J. van der Maas, Egbert van Nes, Mark Mattson, Pat D. McGorry, Barnaby Nelson
ImportancePsychiatric disorders may come and go with symptoms changing over a lifetime. This suggests the need for a paradigm shift in diagnosis and treatment. Here we present a fresh look inspired by dynamical systems theory. This theory is used widely to explain tipping points, cycles, and chaos in complex systems ranging from the climate to ecosystems.ObservationsIn the dynamical systems view, we
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Susceptibility to Treatment-Resistant Depression Within Families JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-03 Chih-Ming Cheng, Mu-Hong Chen, Shih-Jen Tsai, Wen-Han Chang, Chia-Fen Tsai, Wei-Chen Lin, Ya-Mei Bai, Tung-Ping Su, Tzeng-Ji Chen, Cheng-Ta Li
ImportanceAntidepressant responses and the phenotype of treatment-resistant depression (TRD) are believed to have a genetic basis. Genetic susceptibility between the TRD phenotype and other psychiatric disorders has also been established in previous genetic studies, but population-based cohort studies have not yet provided evidence to support these outcomes.ObjectiveTo estimate the TRD susceptibility
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A Dynamical Systems View of Psychiatric Disorders—Practical Implications JAMA Psychiatry (IF 25.8) Pub Date : 2024-04-03 Marten Scheffer, Claudi L. Bockting, Denny Borsboom, Roshan Cools, Clara Delecroix, Jessica A. Hartmann, Kenneth S. Kendler, Ingrid van de Leemput, Han L. J. van der Maas, Egbert van Nes, Mark Mattson, Pat D. McGorry, Barnaby Nelson
ImportanceDynamical systems theory is widely used to explain tipping points, cycles, and chaos in complex systems ranging from the climate to ecosystems. It has been suggested that the same theory may be used to explain the nature and dynamics of psychiatric disorders, which may come and go with symptoms changing over a lifetime. Here we review evidence for the practical applicability of this theory
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Health economics of psychological interventions in PTSD Lancet Psychiatry (IF 64.3) Pub Date : 2024-03-27 Judith Dams
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Cost-effectiveness of therapist-assisted internet-delivered psychological therapies for PTSD differing in trauma focus in England: an economic evaluation based on the STOP-PTSD trial Lancet Psychiatry (IF 64.3) Pub Date : 2024-03-27 Ed Penington MSc, Prof Jennifer Wild DClinPsy, Emma Warnock-Parkes DClinPsy, Nick Grey DclinPsy, Hannah Murray DClinPsy, Alice Kerr DClinPsy, Richard Stott DclinPsy, Alexander Rozental PhD, Prof Gerhard Andersson PhD, Prof David M Clark DPhil, Apostolos Tsiachristas PhD, Prof Anke Ehlers PhD
Although there are effective psychological treatments for post-traumatic stress disorder (PTSD), they remain inaccessible for many people. Digitally enabled therapy is a way to overcome this problem; however, there is little evidence on which forms of these therapies are most cost effective in PTSD. We aimed to assess the cost-effectiveness of the STOP-PTSD trial, which evaluated two therapist-assisted
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Validation of a Multivariable Model to Predict Suicide Attempt in a Mental Health Intake Sample JAMA Psychiatry (IF 25.8) Pub Date : 2024-03-27 Santiago Papini, Honor Hsin, Patricia Kipnis, Vincent X. Liu, Yun Lu, Kristine Girard, Stacy A. Sterling, Esti M. Iturralde
ImportanceGiven that suicide rates have been increasing over the past decade and the demand for mental health care is at an all-time high, targeted prevention efforts are needed to identify individuals seeking to initiate mental health outpatient services who are at high risk for suicide. Suicide prediction models have been developed using outpatient mental health encounters, but their performance