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Maize tassel number and tasseling stage monitoring based on near-ground and UAV RGB images by improved YoloV8 Precision Agric. (IF 6.2) Pub Date : 2024-04-29 Xun Yu, Dameng Yin, Honggen Xu, Francisco Pinto Espinosa, Urs Schmidhalter, Chenwei Nie, Yi Bai, Sindhuja Sankaran, Bo Ming, Ningbo Cui, Wenbin Wu, Xiuliang Jin
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I strive to make the Great Barrier Reef more resilient to heat stress Nature (IF 64.8) Pub Date : 2024-04-29
Matthew Nitschke grows coral symbionts in a slowly warming tank to prepare reef life for climate change.
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Superconductivity hunt gets boost from China's $220 million physics 'playground' Nature (IF 64.8) Pub Date : 2024-04-29
From extreme cold to strong magnets and high pressures, the Synergetic Extreme Condition User Facility (SECUF) provides conditions for researching these potential wonder materials.
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Elephant-nose fish ‘see’ farther by electric sensing when in groups Nature (IF 64.8) Pub Date : 2024-04-29
The elephant-nose fish detects electric pulses from its neighbours to extend the distance over which it senses objects.
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85 million cells — and counting — at your fingertips Nature (IF 64.8) Pub Date : 2024-04-29
Chan Zuckerberg CELL by GENE Discover aims to be a one-stop shop for single-cell RNA sequencing data storage, access and analysis.
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Daily briefing: Gaze upon the most detailed Moon maps ever made Nature (IF 64.8) Pub Date : 2024-04-26
The new Geologic Atlas took more than 100 researchers over a decade to compile. Plus, how gliding marsupials got their ‘wings’ and H5N1 bird flu virus material has been detected in US milk.
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Expression and Purification of Recombinant Bowman–Birk Trypsin Inhibitor from Foxtail Millet Bran and Its Anticolorectal Cancer Effect In Vitro and In Vivo J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-27 Huimin Zhang, Qinqin Qiao, Yaru Zhao, Lizhen Zhang, Jiangying Shi, Nifei Wang, Zhuoyu Li, Shuhua Shan
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Antifungal Activity of Novel Indole Derivatives Containing 1,3,4-Thiadiazole J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-26 Bangcan He, Yuzhi Hu, Li Xing, Yishan Qing, Kaini Meng, Wei Zeng, Zhiling Sun, Zhenchao Wang, Wei Xue
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Key Odorants Forming Aroma of Polish Mead: Influence of the Raw Material and Manufacturing Processes J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-26 Daria Cicha-Wojciechowicz, Stephanie Frank, Martin Steinhaus, Małgorzata Anna Majcher
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A new method for satellite-based remote sensing analysis of plant-specific biomass yield patterns for precision farming applications Precision Agric. (IF 6.2) Pub Date : 2024-04-28 Ludwig Hagn, Johannes Schuster, Martin Mittermayer, Kurt-Jürgen Hülsbergen
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Comparative study of interpolation methods for low-density sampling Precision Agric. (IF 6.2) Pub Date : 2024-04-28 F. H. S. Karp, V. Adamchuk, P. Dutilleul, A. Melnitchouck
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Bird flu virus has been spreading in US cows for months, RNA reveals Nature (IF 64.8) Pub Date : 2024-04-27
Genomic analysis suggests that the outbreak probably began in December or January, but a shortage of data is hampering efforts to pin down the source.
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Want to make a difference? Try working at an environmental non-profit organization Nature (IF 64.8) Pub Date : 2024-04-26
Moving to non-profit work requires researchers to shift their mindset to focus on applied science for policymaking and conservation practice.
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Corporate emissions targets and the neglect of future innovators Science (IF 56.9) Pub Date : 2024-04-26 Yann Robiou du Pont, Joeri Rogelj, Angel Hsu, Detlef van Vuuren, Andreas G. F. Hoepner
Widely recognized as key partners for achieving international climate goals (1, 2), businesses like to indicate that their targets and activities are “Paris-aligned.” In response, research and initiatives have emerged to guide and assess whether companies’ targets represent an adequate mitigation effort to achieve the Paris Agreement. Here, we highlight conceptual limitations of effort-sharing approaches
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A sound beginning of life starts before birth Science (IF 56.9) Pub Date : 2024-04-26 Hans Slabbekoorn
The acoustic environment of animals and humans has never been quiet, encompassing all sounds, from natural to those made by humans. The effect of sound on physiology and development starts before birth, which is why a world that grows increasingly more noisy, with loud outdoor entertainment, construction, and traffic, is a concern. On page 475 of this issue, Meillère et al. (1) report that exposure
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Microbes and vitamin D aid immunotherapy Science (IF 56.9) Pub Date : 2024-04-26 Fabien Franco, Kathy D. McCoy
Tremendous progress has been made in improving cancer immunotherapy, which is now established as a pillar for cancer treatment. Immune checkpoint inhibitors (ICIs) enhance antitumoral T cell responses by blocking interactions of the inhibitory receptors cytotoxic T lymphocyte–associated protein 4 (CTLA-4) or programmed cell death protein 1 (PD-1) that are expressed on T cells with their ligands. ICIs
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Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules Science (IF 56.9) Pub Date : 2024-04-26 Daniel O. Dodd, Sabrina Mechaussier, Patricia L. Yeyati, Fraser McPhie, Jacob R. Anderson, Chen Jing Khoo, Amelia Shoemark, Deepesh K. Gupta, Thomas Attard, Maimoona A. Zariwala, Marie Legendre, Diana Bracht, Julia Wallmeier, Miao Gui, Mahmoud R. Fassad, David A. Parry, Peter A. Tennant, Alison Meynert, Gabrielle Wheway, Lucas Fares-Taie, Holly A. Black, Rana Mitri-Frangieh, Catherine Faucon, Josseline
Tubulin, one of the most abundant cytoskeletal building blocks, has numerous isotypes in metazoans encoded by different conserved genes. Whether these distinct isotypes form cell type– and context-specific microtubule structures is poorly understood. Based on a cohort of 12 patients with primary ciliary dyskinesia as well as mouse mutants, we identified and characterized variants in the TUBB4B isotype
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Exploring the Relationships Between Bacterial Community, Taste-Enhancing Peptides and Aroma in Thai Fermented Fish (Pla-ra) J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-26 Preecha Phuwapraisirisan, Apiniharn Phewpan, Kannapon Lopetcharat, Corinna Dawid, Thomas Hofmann, Suwimon Keeratipibul
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Design, Synthesis, and Herbicidal Evaluation of Pyrrolidinone-Containing 2-Phenylpyridine Derivatives as Novel Protoporphyrinogen Oxidase Inhibitors J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-26 Meng Zhang, Hui Cai, Chen Pang, Zhongyin Chen, Dan Ling, Zhichao Jin, Yonggui Robin Chi
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Molecular Mechanisms of Fucoxanthin in Alleviating Lipid Deposition in Metabolic Associated Fatty Liver Disease J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-26 Shouxing Yang, Jinhai Li, Liping Yan, Yu Wu, Lin Zhang, Boyang Li, Haibin Tong, Xiaochun Lin
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Systems Metabolic Engineering for Efficient Violaxanthin Production in Yeast J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-26 Jia Wang, Xiao Zhou, Kexin Li, Herong Wang, Chenglong Zhang, Yi Shi, Mingdong Yao, Ying Wang, Wenhai Xiao
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Influence of Sodium Chloride on Human Bitter Taste Receptor Responses J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Praveen Kumar, Maik Behrens
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Conformation-Activity Mechanism of Alcalase Hydrolysis for Reducing In Vitro Allergenicity of Instant Soy Milk Powder J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Jie Ding, Libo Qi, Limin Zhong, Shan Shang, Chunyan Zhu, Songyi Lin
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Computation-Guided Rational Design of Cysteine-Less Protein Variants in Engineered hCGL J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-23 Qian Zhang, Shuai Fan, Mengjia Tang, Chenyu Wang, Xiaoxiao Li, Yuanyuan Jin, Zhaoyong Yang
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Mulberry Leaf-Derived Morin Activates β-Catenin by Binding to Frizzled7 to Promote Intestinal Stem Cell Expansion upon Heat-Stable Enterotoxin b Injury J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-23 Jia-yi Zhou, Wen-wen Xie, Ting-cai Hu, Xiao-fan Wang, Hui-chao Yan, Xiu-qi Wang
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Coculture of Acinetobacter johnsonii and Shewanella putrefaciens Contributes to the ABC Transporter that Impacts Cold Adaption in the Aquatic Food Storage Environment J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-22 Xin-Yun Wang, Jun Yan, Jing Xie
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Audio long read: Why loneliness is bad for your health Nature (IF 64.8) Pub Date : 2024-04-26
Listen to an audio version of a recent Nature Feature.
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Could a rare mutation that causes dwarfism also slow ageing? Nature (IF 64.8) Pub Date : 2024-04-26
People with Laron syndrome have a low risk of heart disease and a number of other age-related disorders, hinting at strategies for new treatments.
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Future of Humanity Institute shuts: what’s next for ‘deep future’ research? Nature (IF 64.8) Pub Date : 2024-04-26
Researchers from several disciplines hope to predict — and prevent — scenarios that pose risks to humanity.
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Garden-variety fungus is an expert at environmental clean-ups Nature (IF 64.8) Pub Date : 2024-04-25
The common fungus Aspergillus niger removes both heavy metals and organic pollutants from its surroundings.
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Air-travel climate-change emissions detailed for nearly 200 nations Nature (IF 64.8) Pub Date : 2024-04-25
Carbon emissions from flights that departed from low- and middle-income countries in 2019 totalled 417 million tonnes.
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Rat neurons repair mouse brains — and restore sense of smell Nature (IF 64.8) Pub Date : 2024-04-25
Scientists develop hybrid mice by filling in missing cells and structures in their brains with rat stem cells.
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Hello puffins, goodbye belugas: changing Arctic fjord hints at our climate future Nature (IF 64.8) Pub Date : 2024-04-25
Stunning images show an ecosystem’s upheaval as it warms at an alarming pace.
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Scientists urged to collect royalties from the ‘magic money tree’ Nature (IF 64.8) Pub Date : 2024-04-25
By joining a collecting society, researchers can ensure they are paid when copyrighted book content and papers are reproduced.
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Daily briefing: How an unlikely friendship with Jung influenced Pauli’s physics Nature (IF 64.8) Pub Date : 2024-04-25
A patient-analyst relationship to psychoanalyst Carl Jung that evolved into a friendship deeply influenced physicist Wolfgang Pauli’s work. Plus, organoids shed light on cancer and other diseases, and medieval graves reveal secrets of a mysterious nomadic people.
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NIH pay raise for postdocs and PhD students could have US ripple effect Nature (IF 64.8) Pub Date : 2024-04-25
Salary increases for the 17,000-plus recipients of an NIH research award could lead to increases in other academic settings.
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Bird flu in US cows: is the milk supply safe? Nature (IF 64.8) Pub Date : 2024-04-25
Pasteurized milk is probably not a threat to people, but fresh milk droplets on milking equipment could be spreading the virus in a herd.
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Judge dismisses superconductivity physicist’s lawsuit against university Nature (IF 64.8) Pub Date : 2024-04-25
Ranga Dias sued his university, in part, for allegedly conducting a biased investigation, which found he had committed extensive scientific misconduct.
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Daily briefing: The origins of bioluminescence in animals date back over half a billion years Nature (IF 64.8) Pub Date : 2024-04-24
Octocorals probably evolved the ability to make light when the first animals developed eyes. Plus, the WHO has redefined ‘airborne transmission’ and how artificial intelligence is changing weapons of war.
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How DNA encodes the start of transcription Science (IF 56.9) Pub Date : 2024-04-26 Jun Wang, Vikram Agarwal
The central dogma of molecular biology outlines the flow of genetic information from DNA to RNA to proteins. With a limited vocabulary of four nucleotides (A, C, G, and T), DNA encodes an extensive instruction set, including the chromosomal positions where RNAs begin to be transcribed and the magnitudes of their expression. This process, known as transcription initiation (1), begins at transcription
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Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-04-26 Fredrick Kizito, Kien Nguyen, Uri Mbonye, Meenakshi Shukla, Benjamin Luttge, Mary Ann Checkley, Anna Agaponova, Konstantin Leskov, Jonathan Karn
Using an immunofluorescence assay based on CRISPR-dCas9-gRNA complexes that selectively bind to the HIV LTR (HIV Cas-FISH), we traced changes in HIV DNA localization in primary effector T cells from early infection until the cells become quiescent as they transition to memory cells. Unintegrated HIV DNA colocalized with CPSF6 and HIV capsid (CA, p24) was found in the cytoplasm and nuclear periphery
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Machine learning enables identification of an alternative yeast galactose utilization pathway Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-04-26 Marie-Claire Harrison, Emily J. Ubbelohde, Abigail L. LaBella, Dana A. Opulente, John F. Wolters, Xiaofan Zhou, Xing-Xing Shen, Marizeth Groenewald, Chris Todd Hittinger, Antonis Rokas
How genomic differences contribute to phenotypic differences is a major question in biology. The recently characterized genomes, isolation environments, and qualitative patterns of growth on 122 sources and conditions of 1,154 strains from 1,049 fungal species (nearly all known) in the yeast subphylum Saccharomycotina provide a powerful, yet complex, dataset for addressing this question. We used a
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Limits of economy and fidelity for programmable assembly of size-controlled triply periodic polyhedra Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-04-26 Carlos M. Duque, Douglas M. Hall, Botond Tyukodi, Michael F. Hagan, Christian D. Santangelo, Gregory M. Grason
We propose and investigate an extension of the Caspar–Klug symmetry principles for viral capsid assembly to the programmable assembly of size-controlled triply periodic polyhedra, discrete variants of the Primitive, Diamond, and Gyroid cubic minimal surfaces. Inspired by a recent class of programmable DNA origami colloids, we demonstrate that the economy of design in these crystalline assemblies—in
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Negative correlation between soil salinity and soil organic carbon variability Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-04-26 Amirhossein Hassani, Pete Smith, Nima Shokri
Soil organic carbon (SOC) is vital for terrestrial ecosystems, affecting biogeochemical processes, and soil health. It is known that soil salinity impacts SOC content, yet the specific direction and magnitude of SOC variability in relation to soil salinity remain poorly understood. Analyzing 43,459 mineral soil samples (SOC < 150 g kg −1 ) collected across different land covers since 1992, we approximate
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Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-04-26 Qing He, Feng Wang, Michael E. O’Donnell, Huilin Li
The DNA sliding clamp PCNA is a multipurpose platform for DNA polymerases and many other proteins involved in DNA metabolism. The topologically closed PCNA ring needs to be cracked open and loaded onto DNA by a clamp loader, e.g., the well-studied pentameric ATPase complex RFC (RFC1-5). The CTF18-RFC complex is an alternative clamp loader found recently to bind the leading strand DNA polymerase ε and
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Dissection and integration of bursty transcriptional dynamics for complex systems Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-04-26 Cheng Frank Gao, Suriyanarayanan Vaikuntanathan, Samantha J. Riesenfeld
RNA velocity estimation is a potentially powerful tool to reveal the directionality of transcriptional changes in single-cell RNA-sequencing data, but it lacks accuracy, absent advanced metabolic labeling techniques. We developed an approach, TopicVelo , that disentangles simultaneous, yet distinct, dynamics by using a probabilistic topic model, a highly interpretable form of latent space factorization
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Direct nitrous oxide emissions from a crop rotation of maize and mung bean after different long-term fertilizer applications in Thailand Field Crops Res. (IF 5.8) Pub Date : 2024-04-26 Patikorn Sriphirom, Amnat Chidthaisong, Kazuyuki Yagi, Wanida Nobuntou, Suphakarn Luanmanee, Nimaradee Boonapatcharoen, Wantanasak Suksong
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Chemoenzymatic Asymmetric Synthesis of Chiral Triazole Fungicide (R)-Tebuconazole in High Optical Purity Mediated by an Epoxide Hydrolase from Rhodotorula paludigensis J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Die Hu, Xue-Wei Jia, Jia-Lan Lu, Zhi-Yi Lu, Cun-Duo Tang, Feng Xue, Chao Huang, Qing-Gong Ren, Yu-Cai He
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Design, Synthesis, Antibacterial Activity, and Mechanisms of Novel Benzofuran Derivatives Containing Disulfide Moieties J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Jianzhuan Li, Qiu Liu, Sha Li, Lu Zeng, Jiahui Yao, Hongde Li, Zhongjie Shen, Funeng Lu, Zengxue Wu, Baoan Song, Runjiang Song
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LncRNA BlncAD1 Modulates Bovine Adipogenesis by Binding to MYH10, PI3K/Akt Signaling Pathway, and miR-27a-5p/CDK6 Axis J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Xin Li, Zhongyi Hou, Shengbo Meng, Qihui Jia, Shanshan Xing, Zhitong Wang, Mengjuan Chen, Huifen Xu, Ming Li, Hanfang Cai
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Endophytic Bacillus pumilus G5 Interacting with Silicon to Improve Drought Stress Resilience in Glycyrrhiza uralensis Fisch. by Modulating Nitrogen Absorption, Assimilation, and Metabolism Pathways J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Zhanchao Xu, Qiuxian Bai, Xueying Peng, Duoyong Lang, Xinhui Zhang
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20(S)-Protopanaxadiol Exerts Antidepressive Effects in Chronic Corticosterone-Induced Rodent Animal Models as an Activator of Brain-Type Creatine Kinase J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Zhu Zhu, Yao Cheng, Xu Han, Tiantian Wang, Hantao Zhang, Qi Yao, Feiyan Chen, Ling Gu, Dongqing Yang, Lin Chen, Yunan Zhao
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Anti-Coronavirus Potential of Polyether Ionophores: The New Application of Veterinary Antibiotics in Livestock J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Youle Zheng, Jin Feng, Yixin Yu, Min Ling, Yanbin Song, Haijiao Xie, Mengjia Zhang, Wentao Li, Xu Wang
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Molecularly Imprinted Electrochemical Sensor Based on α-Cyclodextrin Inclusion Complex and MXene Modification for Highly Sensitive and Selective Detection of Alkylresorcinols in Whole Wheat Foods J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Yangyang Wen, Mengyao Wang, Weiwei Gong, Hailin Wang, Haoran Fan, Hongyan Li, Jing Wang, Baoguo Sun
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Functional Differentiation of the Succinate Dehydrogenase Subunit SdhC Governs the Sensitivity to SDHI Fungicides, ROS Homeostasis, and Pathogenicity in Fusarium asiaticum J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-25 Wenchan Chen, Xiujuan Li, Lingling Wei, Bin Chen, Chenyang Han, Yabing Duan, Changjun Chen
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Regulation of 2-Acetyl-1-pyrroline Content in Fragrant Rice under Different Temperatures at the Grain-Filling Stage J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-24 Haowen Luo, Qianqian Zhang, Rifang Lai, Simin Zhang, Wentao Yi, Xiangru Tang
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A Potential Multitarget Insect Growth Regulator Candidate: Design, Synthesis, and Biological Activity of Novel Acetamido Derivatives Containing Hexacyclic Pyrazole Carboxamides J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-24 Bingbo Guo, Lei Chen, Shihui Luo, Chunying Wang, Yanjiao Feng, Xiaoyang Li, Congwang Cao, Li Zhang, Qing Yang, Xiaoming Zhang, Xinling Yang
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Antipathogenic Activities of Volatile Organic Compounds Produced by Bacillus velezensis LT1 against Sclerotium rolfsii LC1, the Pathogen of Southern Blight in Coptis chinensis J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-24 Tao Tang, Fanfan Wang, Houyun Huang, Nengneng Xie, Jie Guo, Xiaoliang Guo, Yuanyuan Duan, Xiaoyue Wang, Qingfan Wang, Jingmao You
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Deoxynivalenol Inhibits Progenitor Leydig Cell Development by Stimulating Mitochondrial Fission in Rats J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-24 Jin Yang, Lei Ye, Rong Cui, Ke Zheng, Xinyi Qiao, Mengyun Wang, Ming Su, Xiaoheng Li, Ren-Shan Ge, Yiyan Wang
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Stepwise Flux Optimization for Enhanced GABA Production from Acetate in Escherichia coli J. Agric. Food Chem. (IF 6.1) Pub Date : 2024-04-24 Sun Woo Beck, Dae-yeol Ye, Hyun Gyu Hwang, Gyoo Yeol Jung