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2023 summer warmth unparalleled over the past 2,000 years Nature (IF 64.8) Pub Date : 2024-05-14 Jan Esper, Max Torbenson, Ulf Büntgen
Including an exceptionally warm Northern Hemisphere (NH) summer1,2, 2023 has been reported as the hottest year on record3-5. Contextualizing recent anthropogenic warming against past natural variability is nontrivial, however, because the sparse 19th century meteorological records tend to be too warm6. Here, we combine observed and reconstructed June-August (JJA) surface air temperatures to show that
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Plasmid targeting and destruction by the DdmDE bacterial defence system Nature (IF 64.8) Pub Date : 2024-05-13 Jack P. K. Bravo, Delisa A. Ramos, Rodrigo Fregoso Ocampo, Caiden Ingram, David W. Taylor
While eukaryotic Argonautes play a pivotal role in post-transcriptional gene regulation through nucleic acid cleavage, some short prokaryotic Argonaute variants (pAgos) rely on auxiliary nuclease factors for efficient foreign DNA degradation (1). Here, we elucidate the activation pathway of the DNA Defense Module DdmDE system, which rapidly eliminates small, multicopy plasmids from Vibrio cholerae
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Directly imaging spin polarons in a kinetically frustrated Hubbard system Nature (IF 64.8) Pub Date : 2024-05-08 Max L. Prichard, Benjamin M. Spar, Ivan Morera, Eugene Demler, Zoe Z. Yan, Waseem S. Bakr
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Rhizobia–diatom symbiosis fixes missing nitrogen in the ocean Nature (IF 64.8) Pub Date : 2024-05-09 Bernhard Tschitschko, Mertcan Esti, Miriam Philippi, Abiel T. Kidane, Sten Littmann, Katharina Kitzinger, Daan R. Speth, Shengjie Li, Alexandra Kraberg, Daniela Tienken, Hannah K. Marchant, Boran Kartal, Jana Milucka, Wiebke Mohr, Marcel M. M. Kuypers
Nitrogen (N2) fixation in oligotrophic surface waters is the main source of new nitrogen (N) to the ocean1 and plays a key role in fueling the biological carbon pump2. Oceanic N2 fixation is almost exclusively attributed to cyanobacteria, even though genes encoding nitrogenase, the enzyme fixing N2 into ammonia, are widespread among marine bacteria and archaea3-5. Little is known about these non-cyanobacterial
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Structural mechanism of angiogenin activation by the ribosome Nature (IF 64.8) Pub Date : 2024-05-08 Anna B. Loveland, Cha San Koh, Robin Ganesan, Allan Jacobson, Andrei A. Korostelev
Angiogenin, an RNase A-family protein, promotes angiogenesis and has been implicated in cancer, neurodegenerative diseases, and epigenetic inheritance 1-10. Upon activation during cellular stress, angiogenin cleaves tRNAs at the anticodon loop, resulting in translation repression 11-15. The catalytic activity of isolated angiogenin, however, is very low, and the mechanisms of the enzyme activation
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A secondary atmosphere on the rocky Exoplanet 55 Cancri e Nature (IF 64.8) Pub Date : 2024-05-08 Renyu Hu, Aaron Bello-Arufe, Michael Zhang, Kimberly Paragas, Mantas Zilinskas, Christiaan van Buchem, Michael Bess, Jayshil Patel, Yuichi Ito, Mario Damiano, Markus Scheucher, Apurva V. Oza, Heather A. Knutson, Yamila Miguel, Diana Dragomir, Alexis Brandeker, Brice-Olivier Demory
Characterizing rocky exoplanets is a central endeavor of astronomy, and yet the search for atmospheres on rocky exoplanets has hitherto resulted in either tight upper limits on the atmospheric mass1–3 or inconclusive results4–6. The 1.95-REarth and 8.8-MEarth planet 55 Cnc e, with a predominantly rocky composition and an equilibrium temperature of ~2000 K, may have a volatile envelope (containing molecules
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Accurate structure prediction of biomolecular interactions with AlphaFold 3 Nature (IF 64.8) Pub Date : 2024-05-08 Josh Abramson, Jonas Adler, Jack Dunger, Richard Evans, Tim Green, Alexander Pritzel, Olaf Ronneberger, Lindsay Willmore, Andrew J. Ballard, Joshua Bambrick, Sebastian W. Bodenstein, David A. Evans, Chia-Chun Hung, Michael O’Neill, David Reiman, Kathryn Tunyasuvunakool, Zachary Wu, Akvilė Žemgulytė, Eirini Arvaniti, Charles Beattie, Ottavia Bertolli, Alex Bridgland, Alexey Cherepanov, Miles Congreve
The introduction of AlphaFold 21 has spurred a revolution in modelling the structure of proteins and their interactions, enabling a huge range of applications in protein modelling and design2–6. In this paper, we describe our AlphaFold 3 model with a substantially updated diffusion-based architecture, which is capable of joint structure prediction of complexes including proteins, nucleic acids, small
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Elastic films of single-crystal two-dimensional covalent organic frameworks Nature (IF 64.8) Pub Date : 2024-05-08 Yonghang Yang, Baokun Liang, Jakob Kreie, Mike Hambsch, Zihao Liang, Cheng Wang, Senhe Huang, Xin Dong, Li Gong, Chaolun Liang, Dongyang Lou, Zhipeng Zhou, Jiaxing Lu, Yang Yang, Xiaodong Zhuang, Haoyuan Qi, Ute Kaiser, Stefan C. B. Mannsfeld, Wei Liu, Armin Gölzhäuser, Zhikun Zheng
The properties of polycrystalline materials are often dominated by defects, and two-dimensional (2D) crystals can even be divided and disrupted by a line defect1-3. In contrast, 2D crystals are often required to be processed into films, which are inevitably polycrystalline and contain numerous grain boundaries, and therefore are brittle and fragile, hindering application in flexible electronics, optoelectronics
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Mapping genotypes to chromatin accessibility profiles in single cells Nature (IF 64.8) Pub Date : 2024-05-08 Franco Izzo, Robert M. Myers, Saravanan Ganesan, Levan Mekerishvili, Sanjay Kottapalli, Tamara Prieto, Elliot O. Eton, Theo Botella, Andrew J. Dunbar, Robert L. Bowman, Jesus Sotelo, Catherine Potenski, Eleni P. Mimitou, Maximilian Stahl, Sebastian El Ghaity-Beckley, JoAnn Arandela, Ramya Raviram, Daniel C. Choi, Ronald Hoffman, Ronan Chaligné, Omar Abdel-Wahab, Peter Smibert, Irene M. Ghobrial, Joseph
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Observation of Nagaoka polarons in a Fermi–Hubbard quantum simulator Nature (IF 64.8) Pub Date : 2024-05-08 Martin Lebrat, Muqing Xu, Lev Haldar Kendrick, Anant Kale, Youqi Gang, Pranav Seetharaman, Ivan Morera, Ehsan Khatami, Eugene Demler, Markus Greiner
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Full-colour 3D holographic augmented-reality displays with metasurface waveguides Nature (IF 64.8) Pub Date : 2024-05-08 Manu Gopakumar, Gun-Yeal Lee, Suyeon Choi, Brian Chao, Yifan Peng, Jonghyun Kim, Gordon Wetzstein
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The refinery of the future Nature (IF 64.8) Pub Date : 2024-05-08 Eelco T. C. Vogt, Bert M. Weckhuysen
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All-optical subcycle microscopy on atomic length scales Nature (IF 64.8) Pub Date : 2024-05-08 T. Siday, J. Hayes, F. Schiegl, F. Sandner, P. Menden, V. Bergbauer, M. Zizlsperger, S. Nerreter, S. Lingl, J. Repp, J. Wilhelm, M. A. Huber, Y. A. Gerasimenko, R. Huber
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The intrinsic substrate specificity of the human tyrosine kinome Nature (IF 64.8) Pub Date : 2024-05-08 Tomer M. Yaron-Barir, Brian A. Joughin, Emily M. Huntsman, Alexander Kerelsky, Daniel M. Cizin, Benjamin M. Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M. Orozco, Christina Schoenherr, Cari Sagum, Mark T. Bedford, R. Max Wynn, Shih-Chia Tso, David T. Chuang, Lei Li, Shawn S.-C. Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean
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Chemical short-range disorder in lithium oxide cathodes Nature (IF 64.8) Pub Date : 2024-05-08 Qidi Wang, Zhenpeng Yao, Jianlin Wang, Hao Guo, Chao Li, Dong Zhou, Xuedong Bai, Hong Li, Baohua Li, Marnix Wagemaker, Chenglong Zhao
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Boron catalysis in a designer enzyme Nature (IF 64.8) Pub Date : 2024-05-08 Lars Longwitz, Reuben B. Leveson-Gower, Henriëtte J. Rozeboom, Andy-Mark W. H. Thunnissen, Gerard Roelfes
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Genome organization around nuclear speckles drives mRNA splicing efficiency Nature (IF 64.8) Pub Date : 2024-05-08 Prashant Bhat, Amy Chow, Benjamin Emert, Olivia Ettlin, Sofia A. Quinodoz, Mackenzie Strehle, Yodai Takei, Alex Burr, Isabel N. Goronzy, Allen W. Chen, Wesley Huang, Jose Lorenzo M. Ferrer, Elizabeth Soehalim, Say-Tar Goh, Tara Chari, Delaney K. Sullivan, Mario R. Blanco, Mitchell Guttman
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Ligand cross-feeding resolves bacterial vitamin B12 auxotrophies Nature (IF 64.8) Pub Date : 2024-05-08 Gerrit Wienhausen, Cristina Moraru, Stefan Bruns, Den Quoc Tran, Sabiha Sultana, Heinz Wilkes, Leon Dlugosch, Farooq Azam, Meinhard Simon
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Structural pharmacology and therapeutic potential of 5-methoxytryptamines Nature (IF 64.8) Pub Date : 2024-05-08 Audrey L. Warren, David Lankri, Michael J. Cunningham, Inis C. Serrano, Lyonna F. Parise, Andrew C. Kruegel, Priscilla Duggan, Gregory Zilberg, Michael J. Capper, Vaclav Havel, Scott J. Russo, Dalibor Sames, Daniel Wacker
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An atomic boson sampler Nature (IF 64.8) Pub Date : 2024-05-08 Aaron W. Young, Shawn Geller, William J. Eckner, Nathan Schine, Scott Glancy, Emanuel Knill, Adam M. Kaufman
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Self-oscillating polymeric refrigerator with high energy efficiency Nature (IF 64.8) Pub Date : 2024-05-08 Donglin Han, Yingjing Zhang, Cenling Huang, Shanyu Zheng, Dongyuan Wu, Qiang Li, Feihong Du, Hongxiao Duan, Weilin Chen, Junye Shi, Jiangping Chen, Gang Liu, Xin Chen, Xiaoshi Qian
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Targetable leukaemia dependency on noncanonical PI3Kγ signalling Nature (IF 64.8) Pub Date : 2024-05-08 Qingyu Luo, Evangeline G. Raulston, Miguel A. Prado, Xiaowei Wu, Kira Gritsman, Karley S. Whalen, Kezhi Yan, Christopher A. G. Booth, Ran Xu, Peter van Galen, John G. Doench, Shai Shimony, Henry W. Long, Donna S. Neuberg, Joao A. Paulo, Andrew A. Lane
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Long-range order enabled stability in quantum dot light-emitting diodes Nature (IF 64.8) Pub Date : 2024-05-08 Ya-Kun Wang, Haoyue Wan, Sam Teale, Luke Grater, Feng Zhao, Zhongda Zhang, Hong-Wei Duan, Muhammad Imran, Sui-Dong Wang, Sjoerd Hoogland, Liang-Sheng Liao
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Subaerial weathering drove stabilization of continents Nature (IF 64.8) Pub Date : 2024-05-08 Jesse R. Reimink, Andrew J. Smye
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Discovery of potent small-molecule inhibitors of lipoprotein(a) formation Nature (IF 64.8) Pub Date : 2024-05-08 Nuria Diaz, Carlos Perez, Ana Maria Escribano, Gema Sanz, Julian Priego, Celia Lafuente, Mario Barberis, Luis Calle, Juan Felix Espinosa, Birgit T. Priest, Hong Y. Zhang, Amanda K. Nosie, Joseph V. Haas, Ellen Cannady, Anthony Borel, Albert E. Schultze, J. Michael Sauder, Jörg Hendle, Ken Weichert, Stephen J. Nicholls, Laura F. Michael
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Label-free detection and profiling of individual solution-phase molecules Nature (IF 64.8) Pub Date : 2024-05-08 Lisa-Maria Needham, Carlos Saavedra, Julia K. Rasch, Daniel Sole-Barber, Beau S. Schweitzer, Alex J. Fairhall, Cecilia H. Vollbrecht, Sushu Wan, Yulia Podorova, Anders J. Bergsten, Brandon Mehlenbacher, Zhao Zhang, Lukas Tenbrake, Jovanna Saimi, Lucy C. Kneely, Jackson S. Kirkwood, Hannes Pfeifer, Edwin R. Chapman, Randall H. Goldsmith
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Computationally restoring the potency of a clinical antibody against Omicron Nature (IF 64.8) Pub Date : 2024-05-08 Thomas A. Desautels, Kathryn T. Arrildt, Adam T. Zemla, Edmond Y. Lau, Fangqiang Zhu, Dante Ricci, Stephanie Cronin, Seth J. Zost, Elad Binshtein, Suzanne M. Scheaffer, Bernadeta Dadonaite, Brenden K. Petersen, Taylor B. Engdahl, Elaine Chen, Laura S. Handal, Lynn Hall, John W. Goforth, Denis Vashchenko, Sam Nguyen, Dina R. Weilhammer, Jacky Kai-Yin Lo, Bonnee Rubinfeld, Edwin A. Saada, Tracy Weisenberger
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Decoupling excitons from high-frequency vibrations in organic molecules Nature (IF 64.8) Pub Date : 2024-05-08 Pratyush Ghosh, Antonios M. Alvertis, Rituparno Chowdhury, Petri Murto, Alexander J. Gillett, Shengzhi Dong, Alexander J. Sneyd, Hwan-Hee Cho, Emrys W. Evans, Bartomeu Monserrat, Feng Li, Christoph Schnedermann, Hugo Bronstein, Richard H. Friend, Akshay Rao
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Measurement of the superfluid fraction of a supersolid by Josephson effect Nature (IF 64.8) Pub Date : 2024-05-08 G. Biagioni, N. Antolini, B. Donelli, L. Pezzè, A. Smerzi, M. Fattori, A. Fioretti, C. Gabbanini, M. Inguscio, L. Tanzi, G. Modugno
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Lithium tantalate photonic integrated circuits for volume manufacturing Nature (IF 64.8) Pub Date : 2024-05-08 Chengli Wang, Zihan Li, Johann Riemensberger, Grigory Lihachev, Mikhail Churaev, Wil Kao, Xinru Ji, Junyin Zhang, Terence Blesin, Alisa Davydova, Yang Chen, Kai Huang, Xi Wang, Xin Ou, Tobias J. Kippenberg
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Retuning of hippocampal representations during sleep Nature (IF 64.8) Pub Date : 2024-05-08 Kourosh Maboudi, Bapun Giri, Hiroyuki Miyawaki, Caleb Kemere, Kamran Diba
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A meta-analysis on global change drivers and the risk of infectious disease Nature (IF 64.8) Pub Date : 2024-05-08 Michael B. Mahon, Alexandra Sack, O. Alejandro Aleuy, Carly Barbera, Ethan Brown, Heather Buelow, David J. Civitello, Jeremy M. Cohen, Luz A. de Wit, Meghan Forstchen, Fletcher W. Halliday, Patrick Heffernan, Sarah A. Knutie, Alexis Korotasz, Joanna G. Larson, Samantha L. Rumschlag, Emily Selland, Alexander Shepack, Nitin Vincent, Jason R. Rohr
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Fusion of deterministically generated photonic graph states Nature (IF 64.8) Pub Date : 2024-05-08 Philip Thomas, Leonardo Ruscio, Olivier Morin, Gerhard Rempe
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Complete biosynthesis of QS-21 in engineered yeast Nature (IF 64.8) Pub Date : 2024-05-08 Yuzhong Liu, Xixi Zhao, Fei Gan, Xiaoyue Chen, Kai Deng, Samantha A. Crowe, Graham A. Hudson, Michael S. Belcher, Matthias Schmidt, Maria C. T. Astolfi, Suzanne M. Kosina, Bo Pang, Minglong Shao, Jing Yin, Sasilada Sirirungruang, Anthony T. Iavarone, James Reed, Laetitia B. B. Martin, Amr El-Demerdash, Shingo Kikuchi, Rajesh Chandra Misra, Xiaomeng Liang, Michael J. Cronce, Xiulai Chen, Chunjun Zhan
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Quantum control of a cat qubit with bit-flip times exceeding ten seconds Nature (IF 64.8) Pub Date : 2024-05-06 U. Réglade, A. Bocquet, R. Gautier, J. Cohen, A. Marquet, E. Albertinale, N. Pankratova, M. Hallén, F. Rautschke, L.-A. Sellem, P. Rouchon, A. Sarlette, M. Mirrahimi, P. Campagne-Ibarcq, R. Lescanne, S. Jezouin, Z. Leghtas
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Venus water loss is dominated by HCO+ dissociative recombination Nature (IF 64.8) Pub Date : 2024-05-06 M. S. Chaffin, E. M. Cangi, B. S. Gregory, R. V. Yelle, J. Deighan, R. D. Elliott, H. Gröller
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3D genomic mapping reveals multifocality of human pancreatic precancers Nature (IF 64.8) Pub Date : 2024-05-01 Alicia M. Braxton, Ashley L. Kiemen, Mia P. Grahn, André Forjaz, Jeeun Parksong, Jaanvi Mahesh Babu, Jiaying Lai, Lily Zheng, Noushin Niknafs, Liping Jiang, Haixia Cheng, Qianqian Song, Rebecca Reichel, Sarah Graham, Alexander I. Damanakis, Catherine G. Fischer, Stephanie Mou, Cameron Metz, Julie Granger, Xiao-Ding Liu, Niklas Bachmann, Yutong Zhu, YunZhou Liu, Cristina Almagro-Pérez, Ann Chenyu Jiang
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Chromatin accessibility during human first-trimester neurodevelopment Nature (IF 64.8) Pub Date : 2024-05-01 Camiel C. A. Mannens, Lijuan Hu, Peter Lönnerberg, Marijn Schipper, Caleb C. Reagor, Xiaofei Li, Xiaoling He, Roger A. Barker, Erik Sundström, Danielle Posthuma, Sten Linnarsson
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A deconstruction-reconstruction strategy for pyrimidine diversification Nature (IF 64.8) Pub Date : 2024-05-02 Benjamin J. H. Uhlenbruck, Celena M. Josephitis, Louis de Lescure, Robert S. Paton, Andrew McNally
Structure-Activity Relationship (SAR) studies are fundamental to drug and agrochemical development, yet only a few synthetic strategies apply to the nitrogen heteroaromatics frequently encountered in small molecule candidates.1-3 Here, we present an alternative approach where we convert pyrimidine-containing compounds various other nitrogen heteroaromatics. Transforming pyrmidines into their corre
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A body–brain circuit that regulates body inflammatory responses Nature (IF 64.8) Pub Date : 2024-05-01 Hao Jin, Mengtong Li, Eric Jeong, Felipe Castro-Martinez, Charles S. Zuker
The body-brain axis is emerging as a principal conductor of organismal physiology. It senses and controls organ function1,2, metabolism3 and nutritional state4-6. Here, we show that a peripheral immune insult powerfully activates the body-brain axis to regulate immune responses. We demonstrate that pro- and anti-inflammatory cytokines communicate with distinct populations of vagal neurons to inform
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Paternal microbiome perturbations impact offspring fitness Nature (IF 64.8) Pub Date : 2024-05-01 Ayele Argaw-Denboba, Thomas S. B. Schmidt, Monica Di Giacomo, Bobby Ranjan, Saravanan Devendran, Eleonora Mastrorilli, Catrin T. Lloyd, Danilo Pugliese, Violetta Paribeni, Juliette Dabin, Alessandra Pisaniello, Sergio Espinola, Alvaro Crevenna, Subhanita Ghosh, Neil Humphreys, Olga Boruc, Peter Sarkies, Michael Zimmermann, Peer Bork, Jamie A. Hackett
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Sleep pressure modulates single-neuron synapse number in zebrafish Nature (IF 64.8) Pub Date : 2024-05-01 Anya Suppermpool, Declan G. Lyons, Elizabeth Broom, Jason Rihel
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Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1 Nature (IF 64.8) Pub Date : 2024-05-01 Yeeun Son, Timothy C. Kenny, Artem Khan, Kıvanç Birsoy, Richard K. Hite
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Probing single electrons across 300-mm spin qubit wafers Nature (IF 64.8) Pub Date : 2024-05-01 Samuel Neyens, Otto K. Zietz, Thomas F. Watson, Florian Luthi, Aditi Nethwewala, Hubert C. George, Eric Henry, Mohammad Islam, Andrew J. Wagner, Felix Borjans, Elliot J. Connors, J. Corrigan, Matthew J. Curry, Daniel Keith, Roza Kotlyar, Lester F. Lampert, Mateusz T. Mądzik, Kent Millard, Fahd A. Mohiyaddin, Stefano Pellerano, Ravi Pillarisetty, Mick Ramsey, Rostyslav Savytskyy, Simon Schaal, Guoji
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Airway hillocks are injury-resistant reservoirs of unique plastic stem cells Nature (IF 64.8) Pub Date : 2024-05-01 Brian Lin, Viral S. Shah, Chaim Chernoff, Jiawei Sun, Gergana G. Shipkovenska, Vladimir Vinarsky, Avinash Waghray, Jiajie Xu, Andrew D. Leduc, Constantin A. Hintschich, Manalee Vishnu Surve, Yanxin Xu, Diane E. Capen, Jorge Villoria, Zhixun Dou, Lida P. Hariri, Jayaraj Rajagopal
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Geographic variation of mutagenic exposures in kidney cancer genomes Nature (IF 64.8) Pub Date : 2024-05-01 Sergey Senkin, Sarah Moody, Marcos Díaz-Gay, Behnoush Abedi-Ardekani, Thomas Cattiaux, Aida Ferreiro-Iglesias, Jingwei Wang, Stephen Fitzgerald, Mariya Kazachkova, Raviteja Vangara, Anh Phuong Le, Erik N. Bergstrom, Azhar Khandekar, Burçak Otlu, Saamin Cheema, Calli Latimer, Emily Thomas, Joshua Ronald Atkins, Karl Smith-Byrne, Ricardo Cortez Cardoso Penha, Christine Carreira, Priscilia Chopard, Valérie
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Mechanics of human embryo compaction Nature (IF 64.8) Pub Date : 2024-05-01 Julie Firmin, Nicolas Ecker, Diane Rivet Danon, Özge Özgüç, Virginie Barraud Lange, Hervé Turlier, Catherine Patrat, Jean-Léon Maître
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Temporal dynamics of the multi-omic response to endurance exercise training Nature (IF 64.8) Pub Date : 2024-05-01
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Bevel-edge epitaxy of ferroelectric rhombohedral boron nitride single crystal Nature (IF 64.8) Pub Date : 2024-05-01 Li Wang, Jiajie Qi, Wenya Wei, Mengqi Wu, Zhibin Zhang, Xiaomin Li, Huacong Sun, Quanlin Guo, Meng Cao, Qinghe Wang, Chao Zhao, Yuxuan Sheng, Zhetong Liu, Can Liu, Muhong Wu, Zhi Xu, Wenlong Wang, Hao Hong, Peng Gao, Menghao Wu, Zhu-Jun Wang, Xiaozhi Xu, Enge Wang, Feng Ding, Xiaorui Zheng, Kaihui Liu, Xuedong Bai
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Mitochondrial transfer mediates endothelial cell engraftment through mitophagy Nature (IF 64.8) Pub Date : 2024-05-01 Ruei-Zeng Lin, Gwang-Bum Im, Allen Chilun Luo, Yonglin Zhu, Xuechong Hong, Joseph Neumeyer, Hong-Wen Tang, Norbert Perrimon, Juan M. Melero-Martin
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Frequent disturbances enhanced the resilience of past human populations Nature (IF 64.8) Pub Date : 2024-05-01 Philip Riris, Fabio Silva, Enrico Crema, Alessio Palmisano, Erick Robinson, Peter E. Siegel, Jennifer C. French, Erlend Kirkeng Jørgensen, Shira Yoshi Maezumi, Steinar Solheim, Jennifer Bates, Benjamin Davies, Yongje Oh, Xiaolin Ren
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Structural and molecular basis of choline uptake into the brain by FLVCR2 Nature (IF 64.8) Pub Date : 2024-05-01 Rosemary J. Cater, Dibyanti Mukherjee, Eva Gil-Iturbe, Satchal K. Erramilli, Ting Chen, Katie Koo, Nicolás Santander, Andrew Reckers, Brian Kloss, Tomasz Gawda, Brendon C. Choy, Zhening Zhang, Aditya Katewa, Amara Larpthaveesarp, Eric J. Huang, Scott W. J. Mooney, Oliver B. Clarke, Sook Wah Yee, Kathleen M. Giacomini, Anthony A. Kossiakoff, Matthias Quick, Thomas Arnold, Filippo Mancia
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Multimodal decoding of human liver regeneration Nature (IF 64.8) Pub Date : 2024-05-01 K. P. Matchett, J. R. Wilson-Kanamori, J. R. Portman, C. A. Kapourani, F. Fercoq, S. May, E. Zajdel, M. Beltran, E. F. Sutherland, J. B. G. Mackey, M. Brice, G. C. Wilson, S. J. Wallace, L. Kitto, N. T. Younger, R. Dobie, D. J. Mole, G. C. Oniscu, S. J. Wigmore, P. Ramachandran, C. A. Vallejos, N. O. Carragher, M. M. Saeidinejad, A. Quaglia, R. Jalan, K. J. Simpson, T. J. Kendall, J. A. Rule, W. M
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Stereoselective amino acid synthesis by photobiocatalytic oxidative coupling Nature (IF 64.8) Pub Date : 2024-05-01 Tian-Ci Wang, Binh Khanh Mai, Zheng Zhang, Zhiyu Bo, Jiedong Li, Peng Liu, Yang Yang
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Structures of human γδ T cell receptor–CD3 complex Nature (IF 64.8) Pub Date : 2024-04-24 Weizhi Xin, Bangdong Huang, Ximin Chi, Yuehua Liu, Mengjiao Xu, Yuanyuan Zhang, Xu Li, Qiang Su, Qiang Zhou
Gamma delta (γδ) T cells, a unique T cell subgroup, are crucial in various immune responses and immunopathology1-3. The γδ T cell receptor (TCR), generated by γδ T cells, recognizes a diverse range of antigens independently of the major histocompatibility complex2. The γδ TCR associates with CD3 subunits, initiating T cell activation and holding great potential in immunotherapy4. Here, we report the
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High-performance fibre battery with polymer gel electrolyte Nature (IF 64.8) Pub Date : 2024-04-24 Chenhao Lu, Haibo Jiang, Xiangran Cheng, Jiqing He, Yao Long, Yingfan Chang, Xiaocheng Gong, Kun Zhang, Jiaxin Li, Zhengfeng Zhu, Jingxia Wu, Jiajia Wang, Yuanyuan Zheng, Xiang Shi, Lei Ye, Meng Liao, Xuemei Sun, Bingjie Wang, Peining Chen, Yonggang Wang, Huisheng Peng
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Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers Nature (IF 64.8) Pub Date : 2024-04-24 Stephane Ferretti, Jacques Hamon, Ruben de Kanter, Clemens Scheufler, Rita Andraos-Rey, Stephanie Barbe, Elisabeth Bechter, Jutta Blank, Vincent Bordas, Ernesta Dammassa, Andrea Decker, Noemi Di Nanni, Marion Dourdoigne, Elena Gavioli, Marc Hattenberger, Alisa Heuser, Christelle Hemmerlin, Jürgen Hinrichs, Grainne Kerr, Laurent Laborde, Isabel Jaco, Eloísa Jiménez Núñez, Hans-Joerg Martus, Cornelia
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Antisense oligonucleotide therapeutic approach for Timothy syndrome Nature (IF 64.8) Pub Date : 2024-04-24 Xiaoyu Chen, Fikri Birey, Min-Yin Li, Omer Revah, Rebecca Levy, Mayuri Vijay Thete, Noah Reis, Konstantin Kaganovsky, Massimo Onesto, Noriaki Sakai, Zuzana Hudacova, Jin Hao, Xiangling Meng, Seiji Nishino, John Huguenard, Sergiu P. Pașca
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Multi-project wafers for flexible thin-film electronics by independent foundries Nature (IF 64.8) Pub Date : 2024-04-24 Hikmet Çeliker, Wim Dehaene, Kris Myny
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Growth of diamond in liquid metal at 1 atm pressure Nature (IF 64.8) Pub Date : 2024-04-24 Yan Gong, Da Luo, Myeonggi Choe, Yongchul Kim, Babu Ram, Mohammad Zafari, Won Kyung Seong, Pavel Bakharev, Meihui Wang, In Kee Park, Seulyi Lee, Tae Joo Shin, Zonghoon Lee, Geunsik Lee, Rodney S. Ruoff