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Assembly and Disassembly of Supramolecular Hypervalent Iodine Macrocycles via Anion Coordination J. Org. Chem. (IF 3.6) Pub Date : 2024-05-14 Krishna Pandey, Samsul Arafin, Eli Jones, Yachu Du, Gajanan C. Kulkarni, Ain Uddin, Toby J. Woods, Kyle N. Plunkett
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Pyridinium Ylide-Mediated Diastereoselective Synthesis of Spirocyclopropanyl-pyrazolones via Cascade Michael/Substitution Reaction J. Org. Chem. (IF 3.6) Pub Date : 2024-05-14 Akanksha Kumari, Dhirajkumar Jitendrabhai Patanvadiya, Anshul Jain, Ranjan Patra, Manikandan Paranjothy, Nirmal K. Rana
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Quasi-Podands with 1,2,3-Triazole Rings from Bile Acid Derivatives: Synthesis, and Spectroscopic and Theoretical Studies J. Org. Chem. (IF 3.6) Pub Date : 2024-05-14 Anna Kawka, Hanna Koenig, Damian Nowak, Tomasz Pospieszny
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Electrochemical Reductive Cross-Coupling of Alkyl or Alkenyl Halides with gem-Difluoroalkenes J. Org. Chem. (IF 3.6) Pub Date : 2024-05-14 Hong Zhang, Zenghui Ye, Jiyuan Tang, Yanqi Wu, Xi Zhang, Weiyuan Ma, Zhajun Zhan, Fengzhi Zhang
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Palladium-Catalyzed Three-Component Cascade Carbonylation Reaction to Construct Benzofuran Derivatives J. Org. Chem. (IF 3.6) Pub Date : 2024-05-14 Ming Li, Shanmei Xu, Dong-Ping Chen, Fan Gao, Shun-Xi Li, Shuang-Xi Zhu, Yi-Feng Qiu, Zheng-Jun Quan, Xi-Cun Wang, Yong-Min Liang
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Synthesis of Benzo[e][1,4,3]oxathiazin-3-one 1-Oxides from NH-S-(2-Hydroxyaryl)sulfoximines J. Org. Chem. (IF 3.6) Pub Date : 2024-05-14 Kiruthika Periasamy, Pit van Bonn, Runa Tschekorsky Orloff, Nils Völcker, Qiulan Lu, Kari Rissanen, Carsten Bolm
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Synthesis of N2-trans-isosafrole-dG-adduct Bearing DNAs and the Bypass Studies with Human TLS Polymerases κ and η J. Org. Chem. (IF 3.6) Pub Date : 2024-05-13 Siddharam Shivappa Bagale, Priyanka U. Deshmukh, Shailesh B. Lad, Akhil Sudarsan, Sruthi Sudhakar, Soumyadeep Mandal, Kiran Kondabagil, P. I. Pradeepkumar
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Synthesis of Perdeuterated Alkyl Amines/Amides with Pt/C as Catalyst under Mild Conditions J. Org. Chem. (IF 3.6) Pub Date : 2024-05-13 Hong-Hai Zhang, Meng-Zhe Chen, Xinbin Yu, Peter V. Bonnesen, Zili Wu, Hsin-Lung Chen, Hugh O’Neill
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Synthesis of Branch-Type 3-Allylindoles from N-Alkyl-N-cinnamyl-2-ethynylaniline Derivatives Using π–Allylpalladium Chloride Complex as a Catalyst J. Org. Chem. (IF 3.6) Pub Date : 2024-05-10 Kohei Watanabe, Keita Nakano, Hayato Sato, Toshiki Yamaoka, Yasushi Yoshida, Ryo Takita, Yoshio Kasashima, Masami Sakamoto, Takashi Mino
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Carbene-Catalyzed Atroposelective Construction of Chiral Diaryl Ethers J. Org. Chem. (IF 3.6) Pub Date : 2024-05-13 Yuheng Liu, Lutong Yuan, Linlong Dai, Qiaohong Zhu, Guofu Zhong, Xiaofei Zeng
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Visible-Light-Promoted Radical Cascade Cyclization of 2-Vinyl Benzimidazoles: Access to Benzo[4,5]imidazo[1,2-b]isoquinolin- 11(6H)-ones J. Org. Chem. (IF 3.6) Pub Date : 2024-05-13 Yao-Tian Wang, Mai Zhang, Zhi-Xing Liu, Yu-Xin Wu, Qian Yan, Cheng-Liang Liu, Jiang-Sheng Li, Zhi-Wei Li, Han-Wen Liu, Wen-Sheng Li
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ortho-Alkynyl Benzyl Alcohols as C6 Synthons in Regioselective Construction of Polysubstituted Naphthalenes J. Org. Chem. (IF 3.6) Pub Date : 2024-05-13 Xuemei Wei, Tao Cai, Zhebing Zhang, Yanjuan Luo, Tianbo Shang, Hualiang Shen, Huiting Xu, Lemao Yu, Xiang Luo, Guoqi Yu, Runpu Shen
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Photoredox Synthesis of Silicon-Containing Isoindolin-1-ones and Deuterated Analogues Through Hydrosilylation and Deuterium-silylation J. Org. Chem. (IF 3.6) Pub Date : 2024-05-10 Guo-Qin Wang, Yue Zhang, Yuan-Xia Zhou, Dan Yang, Pan Han, Lin-Hai Jing, Kai Tang
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Synthesis of 2-(Trifluoromethyl)-[1,2,4]triazolo[5,1-a]isoquinoline via Cycloaddition of C,N-Cyclic Azomethine Imine with CF3CN J. Org. Chem. (IF 3.6) Pub Date : 2024-05-09 Zhezuo Chen, Shouxiong Chen, Zhanyan Qiu, Bo Lin, Yunfei Yao, Fafu Yang, Zhiqiang Weng
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Exploring a Non-Comfort Zone: Central Chirality-Generating Macrocyclizations J. Org. Chem. (IF 3.6) Pub Date : 2024-05-10 Kuan Zheng, Ran Hong
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An Expedient Approach to Access Phenalenones via Unconventional [1,2]-Phospha-Brook Rearrangement/Carbonyl Migration J. Org. Chem. (IF 3.6) Pub Date : 2024-05-10 Amjad Ali, Chandana Behera, Ravi P. Singh
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Deoxygenative Hetero- and Carbofunctionalizations of Diarylketones J. Org. Chem. (IF 3.6) Pub Date : 2024-05-10 Moriaki Sakihara, Miki B. Kurosawa, Mizuho Watanabe, Shuhei Shimoyama, Junichiro Yamaguchi
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Substrate-Controlled Divergent Synthesis of Benzimidazole-Fused Quinolines and Spirocyclic Benzimidazole-Fused Isoindoles J. Org. Chem. (IF 3.6) Pub Date : 2024-05-09 Ying-Ti Huang, Wan-Wen Huang, Yi-Ting Huang, Hong-Ren Chen, Indrajeet J. Barve, Chung-Ming Sun
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Self-Aggregation, Enhanced Guest-Binding Behavior, and Anion-Induced Agglutination of Cyclophane Dimers Linked with Florescent Perylene Diimide J. Org. Chem. (IF 3.6) Pub Date : 2024-05-09 Osamu Hayashida, Yuya Araki, Takaaki Miyazaki
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Visible-Light-Promoted C3-Sulfenylindoles with Arylsulfonyl Chlorides via Electron Donor–Acceptor Complex J. Org. Chem. (IF 3.6) Pub Date : 2024-05-09 Ziqian Xue, Wenjing Yang, Qiuzhan Huang, Cong-Ying Zhou, Zhen Guo
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Copper-Catalyzed One-Pot Synthesis of Thiazolidin-2-imines J. Org. Chem. (IF 3.6) Pub Date : 2024-05-09 Leandros P. Zorba, Ioannis Stylianakis, Nikolaos Tsoureas, Antonios Kolocouris, Georgios C. Vougioukalakis
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Copper/O2-Mediated Oxidative C–C Activation of Nitriles for Selective Acylation-Bromination of Anilines J. Org. Chem. (IF 3.6) Pub Date : 2024-05-08 Wei-Yu Shi, Song-Lin Zhang
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Lewis Acid-Catalyzed Formal [4 + 2] Reaction of Alkynyl Sulfides and 2-Pyrones To Access Polysubstituted Aryl Sulfides J. Org. Chem. (IF 3.6) Pub Date : 2024-05-08 Bin Huang, Donghui Xing, Huanfeng Jiang, Liangbin Huang
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Rational Design of a Highly Sensitive Carboxylesterase Probe and Its Application in High-Throughput Screening for Uncovering Carboxylesterase Inhibitors J. Org. Chem. (IF 3.6) Pub Date : 2024-05-08 Kexin Wang, Ruoxi Wang, Zihui Yan, Yi Li, Yangchen Shi, Jing-Yuan Ge, Yang Bai, Zhongyan Chen, Lei Zhang
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Optimizing the Synthesis Strategy of the Chlorinated Chain Characteristic to the Enacyloxin Series Using Models J. Org. Chem. (IF 3.6) Pub Date : 2024-05-06 Orane Christin, Emmanuel Roulland
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Pd-Catalyzed Miyaura Borylation and Telescopic Borylation/Suzuki–Miyaura Cross-Coupling Processes in Deep-Eutectic Solvents J. Org. Chem. (IF 3.6) Pub Date : 2024-05-08 Francesco D’Amico, Costanza Papucci, Daniele Franchi, Gianna Reginato, Maurizio Taddei, Alessandro Mordini, Lorenzo Zani, Alessio Dessì, Massimo Calamante
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Effective In Situ Alkoxide Trapping by TMSX in the Presence of TPP Catalyst in Glycidol Acetal Rearrangements J. Org. Chem. (IF 3.6) Pub Date : 2024-05-08 Meera Johny, Goreti Rajendar
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α-Cleavage of 2,2-Diazido-2,3-dihydroinden-1-one in Solution and Cryogenic Matrices J. Org. Chem. (IF 3.6) Pub Date : 2024-05-08 Brandi James, H. Dushanee M. Sriyarathne, Upasana Banerjee, Wandana K. S. Henarath Mohottige, Ben Crabtree, Aliz León, Miao Hong, Javeria Tariq, Taha Alhayani, Manabu Abe, Bruce S. Ault, Anna D. Gudmundsdottir
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Purple Light-Promoted Coupling of Bromopyridines with Grignard Reagents via SET J. Org. Chem. (IF 3.6) Pub Date : 2024-05-08 Xingyu Lei, Yihan Wang, Shanshan Ma, Peng Jiao
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Flexible and Convergent Enantioselective Total Synthesis of (R)-Juglanaloids A and B: Two Phthalide Spiro Alkaloids with Potential Alzheimer’s Disease Inhibitory Activity J. Org. Chem. (IF 3.6) Pub Date : 2024-05-08 Ibrahim Khettar, Arianna Sinibaldi, Rosaria Schettini, Giorgio Gorini, Ayesha Siddiqa, Antonella Dentoni Litta, Francesco De Riccardis, Irene Izzo, Giorgio Della Sala
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Al(III)-Promoted Formation of All-Carbon Quaternary Centers from Aliphatic Tertiary Chlorides and Alkynyl Silanes J. Org. Chem. (IF 3.6) Pub Date : 2024-05-07 Paul Charki, Daniel S. Müller
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Synthesis of Macrolactone Core of ent-Formosalide A via Regioselective Ether Cyclization J. Org. Chem. (IF 3.6) Pub Date : 2024-05-07 Risa Mozumi, Keisuke Fukaya, Hina Ito, Tomomi Komatsu, Daisuke Urabe
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Sparteine Thiourea: The Synthesis of an N Chiral Bispidine-Quinolizidine-Derived Organocatalyst and Applications in Asymmetric Synthesis of Dihydropyrano[c]chromenes J. Org. Chem. (IF 3.6) Pub Date : 2024-05-07 Hexin Sun, Lin Huang, Jianhui Huang
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EMM-Promoted Pd-Catalyzed Solid State Intramolecular Heck-Type Cyclization/Boronation and Suzuki Couplings: Access to Functionalized Indolines J. Org. Chem. (IF 3.6) Pub Date : 2024-05-06 Yuwei Jia, Hui Wang, Jintao Guo, Feng Zhang, Lizhi Zhang, Xinjin Li, Yan Zhao, Xingliang Bao, Qing Liu, Xiaowei Li, Hui Liu
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An Alternative Approach to Synthesize Sildenafil via Improved Copper-Catalyzed Cyclization J. Org. Chem. (IF 3.6) Pub Date : 2024-05-06 Abdullajon Odilov, Xudong Gong, Hongjian Qin, Emmanuel Mintah Bonku, Fuqiang Zhu, Feipu Yang, Jingshan Shen
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Mechanistic Studies on Bromocyclization of Unsaturated Thioester by Density Functional Theory and Experiment J. Org. Chem. (IF 3.6) Pub Date : 2024-05-06 Rinako Saegusa, Miari Kurihara, Hiroki Shigehisa
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Lithium Bromide-Promoted Formal C(sp3)–H Bond Insertion Reactions of β-Carbonyl Esters with Sulfoxonium Ylides to Synthesize 1,4-Dicarbonyl Compounds J. Org. Chem. (IF 3.6) Pub Date : 2024-05-04 Hailin Guo, Yuhao Ding, Jingwen Fan, Zhiyong Li, Guolin Cheng
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Modular Approach to Highly Substituted 3-Methylpyridones J. Org. Chem. (IF 3.6) Pub Date : 2024-05-03 Yan Zhang, Hui Chen, Lianyou Zheng, Lingling Shi, Xin Che, Zhuoqi Zhang, Jinbao Xiang
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Access to 2-Alkenyl-furans via a Cascade of Pd-Catalyzed Cyclization/Coupling Followed by Oxidative Aromatization with DDQ J. Org. Chem. (IF 3.6) Pub Date : 2024-05-03 Bartosz Bisek, Wojciech Chaładaj
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Deciphering the Origin of Regioselectivity in Ru(II)-Catalyzed C–H Annulation of N-Chlorobenzamides with 1,3-Diynes J. Org. Chem. (IF 3.6) Pub Date : 2024-05-03 Janavi Rajput, Arijit Ghosh, Amit B. Pawar, Bhaskar Mondal
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Elucidating the Mechanism of Tetrahydrofuran-Diol Formation through Os(VI)-Catalyzed Oxidative Cyclization of 5,6-Dihydroxyalkenes Ligated by Citric Acid J. Org. Chem. (IF 3.6) Pub Date : 2024-05-03 Aqeel A. Hussein, Nadhir N. A. Jafar, Yumiao Ma
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Merging Cobalt-Catalyzed C–H Activation with the Mannich Reaction: A Modular Approach to α-Substituted N-Sulfonyl Amines J. Org. Chem. (IF 3.6) Pub Date : 2024-05-03 Oluwaseun A. Olu-Igbiloba, Helmut Sitzmann, Georg Manolikakes
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Cascade Sequence of Photooxygenation–Epoxidation for the Flow Synthesis of Epoxy Alcohols J. Org. Chem. (IF 3.6) Pub Date : 2024-05-03 Ji Eun Kim, Go Eun Son, Hyo Jin Lim, Yea Seul Jang, Chan Ho Song, Chan Pil Park
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Cobalt(II)-Catalyzed Synthesis of γ-Diketones from Aryl Alkenes and Its Utilization in the Synthesis of Various Heterocyclic Compounds J. Org. Chem. (IF 3.6) Pub Date : 2024-05-03 Subham Sau, Krishna Mohan Das, Bijan Mondal, Arunabha Thakur
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Synthesis of Fused [1,2,3]-Triazoloheteroarenes via Intramolecular Azo Annulation of N-Tosylhydrazones Catalyzed by 1,8-Diaza-bicyclo[5.4.0]undec-7-ene J. Org. Chem. (IF 3.6) Pub Date : 2024-05-03 Orume J. Edirin, Jesse D. Carrick
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Construction of 3-Methyl-2-Substituted Benzo[b]furans and 3-Methyl-2-Substituted Benzo[b]thiophenes Using Solid Calcium Carbide as a Substitute for Gaseous Acetylene J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Zhiqiang Wang, Zhenrong Liu, Ting Shao, Zheng Li
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Regioselective Propargylic Suzuki–Miyaura Coupling by SciPROP-Iron Catalyst J. Org. Chem. (IF 3.6) Pub Date : 2024-04-29 Siming Lu, Ryosuke Agata, Satsuki Nomura, Hiroshi Matsuda, Katsuhiro Isozaki, Masaharu Nakamura
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Chemoenzymatic Dynamic Kinetic Resolution Protocol with an Immobilized Oxovanadium as a Racemization Catalyst J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Jiarui Chen, Lingqin Min, Fanxu Meng, Yiwen Fu, Junhong Liu, Yuanyuan Zhang
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Structure–Photoreactivity Studies of BODIPY Photocages: Limitations of the Activation Barrier for Optimizing Photoreactions J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Komadhie C. Dissanayake, Ding Yuan, Arthur H. Winter
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One-Carbon Homologation of Knoevenagel Adducts: Enantioselective Access to Benzhydryl Derivatives J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Julien Janssens, Madeline De Roose, Alexis Jacquemin, Thomas Vanhosmael, Arnaud Delbrassinne, Laurent Collard, Raphaël Robiette
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Carbene-Catalyzed [4+2] Cycloaddition of Cyclobutenones and Isatins for Quick Access to Chiral Chlorine-Containing Spirocyclic δ-Lactones J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Bin Liu, Xian Zhou, Qinqin Liu, Zaihui Yang, Yuanhu Mao, Qing He, Tianyuan Zhang, Xiangkai Kong, Jiquan Zhang, Weike Liao, Lei Tang
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Asymmetric Additions Empowered by OrganoCatalysts, Metal Catalysts, and Deep Natural Eutectic Solvents (NADES) J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Elisabete P. Carreiro, Gesine J. Hermann, Hans-Jürgen Federsel, Anthony J. Burke
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Transesterification of Dimethyl Carbonate with Ethanol Catalyzed by Guanidine: A Theoretical Analysis J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Sina Gilassi, Serge Kaliaguine
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Synthesis of 2,3-Dialkyl-5-hydroxybenzofurans via a One-pot, Three-step Reaction Sequence of 2-Monosubstituted 1,3-Diketones and 1,4-Benzoquinones J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Qing Dong, Yu-Huan Yang, Xue-Jiao Lv, Jia-Hui Liu, Yan-Kai Liu
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Tetrakispyrazolylethene: Protonation-Induced Emission J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Yuta Takemasa, Kyoko Nozaki
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Organoselenium-Catalyzed C2,3-Diarylation of N–H Indoles J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Yingying Zhang, Xiaoxiang Zhang, Junqiu Liao, Zongwu Wei, Zhuan Zhang, Taoyuan Liang
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Photoinduced Palladium-Catalyzed Radical Heck-Type Coupling of Cyclobutanone Oxime Esters with Vinyl Arenes J. Org. Chem. (IF 3.6) Pub Date : 2024-05-02 Sen Yang, Sha-Sha Cai, Jun-Hua Li, Ming Chen
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High-Pressure Promoted Nazarov-like Electrocyclization Enables Access to trans-4,5-Diamino-cyclopent-2-enones Bearing Electron-Poor Anilines J. Org. Chem. (IF 3.6) Pub Date : 2024-05-01 Lídia A. S. Cavaca, Tiago M. P. Santos, Joao M. J. M. Ravasco, Rafael F. A. Gomes, Carlos A. M. Afonso
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Synthesis of 1-Benzyl-2,4-diarylimidazole through I2/CuI-Catalyzed Cyclization of Benzylamine and Hydrazone J. Org. Chem. (IF 3.6) Pub Date : 2024-05-01 Ting-Kang Lv, Si Chen, Yi-Xuan Lu, Bao-Hua Chen
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Tf2O-Mediated P(O)–N Bond Formation of Either P(O)–OH or P(O)–H Reagents with Multitype Amines J. Org. Chem. (IF 3.6) Pub Date : 2024-05-01 Da-Wei Shi, Hui-Qi Yue, Ming Li, Jie Liu, Chang-Cheng Wang, Shang-Dong Yang, Bin Yang