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Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids Cell Stem Cell (IF 23.9) Pub Date : 2024-05-15 Lan Dao, Zhen You, Lu Lu, Tianyang Xu, Avijite Kumer Sarkar, Hui Zhu, Miao Liu, Riccardo Calandrelli, George Yoshida, Pei Lin, Yifei Miao, Sarah Mierke, Srijan Kalva, Haining Zhu, Mingxia Gu, Sudhakar Vadivelu, Sheng Zhong, L. Frank Huang, Ziyuan Guo
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Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics Cell Stem Cell (IF 23.9) Pub Date : 2024-05-15 Suzan Stelloo, Maria Teresa Alejo-Vinogradova, Charlotte A.G.H. van Gelder, Dick W. Zijlmans, Marek J. van Oostrom, Juan Manuel Valverde, Lieke A. Lamers, Teja Rus, Paula Sobrevals Alcaraz, Tilman Schäfers, Cristina Furlan, Pascal W.T.C. Jansen, Marijke P.A. Baltissen, Katharina F. Sonnen, Boudewijn Burgering, Maarten A.F.M. Altelaar, Harmjan R. Vos, Michiel Vermeulen
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Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells Cell Stem Cell (IF 23.9) Pub Date : 2024-05-15 Paul V. Dellorusso, Melissa A. Proven, Fernando J. Calero-Nieto, Xiaonan Wang, Carl A. Mitchell, Felix Hartmann, Meelad Amouzgar, Patricia Favaro, Andrew DeVilbiss, James W. Swann, Theodore T. Ho, Zhiyu Zhao, Sean C. Bendall, Sean Morrison, Berthold Göttgens, Emmanuelle Passegué
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Breast cancer-on-chip for patient-specific efficacy and safety testing of CAR-T cells Cell Stem Cell (IF 23.9) Pub Date : 2024-05-15 Tengku Ibrahim Maulana, Claudia Teufel, Madalena Cipriano, Julia Roosz, Lisa Lazarevski, Francijna E. van den Hil, Lukas Scheller, Valeria Orlova, André Koch, Michael Hudecek, Miriam Alb, Peter Loskill
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity Cell (IF 64.5) Pub Date : 2024-05-15
Clinical trials have identified ARID1A mutations as enriched among patients who respond favorably to immune checkpoint blockade (ICB) in several solid…
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A vision for global eDNA-based monitoring in a changing world Cell (IF 64.5) Pub Date : 2024-05-15 Philip Francis Thomsen, Mads Reinholdt Jensen, Eva Egelyng Sigsgaard
Environmental DNA (eDNA) has opened promising avenues for establishing standardized, cost-efficient monitoring of biodiversity. However, comprehensive and systematic implementation is urgently needed to address the current biodiversity crisis. Here, we envision a global eDNA biomonitoring scheme, which could potentially revolutionize the understanding and conservation of life on Earth.
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In This Issue Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14
Proceedings of the National Academy of Sciences, Volume 121, Issue 20, May 2024.
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I’m worried I’ve been contacted by a predatory publisher — how do I find out? Nature (IF 64.8) Pub Date : 2024-05-15
Researchers frequently receive invitations to publish in journals that they might not have heard of. Nature asked two scientists how they would check whether a publication is legitimate.
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Forestry social science is failing the needs of the people who need it most Nature (IF 64.8) Pub Date : 2024-05-15
Rich nations’ fixation on forests as climate offsets has resulted in the needs of those who live in or make a living from these resources being ignored. A broader view and more collaboration between disciplines is required.
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Explaining novel scientific concepts to people whose technical acumen does not extend to turning it off, then turning it on again Nature (IF 64.8) Pub Date : 2024-05-15
Guided by the light.
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Neglecting sex and gender in research is a public-health risk Nature (IF 64.8) Pub Date : 2024-05-15 Sue Haupt, Cheryl Carcel, Robyn Norton
The data are clear: taking sex and gender into account in research and using that knowledge to change health care could benefit billions of people.
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How to kill the ‘zombie’ cells that make you age Nature (IF 64.8) Pub Date : 2024-05-15
Researchers are using new molecules, engineered immune cells and gene therapy to kill senescent cells and treat age-related diseases.
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2023 summer warmth unparalleled over the past 2,000 years Nature (IF 64.8) Pub Date : 2024-05-14 Jan Esper, Max Torbenson, Ulf Büntgen
Including an exceptionally warm Northern Hemisphere (NH) summer1,2, 2023 has been reported as the hottest year on record3-5. Contextualizing recent anthropogenic warming against past natural variability is nontrivial, however, because the sparse 19th century meteorological records tend to be too warm6. Here, we combine observed and reconstructed June-August (JJA) surface air temperatures to show that
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Africa’s lush tropical forests face a surprising threat: fire Nature (IF 64.8) Pub Date : 2024-05-14
Climate change and deforestation have increased the frequency of blazes in the humid forests of West and Central Africa.
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AI & robotics briefing: Why AI needs to see the ‘ugly’ side of science Nature (IF 64.8) Pub Date : 2024-05-14
The absence of negative results in the scientific literature is affecting AI tools trained on published data. Plus, why animals still outrun robots and AlphaFold gets major upgrade.
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Daily briefing: Amazing auroras are just a warm-up — more solar storms are coming Nature (IF 64.8) Pub Date : 2024-05-14
The upcoming solar maximum means more and bigger solar storms to come. Plus, how to decarbonise the workhorse of fossil fuel production: oil refineries.
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An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis Cell (IF 64.5) Pub Date : 2024-05-14 Donna M. Poscablo, Atesh K. Worthington, Stephanie Smith-Berdan, Marcel G.E. Rommel, Bryce A. Manso, Reheman Adili, Lydia Mok, Roman E. Reggiardo, Taylor Cool, Raana Mogharrab, Jenna Myers, Steven Dahmen, Paloma Medina, Anna E. Beaudin, Scott W. Boyer, Michael Holinstat, Vanessa D. Jonsson, E. Camilla Forsberg
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GAGE-seq concurrently profiles multiscale 3D genome organization and gene expression in single cells Nat. Genet. (IF 30.8) Pub Date : 2024-05-14 Tianming Zhou, Ruochi Zhang, Deyong Jia, Raymond T. Doty, Adam D. Munday, Daniel Gao, Li Xin, Janis L. Abkowitz, Zhijun Duan, Jian Ma
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Inseparable RNA binding and chromatin modification activities of a nucleosome-interacting surface in EZH2 Nat. Genet. (IF 30.8) Pub Date : 2024-05-14 Emma H. Gail, Evan Healy, Sarena F. Flanigan, Natasha Jones, Xiao Han Ng, Michael Uckelmann, Vitalina Levina, Qi Zhang, Chen Davidovich
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Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of clonal hematopoiesis Nat. Genet. (IF 30.8) Pub Date : 2024-05-14 Nicholas Bernstein, Michael Spencer Chapman, Kudzai Nyamondo, Zhenghao Chen, Nicholas Williams, Emily Mitchell, Peter J. Campbell, Robert L. Cohen, Jyoti Nangalia
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Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction Nat. Genet. (IF 30.8) Pub Date : 2024-05-13 Guochong Jia, Jie Ping, Xingyi Guo, Yaohua Yang, Ran Tao, Bingshan Li, Stefan Ambs, Mollie E. Barnard, Yu Chen, Montserrat Garcia-Closas, Jian Gu, Jennifer J. Hu, Dezheng Huo, Esther M. John, Christopher I. Li, James L. Li, Katherine L. Nathanson, Barbara Nemesure, Olufunmilayo I. Olopade, Tuya Pal, Michael F. Press, Maureen Sanderson, Dale P. Sandler, Xiao-Ou Shu, Melissa A. Troester, Song Yao, Prisca
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Phase separation-competent FBL promotes early pre-rRNA processing and translation in acute myeloid leukaemia Nat. Cell Biol. (IF 21.3) Pub Date : 2024-05-14 Lin Yang, Zhaoru Zhang, Penglei Jiang, Delin Kong, Zebin Yu, Danrong Shi, Yingli Han, Ertuo Chen, Weiyan Zheng, Jie Sun, Yanmin Zhao, Yi Luo, Jimin Shi, Hangping Yao, He Huang, Pengxu Qian
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A milestone method to make natural killer T cells Nat. Biotechnol. (IF 46.9) Pub Date : 2024-05-14 Leonid S. Metelitsa
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Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method Nat. Biotechnol. (IF 46.9) Pub Date : 2024-05-14 Yan-Ruide Li, Yang Zhou, Jiaji Yu, Yu Jeong Kim, Miao Li, Derek Lee, Kuangyi Zhou, Yuning Chen, Yichen Zhu, Yu-Chen Wang, Zhe Li, Yanqi Yu, Zachary Spencer Dunn, Wenbin Guo, Xinjian Cen, Tiffany Husman, Aarushi Bajpai, Adam Kramer, Matthew Wilson, Ying Fang, Jie Huang, Shuo Li, Yonggang Zhou, Yuchong Zhang, Zoe Hahn, Enbo Zhu, Feiyang Ma, Calvin Pan, Aldons J. Lusis, Jin J. Zhou, Christopher S. Seet
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Protein-adaptive differential scanning fluorimetry using conformationally responsive dyes Nat. Biotechnol. (IF 46.9) Pub Date : 2024-05-14 Taiasean Wu, Joshua C. Yu, Arundhati Suresh, Zachary J. Gale-Day, Matthew G. Alteen, Amanda S. Woo, Zoe Millbern, Oleta T. Johnson, Emma C. Carroll, Carrie L. Partch, Denis Fourches, Nelson R. Vinueza, David J. Vocadlo, Jason E. Gestwicki
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Real-world plastic-waste success stories can help to boost global treaty Nature (IF 64.8) Pub Date : 2024-05-14
Letter to the Editor
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Interpersonal therapy can be an effective tool against the devastating effects of loneliness Nature (IF 64.8) Pub Date : 2024-05-14
Letter to the Editor
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Inequality is bad — but that doesn’t mean the rich are Nature (IF 64.8) Pub Date : 2024-05-14
Letter to the Editor
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Balls of lightning and flames from the sky: can science explain? Nature (IF 64.8) Pub Date : 2024-05-14
Snippets from Nature’s past.
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Standardized metadata for biological samples could unlock the potential of collections Nature (IF 64.8) Pub Date : 2024-05-14
Letter to the Editor
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Why mathematics is set to be revolutionized by AI Nature (IF 64.8) Pub Date : 2024-05-14
Cheap data and the absence of coincidences make maths an ideal testing ground for AI-assisted discovery — but only humans will be able to tell good conjectures from bad ones.
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How does ChatGPT ‘think’? Psychology and neuroscience crack open AI large language models Nature (IF 64.8) Pub Date : 2024-05-14
Researchers are striving to reverse-engineer artificial intelligence and scan the ‘brains’ of LLMs to see what they are doing, how and why.
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The phenomenon of genomic imprinting was discovered 40 years ago Nature (IF 64.8) Pub Date : 2024-05-14 Anne C. Ferguson-Smith, Marisa S. Bartolomei
Landmark 1984 experiments gave rise to a new epigenetics concept.
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How men evolved to care for babies — before society got in the way Nature (IF 64.8) Pub Date : 2024-05-14
An exploration of the evolution of male nurturing shows why, unlike fathers among other great apes, human dads are biologically wired to be hands-on parents.
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A DARPA-like agency could boost EU innovation — but cannot come at the expense of existing schemes Nature (IF 64.8) Pub Date : 2024-05-14
If Europe wants to create a high-risk, high-reward research body, it needs grass-roots backing.
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Mega study charts how genetic variants affect metabolism Nature (IF 64.8) Pub Date : 2024-05-14
The discovery of hundreds of genomic regions linked with metabolism promises to improve our understanding of metabolic diseases.
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Plasmid targeting and destruction by the DdmDE bacterial defence system Nature (IF 64.8) Pub Date : 2024-05-13 Jack P. K. Bravo, Delisa A. Ramos, Rodrigo Fregoso Ocampo, Caiden Ingram, David W. Taylor
While eukaryotic Argonautes play a pivotal role in post-transcriptional gene regulation through nucleic acid cleavage, some short prokaryotic Argonaute variants (pAgos) rely on auxiliary nuclease factors for efficient foreign DNA degradation (1). Here, we elucidate the activation pathway of the DNA Defense Module DdmDE system, which rapidly eliminates small, multicopy plasmids from Vibrio cholerae
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Dazzling auroras are just a warm-up as more solar storms are likely, scientists say Nature (IF 64.8) Pub Date : 2024-05-13
Nature talks to physicists about what to expect in the next months and beyond as the Sun hits its 'maximum'.
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Brain-reading device is best yet at decoding ‘internal speech’ Nature (IF 64.8) Pub Date : 2024-05-13
Technology that enables researchers to interpret brain signals could one day allow people to talk using only their thoughts.
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Human embryos embrace asymmetry to form the body Nature (IF 64.8) Pub Date : 2024-05-13
The cells generated by the very first division of the fertilized egg make a lopsided contribution to the body’s organs and tissues.
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Daily briefing: Internet use seems to boost well-being Nature (IF 64.8) Pub Date : 2024-05-10
A survey of people in 168 countries finds that Internet use might boost life satisfaction and sense of purpose. Plus, what a Neanderthal’s Mona-Lisa smile tells us about ourselves and how the cauliflower got its whorls.
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Daily briefing: A millimetre of brain in spectacular detail Nature (IF 64.8) Pub Date : 2024-05-10
Google scientists have modelled a tiny fragment of the human brain at nanoscale resolution. Plus, a bold proposal to limit extreme wealth.
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SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23 Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Danilo Segovia, Dexter W. Adams, Nickolas Hoffman, Polona Safaric Tepes, Tse-Luen Wee, Paolo Cifani, Leemor Joshua-Tor, Adrian R. Krainer
SRSF1 is the founding member of the SR protein family. It is required—interchangeably with other SR proteins—for pre-mRNA splicing in vitro, and it regulates various alternative splicing events. Dysregulation of SRSF1 expression contributes to cancer and other pathologies. Here, we characterized SRSF1’s interactome using proximity labeling and mass spectrometry. This approach yielded 190 proteins enriched
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Lipid-derived electrophiles inhibit the function of membrane channels during ferroptosis Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Antonius T. M. Van Kessel, Gonzalo Cosa
The therapeutic targeting of ferroptosis requires full understanding of the molecular mechanism of this regulated cell death pathway. While lipid-derived electrophiles (LDEs), including 4-hydroxy-2-nonenal (4-HNE), are important biomarkers of ferroptosis, a functional role for these highly reactive species in ferroptotic cell death execution has not been established. Here, through mechanistic characterization
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Requirements for the biogenesis of [2Fe-2S] proteins in the human and yeast cytosol Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Joseph J. Braymer, Oliver Stehling, Martin Stümpfig, Ralf Rösser, Farah Spantgar, Catharina M. Blinn, Ulrich Mühlenhoff, Antonio J. Pierik, Roland Lill
The biogenesis of iron–sulfur (Fe/S) proteins entails the synthesis and trafficking of Fe/S clusters, followed by their insertion into target apoproteins. In eukaryotes, the multiple steps of biogenesis are accomplished by complex protein machineries in both mitochondria and cytosol. The underlying biochemical pathways have been elucidated over the past decades, yet the mechanisms of cytosolic [2Fe-2S]
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Dichotomous dynamics of magnetic monopole fluids Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Chun-Chih Hsu, Hiroto Takahashi, Fabian Jerzembeck, Jahnatta Dasini, Chaia Carroll, Ritika Dusad, Jonathan Ward, Catherine Dawson, Sudarshan Sharma, Graeme M. Luke, Stephen J. Blundell, Claudio Castelnovo, Jonathan N. Hallén, Roderich Moessner, J. C. Séamus Davis
A recent advance in the study of emergent magnetic monopoles was the discovery that monopole motion is restricted to dynamical fractal trajectories [J. N. Hallén et al. , Science 378 , 1218 (2022)], thus explaining the characteristics of magnetic monopole noise spectra [R. Dusad et al., Nature 571 , 234 (2019); A. M. Samarakoon et al. , Proc. Natl. Acad. Sci. U.S.A. 119 , e2117453119 (2022)]. Here
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Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 John R. Ferrarone, Jerin Thomas, Arun M. Unni, Yuxiang Zheng, Michal J. Nagiec, Eric E. Gardner, Oksana Mashadova, Kate Li, Nikos Koundouros, Antonino Montalbano, Meer Mustafa, Lewis C. Cantley, John Blenis, Neville E. Sanjana, Harold Varmus
The tumor suppressor LKB1 is a serine/threonine protein kinase that is frequently mutated in human lung adenocarcinoma (LUAD). LKB1 regulates a complex signaling network that is known to control cell polarity and metabolism; however, the pathways that mediate the tumor-suppressive activity of LKB1 are incompletely defined. To identify mechanisms of LKB1-mediated growth suppression, we developed a spheroid-based
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A fungal protein organizes both glycogen and cell wall glucans Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Liza Loza, Tamara L. Doering
Glycogen is a glucose storage molecule composed of branched α-1,4-glucan chains, best known as an energy reserve that can be broken down to fuel central metabolism. Because fungal cells have a specialized need for glucose in building cell wall glucans, we investigated whether glycogen is used for this process. For these studies, we focused on the pathogenic yeast Cryptococcus neoformans , which causes
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Dark continuous noise from mutant G90D-rhodopsin predominantly underlies congenital stationary night blindness Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Zuying Chai, Yaqing Ye, Daniel Silverman, Kasey Rose, Alana Madura, Randall R. Reed, Jeannie Chen, King-Wai Yau
Congenital stationary night blindness (CSNB) is an inherited retinal disease that causes a profound loss of rod sensitivity without severe retinal degeneration. One well-studied rhodopsin point mutant, G90D-Rho, is thought to cause CSNB because of its constitutive activity in darkness causing rod desensitization. However, the nature of this constitutive activity and its precise molecular source have
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Bacterial lifestyle shapes pangenomes Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Anna E. Dewar, Chunhui Hao, Laurence J. Belcher, Melanie Ghoul, Stuart A. West
Pangenomes vary across bacteria. Some species have fluid pangenomes, with a high proportion of genes varying between individual genomes. Other species have less fluid pangenomes, with different genomes tending to contain the same genes. Two main hypotheses have been suggested to explain this variation: differences in species’ bacterial lifestyle and effective population size. However, previous studies
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Identification and characterization of a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Priscila M. S. Castanha, Patrick J. McEnaney, Yongseok Park, Anthea Bouwer, Elton J. F. Chaves, Roberto D. Lins, Nicholas G. Paciaroni, Paige Dickson, Graham Carlson, Marli T. Cordeiro, Tereza Magalhaes, Jodi Craigo, Ernesto T. A. Marques, Thomas Kodadek, Donald S. Burke
Antigenic similarities between Zika virus (ZIKV) and other flaviviruses pose challenges to the development of virus-specific diagnostic tools and effective vaccines. Starting with a DNA-encoded one-bead-one-compound combinatorial library of 508,032 synthetic, non-natural oligomers, we selected and characterized small molecules that mimic ZIKV epitopes. High-throughput fluorescence-activated cell sorter-based
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Microbes vary strategically in their metalation of mononuclear enzymes Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Sanjay Kumar Rohaun, Ramakrishnan Sethu, James A. Imlay
Studies have determined that nonredox enzymes that are cofactored with Fe(II) are the most oxidant-sensitive targets inside Escherichia coli . These enzymes use Fe(II) cofactors to bind and activate substrates. Because of their solvent exposure, the metal can be accessed and oxidized by reactive oxygen species, thereby inactivating the enzyme. Because these enzymes participate in key physiological
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ZEPPI: Proteome-scale sequence-based evaluation of protein–protein interaction models Proc. Natl. Acad. Sci. U.S.A. (IF 11.1) Pub Date : 2024-05-14 Haiqing Zhao, Donald Petrey, Diana Murray, Barry Honig
We introduce ZEPPI (Z-score Evaluation of Protein–Protein Interfaces), a framework to evaluate structural models of a complex based on sequence coevolution and conservation involving residues in protein–protein interfaces. The ZEPPI score is calculated by comparing metrics for an interface to those obtained from randomly chosen residues. Since contacting residues are defined by the structural model
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The first two blastomeres contribute unequally to the human embryo Cell (IF 64.5) Pub Date : 2024-05-13 Sergi Junyent, Maciej Meglicki, Roman Vetter, Rachel Mandelbaum, Catherine King, Ekta M. Patel, Lisa Iwamoto-Stohl, Clare Reynell, Dong-Yuan Chen, Patrizia Rubino, Nabil Arrach, Richard J. Paulson, Dagmar Iber, Magdalena Zernicka-Goetz
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Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor Cell (IF 64.5) Pub Date : 2024-05-13 Jinjia Zhang, Junhong Li, Yongqiang Hou, Yao Lin, Hao Zhao, Yiran Shi, Kaiyun Chen, Cheng Nian, Jiayu Tang, Lei Pan, Yunzhi Xing, Huan Gao, Bingying Yang, Zengfang Song, Yao Cheng, Yue Liu, Min Sun, Yueyue Linghu, Jiaxin Li, Haitao Huang, Dawang Zhou
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Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin Cell (IF 64.5) Pub Date : 2024-05-13 Carlos Sacristan, Kumiko Samejima, Lorena Andrade Ruiz, Moonmoon Deb, Maaike L.A. Lambers, Adam Buckle, Chris A. Brackley, Daniel Robertson, Tetsuya Hori, Shaun Webb, Robert Kiewisz, Tristan Bepler, Eloïse van Kwawegen, Patrik Risteski, Kruno Vukušić, Iva M. Tolić, Thomas Müller-Reichert, Tatsuo Fukagawa, Nick Gilbert, Davide Marenduzzo, Geert J.P.L. Kops
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Tackling debt, biodiversity loss, and climate change Science (IF 56.9) Pub Date : 2024-05-10 Elizabeth C. Losos, Alexander Pfaff, Stuart L. Pimm
At the United Nations climate conference in late 2023, multilateral development banks and environmental institutions committed to raising the number, size, types, and effectiveness of funding mechanisms that support developing countries to address the interconnected crises of debt, climate, and biodiversity. A “Task Force on Sustainability-Linked Sovereign Financing for Nature and Climate” will convene
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Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes Nat. Genet. (IF 30.8) Pub Date : 2024-05-13 Minsoo Kim, Alexander N. Gorelick, Ignacio Vàzquez-García, Marc J. Williams, Sohrab Salehi, Hongyu Shi, Adam C. Weiner, Nick Ceglia, Tyler Funnell, Tricia Park, Sonia Boscenco, Ciara H. O’Flanagan, Hui Jiang, Diljot Grewal, Cerise Tang, Nicole Rusk, Payam A. Gammage, Andrew McPherson, Sam Aparicio, Sohrab P. Shah, Ed Reznik
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Integrating population genetics, stem cell biology and cellular genomics to study complex human diseases Nat. Genet. (IF 30.8) Pub Date : 2024-05-13 Nona Farbehi, Drew R. Neavin, Anna S. E. Cuomo, Lorenz Studer, Daniel G. MacArthur, Joseph E. Powell
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Harnessing clonal gametes in hybrid crops to engineer polyploid genomes Nat. Genet. (IF 30.8) Pub Date : 2024-05-13 Yazhong Wang, Roven Rommel Fuentes, Willem M. J. van Rengs, Sieglinde Effgen, Mohd Waznul Adly Mohd Zaidan, Rainer Franzen, Tamara Susanto, Joiselle Blanche Fernandes, Raphael Mercier, Charles J. Underwood