-
Glucagon‐like peptide‐1 receptor agonists: a narrative review of clinical pharmacology and implications for peri‐operative practice Anaesthesia (IF 10.7) Pub Date : 2024-05-14 David A. Milder, Tamara Y. Milder, Sophie S. Liang, Peter C.A. Kam
SummaryBackgroundGlucagon‐like peptide‐1 receptor agonists are used increasingly in the management of patients living with type 2 diabetes mellitus and obesity. In patients using glucagon‐like peptide‐1 receptor agonists, a key concern in the peri‐operative period is the increased risk of pulmonary aspiration due to delayed gastric emptying. This review provides an overview of the pharmacodynamic and
-
The association of withholding or continuing angiotensin‐converting enzyme inhibitors or angiotensin 2 receptor blockers on acute kidney injury after non‐cardiac surgery Anaesthesia (IF 10.7) Pub Date : 2024-05-14 Jisun Choi, Dae Kyun Ryu, Seunghyeon Woo, Jeayoun Kim, Seungwon Lee, Boram Park, Kyeongman Jeon, MiHye Park
SummaryBackgroundWithholding or continuing angiotensin‐converting enzyme inhibitors or angiotensin 2 receptor blockers peri‐operatively in non‐cardiac surgery remains controversial as they may result in intra‐operative hypotension and postoperative organ damage.MethodsWe included patients prescribed angiotensin‐converting enzyme inhibitors or angiotensin 2 receptor blockers who underwent surgical procedures
-
The prevalence of chronic pain in children and adolescents: a systematic review update and meta-analysis. Pain (IF 7.4) Pub Date : 2024-05-14 Christine T Chambers, Justine Dol, Perri R Tutelman, Charlotte L Langley, Jennifer A Parker, Brittany T Cormier, Gary J Macfarlane, Gareth T Jones, Darlene Chapman, Nicole Proudfoot, Amy Grant, Justina Marianayagam
Chronic pain, defined as persistent or recurring pain or pain lasting longer than 3 months, is a common childhood problem. The objective of this study was to conduct an updated systematic review and meta-analysis on the prevalence of chronic pain (ie, overall, headache, abdominal pain, back pain, musculoskeletal pain, multisite/general pain, and other) in children and adolescents. EMBASE, PubMed, CINAHL
-
Data-driven identification of distinct pain drawing patterns and their association with clinical and psychological factors: a study of 21,123 patients with spinal pain. Pain (IF 7.4) Pub Date : 2024-05-14 Natalie Hong Siu Chang, Casper Nim, Steen Harsted, James J Young, Søren O'Neill
The variability in pain drawing styles and analysis methods has raised concerns about the reliability of pain drawings as a screening tool for nonpain symptoms. In this study, a data-driven approach to pain drawing analysis has been used to enhance the reliability. The aim was to identify distinct clusters of pain patterns by using latent class analysis (LCA) on 46 predefined anatomical areas of a
-
Use of patient-reported global assessment measures in clinical trials of chronic pain treatments: ACTTION systematic review and considerations. Pain (IF 7.4) Pub Date : 2024-05-14 Dale J Langford, Remington P Mark, Fallon O France, Mahd Nishtar, Meghan Park, Sonia Sharma, Isabel C Shklyar, Thomas J Schnitzer, Philip G Conaghan, Dagmar Amtmann, Bryce B Reeve, Dennis C Turk, Robert H Dworkin, Jennifer S Gewandter
Establishing clinically meaningful changes in pain experiences remains important for clinical trials of chronic pain treatments. Regulatory guidance and pain measurement initiatives have recommended including patient-reported global assessment measures (eg, Patient-Global Impression of Change [PGIC]) to aid interpretation of within-patient differences in domain-specific clinical trial outcomes (eg
-
Optimising peri-operative anaphylaxis management: end-tidal carbon dioxide monitoring and adrenaline titration: a reply Anaesthesia (IF 10.7) Pub Date : 2024-05-10 Amy Dodd, Paul J. Turner, Jasmeet Soar, Louise Savic
We thank Yang et al. [1] for their interest in our article [2] and for highlighting the difficulties of diagnosing peri-operative anaphylaxis in real time. The principal aim of this algorithm is to prevent respiratory or cardiovascular deterioration, cardiac arrest and death by promoting early effective treatment, which includes the early use of intravenous adrenaline irrespective of diagnostic uncertainty
-
Advanced life support interventions during intra-operative cardiac arrest among adults as reported to the 7th National Audit Project of the Royal College of Anaesthetists Anaesthesia (IF 10.7) Pub Date : 2024-05-10 Jerry P. Nolan, Richard A. Armstrong, Andrew D. Kane, Emira Kursumovic, Matthew T. Davies, Iain K. Moppett, Tim M. Cook, Jasmeet Soar
Few existing resuscitation guidelines include specific reference to intra-operative cardiac arrest, but its optimal treatment is likely to require some adaptation of standard protocols.
-
Patterns of opioid use after surgical discharge: a multicentre, prospective cohort study in 25 countries Anaesthesia (IF 10.7) Pub Date : 2024-05-09
Excessive opioid prescribing following surgery contributes to the growing opioid crisis. Prescribing practices are modifiable, yet data to guide appropriate prescription of opioids at surgical discharge remain sparse. This study aimed to evaluate factors associated with opioid consumption following discharge from surgery.
-
Surgical closure of the neck following thyroid surgery: an important area of anatomy for the anaesthetist Anaesthesia (IF 10.7) Pub Date : 2024-05-11 Karen Collins, Benjamin Stretch, Rajeev Advani
We have been involved in the emergency management of life-threatening thyroid haematomas and followed the multidisciplinary consensus guidelines published in Anaesthesia, resulting in safe management of these patients [1]. We had expected to expose the Skin; Cut sutures; Open skin; Open muscles; and Pack the wound (SCOOP). However, on more than one occasion, surgical closure of the neck wound with
-
-
Sarcopenia: it is time to attach more importance to this stealth killer in patients who are critically ill Anaesthesia (IF 10.7) Pub Date : 2024-05-08 Kunming Cheng, Cheng Li, Haiyang Wu
We read with great interest the recent article by Gustafson et al. [1]. The study evaluated the musculoskeletal health status of intensive care unit (ICU) survivors. Their findings suggested that, among 254 patients admitted to the ICU, 59% had musculoskeletal problems yet only 24% received physical therapy after discharge. Given the high incidence and risk of musculoskeletal disorders in patients
-
A pilot project to test the feasibility of automated text messaging to collect multi‐day patient‐reported outcomes related to pain interference after total joint arthroplasty in veterans Anaesthesia (IF 10.7) Pub Date : 2024-05-08 Allison H. Dorogi, Oluwatobi O. Hunter, Daniel M. Gessner, Jody C. Leng, Alex Kou, Edward R. Mariano
Acute postoperative pain trajectories may differ between surgical procedures [1] and individuals who undergo the same procedure [2]. To date, clinical measurement of acute pain has been generally limited to pain intensity, which provides an inadequate assessment of recovery [3]. Despite recommendations to incorporate patient-reported outcomes into peri-operative pain assessment and management [3],
-
Opioid analgesic exposure during the first trimester of pregnancy and the risk of major congenital malformations in infants: a systematic review and meta‐analysis† Anaesthesia (IF 10.7) Pub Date : 2024-05-08 Bianca Varney, Jonathan Brett, Helga Zoega, Malcolm B. Gillies, Madeline Powell, Brian T. Bateman, Antonia W. Shand, Sallie‐Anne Pearson, Alys Havard
SummaryBackgroundPrescribed opioid analgesics are frequently used to manage pain in pregnancy. However, the available literature regarding the teratogenic potential of opioid use during pregnancy has not been systematically summarised. This systematic review and meta‐analysis aimed to assess the quality of the evidence on these potential risks and calculate a pooled estimate of risk for any opioid
-
The relationship between traumatic exposure and pain perception in children: the moderating role of posttraumatic symptoms. Pain (IF 7.4) Pub Date : 2024-05-08 Einat Levy Gigi, Moriya Rachmani, Ruth Defrin
Adverse childhood experiences (ACEs) affect approximately half of all children worldwide. These experiences have been linked to increased pain sensitivity in adulthood and a higher likelihood of developing severe chronic pain. However, most studies have assessed the effects of ACEs retrospectively, long after they occurred, leaving room for other factors to influence the observed outcomes. We investigated
-
Probing white matter microstructure in youth with chronic pain and its relation to catastrophizing using neurite orientation dispersion and density imaging. Pain (IF 7.4) Pub Date : 2024-05-08 Inge Timmers, Emma E Biggs, Lisa Bruckert, Alexandra G Tremblay-McGaw, Hui Zhang, David Borsook, Laura E Simons
Chronic pain is common in young people and can have a major life impact. Despite the burden of chronic pain, mechanisms underlying chronic pain development and persistence are still poorly understood. Specifically, white matter (WM) connectivity has remained largely unexplored in pediatric chronic pain. Using diffusion-weighted imaging, this study examined WM microstructure in adolescents (age M =
-
Parental narrative style moderates the relation between pain-related attention and memory biases in youth with chronic pain. Pain (IF 7.4) Pub Date : 2024-05-08 Aline Wauters, Dimitri M L Van Ryckeghem, Melanie Noel, Kendra Mueri, Sabine Soltani, Tine Vervoort
Negatively biased pain memories robustly predict maladaptive pain outcomes in children. Both attention bias to pain and parental narrative style have been linked with the development of these negative biases, with previous studies indicating that how parents talk to their child about the pain might buffer the influence of children's attention bias to pain on the development of such negatively biased
-
Small fibre neuropathy frequently underlies the painful long-COVID syndrome. Pain (IF 7.4) Pub Date : 2024-05-07 Pietro Falco, Daniel Litewczuk, Giulia Di Stefano, Eleonora Galosi, Caterina Leone, Gianfranco De Stefano, Giuseppe Di Pietro, Lorenzo Tramontana, Maria Rosa Ciardi, Patrizia Pasculli, Maria Antonella Zingaropoli, Lars Arendt-Nielsen, Andrea Truini
Approximately 10% to 20% of individuals with previous SARS-CoV-2 infection may develop long-COVID syndrome, characterized by various physical and mental health issues, including pain. Previous studies suggested an association between small fibre neuropathy and pain in long-COVID cases. In this case-control study, our aim was to identify small fibre neuropathy in patients experiencing painful long-COVID
-
Statistical modeling of acute and chronic pain patient-reported outcomes obtained from ecological momentary assessment. Pain (IF 7.4) Pub Date : 2024-05-07 Andrew Leroux, Ciprian Crainiceanu, Scott Zeger, Margaret Taub, Briha Ansari, Tor D Wager, Emine Bayman, Christopher Coffey, Carl Langefeld, Robert McCarthy, Alex Tsodikov, Chad Brummet, Daniel J Clauw, Robert R Edwards, Martin A Lindquist
Ecological momentary assessment (EMA) allows for the collection of participant-reported outcomes (PROs), including pain, in the normal environment at high resolution and with reduced recall bias. Ecological momentary assessment is an important component in studies of pain, providing detailed information about the frequency, intensity, and degree of interference of individuals' pain. However, there
-
Pain reflects the informational value of nociceptive inputs. Pain (IF 7.4) Pub Date : 2024-05-07 Michel-Pierre Coll, Zoey Walden, Pierre-Alexandre Bourgoin, Veronique Taylor, Pierre Rainville, Manon Robert, Dang Khoa Nguyen, Pierre Jolicoeur, Mathieu Roy
Pain perception and its modulation are fundamental to human learning and adaptive behavior. This study investigated the hypothesis that pain perception is tied to pain's learning function. Thirty-one participants performed a threat conditioning task where certain cues were associated with a possibility of receiving a painful electric shock. The cues that signaled potential pain or safety were regularly
-
Longitudinal examination of associations with the onset of pediatric chronic pain at different pain locations. Pain (IF 7.4) Pub Date : 2024-05-07 Lisa-Marie Rau, Clarissa Humberg, Anna Könning, Nicola Rosenthal, Lorin Stahlschmidt, Julia Wager
Chronic pain is a frequent phenomenon in pediatrics. Little research explores whether there are factors that uniquely predict or accompany the onset of new chronic pain in different locations of the body. In this study, we report pediatric pain data for 3 location subsamples-headache, abdominal pain, and musculoskeletal pain-of a large secondary school sample (N = 2280). We distinguished between participants
-
Recent developments and challenges in positron emission tomography imaging of gliosis in chronic neuropathic pain. Pain (IF 7.4) Pub Date : 2024-05-07 Gaelle M Emvalomenos, James W M Kang, Bianca Jupp, Richelle Mychasiuk, Kevin A Keay, Luke A Henderson
Understanding the mechanisms that underpin the transition from acute to chronic pain is critical for the development of more effective and targeted treatments. There is growing interest in the contribution of glial cells to this process, with cross-sectional preclinical studies demonstrating specific changes in these cell types capturing targeted timepoints from the acute phase and the chronic phase
-
Hospital‐level flow measurement to detect nitrous oxide leakage Anaesthesia (IF 10.7) Pub Date : 2024-05-03 Justin J. Skowno, H. Reza Kahlaee, Andrew J. Inglis, Darren McKinnon, Kathryn Asher
Nitrous oxide has a significant carbon footprint, and global initiatives are in progress to diminish its environmental impact in agriculture, industry and healthcare [1]. It is piped to locations in many healthcare environments, and in some hospitals, these systems can leak most of the gas they carry (75–95%) [1]. Leak detection traditionally relies on static pressure testing, a time-consuming and
-
The science of climate change and the effect of anaesthetic gas emissions: a reply Anaesthesia (IF 10.7) Pub Date : 2024-05-03 Christopher Prabhakar, Rakesh V. Sondekoppam, Vivian H. Y. Ip
Physicians are not climate scientists and are not trained in the intricacies of how greenhouse gases affect climate change. Hence it is refreshing to read the thought-provoking review article by Slingo and Slingo on the impact of volatile anaesthetic gas emissions on climate change [1]. They have suggested that only desflurane will have full radiative effect on global warming due to its longer atmospheric
-
Airway management in patients with suspected or confirmed cervical spine injury Anaesthesia (IF 10.7) Pub Date : 2024-05-03 Matthew D. Wiles, Helen A. Iliff, Katherine Brooks, Egidio J. Da Silva, Mike Donnellon, Adrian Gardner, Matthew Harris, Caroline Leech, Steve Mathieu, Paul Moor, Lara Prisco, Kate Rivett, Frances Tait, Kariem El‐Boghdadly
SummaryBackgroundThere are concerns that airway management in patients with suspected or confirmed cervical spine injury may exacerbate an existing neurological deficit, cause a new spinal cord injury or be hazardous due to precautions to avoid neurological injury. However, there are no evidence‐based guidelines for practicing clinicians to support safe and effective airway management in this setting
-
Methods for pragmatic randomized clinical trials of pain therapies: IMMPACT statement. Pain (IF 7.4) Pub Date : 2024-05-03 David Hohenschurz-Schmidt, Dan Cherkin, Andrew S C Rice, Robert H Dworkin, Dennis C Turk, Michael P McDermott, Matthew J Bair, Lynn L DeBar, Robert R Edwards, Scott R Evans, John T Farrar, Robert D Kerns, Michael C Rowbotham, Ajay D Wasan, Penney Cowan, McKenzie Ferguson, Roy Freeman, Jennifer S Gewandter, Ian Gilron, Hanna Grol-Prokopczyk, Smriti Iyengar, Cornelia Kamp, Barbara I Karp, Bethea A Kleykamp
Pragmatic, randomized, controlled trials hold the potential to directly inform clinical decision making and health policy regarding the treatment of people experiencing pain. Pragmatic trials are designed to replicate or are embedded within routine clinical care and are increasingly valued to bridge the gap between trial research and clinical practice, especially in multidimensional conditions, such
-
Translation of paclitaxel-induced peripheral neurotoxicity from mice to patients: the importance of model selection. Pain (IF 7.4) Pub Date : 2024-05-02 Guido Cavaletti, Paola Alberti, Annalisa Canta, Valentina Carozzi, Laura Cherchi, Alessia Chiorazzi, Luca Crippa, Paola Marmiroli, Cristina Meregalli, Eleonora Pozzi, Virginia Rodriguez-Menendez, Christian Steinkühler, Simonetta Andrea Licandro
Paclitaxel-induced peripheral neurotoxicity (PIPN) is a potentially dose-limiting side effect in anticancer chemotherapy. Several animal models of PIPN exist, but their results are sometimes difficult to be translated into the clinical setting. We compared 2 widely used PIPN models characterized by marked differences in their methodologies. Female C57BL/6JOlaHsd mice were used, and they received only
-
Patients' perspective on the chronic pain classification in the 11th revision of the International Classification of Diseases (ICD-11): results from an international web-based survey. Pain (IF 7.4) Pub Date : 2024-05-02 Beatrice Korwisi, Ginea Hay, Patrice Forget, Deirdre Ryan, Rolf-Detlef Treede, Winfried Rief, Antonia Barke
The 11th revision of the International Classification of Diseases and Related Health Problems (ICD-11) aims at improving the lives of persons with the lived experience of chronic pain by providing clearly defined and clinically useful diagnoses that can reduce stigma, facilitate communication, and improve access to pain management, among others. The aim of this study was to assess the perspective of
-
Terpenes from Cannabis sativa induce antinociception in a mouse model of chronic neuropathic pain via activation of adenosine A2A receptors. Pain (IF 7.4) Pub Date : 2024-05-02 Abigail M Schwarz, Attila Keresztes, Thai Bui, Ryan Hecksel, Adrian Peña, Brianna Lent, Zhan-Guo Gao, Martín Gamez-Rivera, Caleb A Seekins, Kerry Chou, Taylor L Appel, Kenneth A Jacobson, Fahad A Al-Obeidi, John M Streicher
Terpenes are small hydrocarbon compounds that impart aroma and taste to many plants, including Cannabis sativa. A number of studies have shown that terpenes can produce pain relief in various pain states in both humans and animals. However, these studies were methodologically limited and few established mechanisms of action. In our previous work, we showed that the terpenes geraniol, linalool, β-pinene
-
The downside to choice: instrumental control increases conditioned nocebo hyperalgesia. Pain (IF 7.4) Pub Date : 2024-05-02 Biya Tang, Evan Livesey, Ben Colagiuri
Nocebo hyperalgesia is a pervasive problem in which the treatment context triggers negative expectations that exacerbate pain. Thus, developing ethical strategies to mitigate nocebo hyperalgesia is crucial. Emerging research suggests that choice has the capacity to reduce nocebo side effects, but choice effects on nocebo hyperalgesia have not been explored. This study investigated the impact of choice
-
The associations of opioid and benzodiazepine prescriptions with injuries among US military service members. Pain (IF 7.4) Pub Date : 2024-05-02 Marija S Kelber, Derek J Smolenski, Bradley E Belsher, Kevin O'Gallagher, Fuad Issa, Lindsay Thonsen Stewart, Daniel P Evatt
Given the high rates of physical trauma and pain among service members, opioid-prescribing practices and use patterns have significant implications for the well-being of service members and can affect military medicine and personnel readiness. This study measured the association between prescribed opioid and benzodiazepine medications and subsequently reported injuries (accidental, alcohol and drug
-
Improved outcome with individualised antifibrinolytic therapy: what is the evidence? Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-30 Daniel Bolliger, Marco Ranucci
-
Analgesic candidate adenosine A3 receptors are expressed by perineuronal peripheral macrophages in human dorsal root ganglion and spinal cord microglia. Pain (IF 7.4) Pub Date : 2024-04-30 Matthew R Sapio, Ellen S Staedtler, Diana M King, Dragan Maric, Jahandar Jahanipour, Andre Ghetti, Kenneth A Jacobson, Andrew J Mannes, Michael J Iadarola
Adenosine receptors are a family of purinergic G protein-coupled receptors that are widely distributed in bodily organs and in the peripheral and central nervous systems. Recently, antihyperalgesic actions have been suggested for the adenosine A3 receptor, and its agonists have been proposed as new neuropathic pain treatments. We hypothesized that these receptors may be expressed in nociceptive primary
-
Post‐intensive care syndrome: survival, but at what cost? Anaesthesia (IF 10.7) Pub Date : 2024-04-29 Caroline Sampson
-
Incidence and impact of cardiovascular complications after major abdominal surgery Anaesthesia (IF 10.7) Pub Date : 2024-04-29 Rui‐Peng Zhong, Bing‐Cheng Zhao, Gui‐Ming Huang
The international, prospective cohort study (CArdiovaSCulAr outcomes after major abDominal surgEry, CASCADE) reported that postoperative cardiovascular complications, as defined by the Standardised Endpoints for Perioperative Medicine-Core Outcome Measures for Perioperative and Anaesthetic Care (StEP-COMPAC), occurred infrequently in patients undergoing major abdominal surgery (incidence 2.5%), but
-
Perioperative anaphylaxis and the principle of primum non nocere Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-26 Karen Pedersen, Sarah Green
-
Point-of-care testing for tranexamic acid efficacy: a proof-of-concept study in cardiac surgical patients Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-26 Ryogo Yoshii, Yuya Takahashi, Kenichi A. Tanaka, Hidetake Kawajiri, Teiji Sawa, Fumimasa Amaya, Satoru Ogawa
Low-dose tranexamic acid (TXA) has been recently recommended for cardiopulmonary bypass (CPB) to reduce associated complications. Although point-of-care laboratory tests for TXA concentrations are unavailable, a novel TPA-test on the ClotPro® system can measure TXA-induced inhibition of fibrinolysis. We evaluated the performance of the TPA-test and in patients undergoing surgery requiring CPB. Blood
-
Postoperative myocardial injury phenotypes and self-reported disability in patients undergoing noncardiac surgery. Comment on Br J Anaesth 2024; 132: 35–44 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-25 Hui-Zen Hee, Cheng-Wei Lu
-
Performance of ChatGPT on a free-response anaesthesia primary examination Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-25 Steven C. Cai, Alpha M.S. Tung, Adam T. Eslick
-
Intraoperative hypotension and postoperative outcomes. Response to Br J Anaesth 2024; 132:616–618 Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-25 Filippo D'Amico, Alessandro Pruna, Giovanni Landoni
-
It's not easy being green: the continued lack of sustainable anaesthetic options Anaesthesia (IF 10.7) Pub Date : 2024-04-23 Kaitlyn Kulesus, Casey Windrix, Huy Nhan
We congratulate Bernat et al. on their retrospective observational study that highlights the high carbon footprint of anaesthesia [1]. They hypothesised that the predominance of total intravenous anaesthesia (TIVA) would reduce the carbon footprint in affiliated French hospitals. The study demonstrates the need for standardised techniques to facilitate accurate measurement of anaesthetic greenhouse
-
Comparing performance of the McGrath™ videolaryngoscope with direct laryngoscopy for rapid sequence intubation Anaesthesia (IF 10.7) Pub Date : 2024-04-23 Fu‐Shan Xue, Dan‐Feng Wang, Xiao‐Chun Zheng
In the recent study by Kriege et al. [1], comparing performance of the McGrath™ videolaryngoscope with direct laryngoscopy for rapid sequence intubation in the operating theatre, 94 of 500 patients (19%) in the direct laryngoscopy group had a Cormack and Lehane grade view ≥ 3.; however, study participants had an expected normal airway, direct laryngoscopy was performed under sufficient neuromuscular
-
The science of climate change and the effect of anaesthetic gas emissions. Useful metrics for ethical decision making Anaesthesia (IF 10.7) Pub Date : 2024-04-23 Alain Kalmar, An Teunkens, Steffen Rex
We support the call by Slingo and Slingo for anaesthetists to adopt a sustainability framework informed by climate science, which urgently stresses the need to reduce our climate impact [1]. As rightly emphasised, the global warming potential (GWP) metric has faced criticism for overestimating the climate impact of short-lived climate pollutants and potentially leading opportunistic policymakers to
-
Medication errors contributing to obstetric cardiac arrest in NAP7 Anaesthesia (IF 10.7) Pub Date : 2024-04-23 Noha Tageldin, Kailash Bhatia
It is reassuring to see that obstetric patients are four times less likely to experience a cardiac arrest than patients having non-obstetric surgery [1]. Further, no cardiac arrests were attributed to failed tracheal intubation, aspiration, local anaesthetic systemic toxicity or remifentanil patient-controlled analgesia, suggesting significant safety improvements in these areas. Anaesthesia-related
-
The rostral ventromedial medulla modulates pain and depression-related behaviors caused by social stress. Pain (IF 7.4) Pub Date : 2024-04-23 Marco Pagliusi, Anna P Amorim-Marques, Mary Kay Lobo, Francisco S Guimarães, Sabrina F Lisboa, Felipe V Gomes
The rostral ventromedial medulla (RVM) is a crucial structure in the descending pain modulatory system, playing a key role as a relay for both the facilitation and inhibition of pain. The chronic social defeat stress (CSDS) model has been widely used to study stress-induced behavioral impairments associated with depression in rodents. Several studies suggest that CSDS also causes changes related to
-
Association between EEG metrics and continuous cerebrovascular autoregulation assessment: a scoping review Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-20 Stefan Y. Bögli, Marina S. Cherchi, Erta Beqiri, Peter Smielewski
Cerebrovascular autoregulation is defined as the capacity of cerebral blood vessels to maintain stable cerebral blood flow despite changing blood pressure. It is assessed using the pressure reactivity index (the correlation coefficient between mean arterial blood pressure and intracranial pressure). The objective of this scoping review is to describe the existing evidence concerning the association
-
Utilising intraoperative respiratory dynamic features for developing and validating an explainable machine learning model for postoperative pulmonary complications Br. J. Anaesth. (IF 9.8) Pub Date : 2024-04-18 Peiyi Li, Shuanliang Gao, Yaqiang Wang, RuiHao Zhou, Guo Chen, Weimin Li, Xuechao Hao, Tao Zhu
Timely detection of modifiable risk factors for postoperative pulmonary complications (PPCs) could inform ventilation strategies that attenuate lung injury. We sought to develop, validate, and internally test machine learning models that use intraoperative respiratory features to predict PPCs. We analysed perioperative data from a cohort comprising patients aged 65 yr and older at an academic medical
-
Still a ‘boys’ club': a qualitative analysis of how gender affects a career in anaesthesia in Australia and Aotearoa New Zealand Anaesthesia (IF 10.7) Pub Date : 2024-04-17 J. C. Carter, N. Purcell, C. H. Stewart, G. C. Pearce, M. Balkin, K. J. Allen
Gender inequity remains an issue in anaesthesia despite increasing numbers of women training and achieving fellowship in the speciality. Women are under-represented in all areas of anaesthetic research, academia and leadership. The Gender Equity Subcommittee of the Australian and New Zealand College of Anaesthetists recently conducted a survey asking “Does gender still matter in the pursuit of a career
-
Self-Citation Patterns of Anesthesiology Journals Indexed in the Journal Citation Reports Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Burhan Dost, Alessandro De Cassai
An abstract is unavailable.
-
Letter Regarding the Potential Improper Use of the Individual Typology Angle in the Context of Disparate Bias in Pulse Oximetry Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Wim Verkruysse, Michael B. Jaffe
An abstract is unavailable.
-
Physicochemical Stability of Ketamine After Reconstitution for Injection: A Scoping Review Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Mohammed Adinoyi Usman, Orshio Uga Donald, Dalhat Salahu, Irene Irenosen Akhideno
An abstract is unavailable.
-
In Response Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Alexis L. Cull, Mercede N. Erickson
An abstract is unavailable.
-
Neostigmine and Postoperative Cognitive Dysfunction in the Elderly: Teaching an Old Dog a New Trick? Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Hisako Okada, Amir L. Butt, Pamela R. Roberts, Kenichi A. Tanaka
An abstract is unavailable.
-
In Response Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Emil Peska, Mrinalini Balki, Wesla Pfeifer, Cynthia Maxwell, Xiang Y. Ye, Kristi Downey, Jose C. A. Carvalho
An abstract is unavailable.
-
Caveats for Interpreting the Results of Up-and-Down Dose-Finding Studies for Prophylactic Oxytocin at Cesarean Delivery Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 James H. Bamber, Dominique N. Lucas
An abstract is unavailable.
-
Bibliometric Analysis of Contributions of Anesthesiology Journals and Anesthesiologists to Operating Room Management Science Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Franklin Dexter, Sara Scheib, Wei Xie, Richard H. Epstein
based on 2 of the authors’ curation of an online, comprehensive bibliography of OR management articles and corresponding referenced course materials. METHODS: We studied all 2938 publications having Scopus’ SciVal topic T.6319 (OR management) more than 28 years from 1996 through May 2023, including 8608 distinct authors. RESULTS: Half (50%) of the publications were absent from PubMed, and the percentage
-
Maternal Morbidity According to Mode of Delivery Among Pregnant Patients With Pulmonary Hypertension Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Marie-Louise Meng, Matthew Fuller, Jerome J. Federspiel, Matthew Engelhard, Ashley McNeil, Liliane Ernst, Ashraf S. Habib, Svati H. Shah, Johanna Quist-Nelson, Karthik Raghunathan, Tetsu Ohnuma, Vijay Krishnamoorthy
livery mode with severe maternal morbidity events during delivery hospitalization among patients with pulmonary hypertension. METHODS: This retrospective cohort study used the Premier inpatient administrative database. Patients delivering ≥25 weeks gestation from January 1, 2016, to September 30, 2020, and with pulmonary hypertension were included. The primary analysis compared intended vaginal delivery
-
Postpartum Opioid Prescribing and Persistent Use in Western Countries Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Jashvant Poeran, Chang H. Park
An abstract is unavailable.
-
Pro-Con Debate: Universal Versus Selective Continuous Monitoring of Postoperative Patients Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 George T. Blike, Susan P. McGrath, Michelle A. Ochs Kinney, Bhargavi Gali
hesia care unit until discharge from the hospital. The strongest arguments for universal monitoring relate to inadequate assessment and algorithms for patient risk. We argue that the need for hospitalization in and of itself is a sufficient predictor of an individual’s risk for unexpected respiratory deterioration. In addition, general care units carry the added risk that even the most severe respiratory
-
Enhanced Postoperative Monitoring: Mixed Realities and New Frontiers Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Satya Krishna Ramachandran
An abstract is unavailable.
-
Artificial Intelligence: Perceptions and Attitudes Anesth. Analg. (IF 5.7) Pub Date : 2024-04-15 Naveen Nathan
An abstract is unavailable.