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An in-depth evaluation of federated learning on biomedical natural language processing for information extraction npj Digit. Med. (IF 15.2) Pub Date : 2024-05-15 Le Peng, Gaoxiang Luo, Sicheng Zhou, Jiandong Chen, Ziyue Xu, Ju Sun, Rui Zhang
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A systematic review and meta-analysis of artificial intelligence versus clinicians for skin cancer diagnosis npj Digit. Med. (IF 15.2) Pub Date : 2024-05-14 Maria Paz Salinas, Javiera Sepúlveda, Leonel Hidalgo, Dominga Peirano, Macarena Morel, Pablo Uribe, Veronica Rotemberg, Juan Briones, Domingo Mery, Cristian Navarrete-Dechent
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Shortcut learning in medical AI hinders generalization: method for estimating AI model generalization without external data npj Digit. Med. (IF 15.2) Pub Date : 2024-05-14 Cathy Ong Ly, Balagopal Unnikrishnan, Tony Tadic, Tirth Patel, Joe Duhamel, Sonja Kandel, Yasbanoo Moayedi, Michael Brudno, Andrew Hope, Heather Ross, Chris McIntosh
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FDA-cleared home sleep apnea testing devices npj Digit. Med. (IF 15.2) Pub Date : 2024-05-13 Ji Hyeun Park, Changwon Wang, Hangsik Shin
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Generalized sleep decoding with basal ganglia signals in multiple movement disorders npj Digit. Med. (IF 15.2) Pub Date : 2024-05-10 Zixiao Yin, Huiling Yu, Tianshuo Yuan, Clay Smyth, Md Fahim Anjum, Guanyu Zhu, Ruoyu Ma, Yichen Xu, Qi An, Yifei Gan, Timon Merk, Guofan Qin, Hutao Xie, Ning Zhang, Chunxue Wang, Yin Jiang, Fangang Meng, Anchao Yang, Wolf-Julian Neumann, Philip Starr, Simon Little, Luming Li, Jianguo Zhang
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The application of machine learning techniques in posttraumatic stress disorder: a systematic review and meta-analysis npj Digit. Med. (IF 15.2) Pub Date : 2024-05-09 Jing Wang, Hui Ouyang, Runda Jiao, Suhui Cheng, Haiyan Zhang, Zhilei Shang, Yanpu Jia, Wenjie Yan, Lili Wu, Weizhi Liu
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Distribution shift detection for the postmarket surveillance of medical AI algorithms: a retrospective simulation study npj Digit. Med. (IF 15.2) Pub Date : 2024-05-09 Lisa M. Koch, Christian F. Baumgartner, Philipp Berens
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Charting a new course in healthcare: early-stage AI algorithm registration to enhance trust and transparency npj Digit. Med. (IF 15.2) Pub Date : 2024-05-08 Michel E. van Genderen, Davy van de Sande, Lotty Hooft, Andreas Alois Reis, Alexander D. Cornet, Jacobien H. F. Oosterhoff, Björn J. P. van der Ster, Joost Huiskens, Reggie Townsend, Jasper van Bommel, Diederik Gommers, Jeroen van den Hoven
AI holds the potential to transform healthcare, promising improvements in patient care. Yet, realizing this potential is hampered by over-reliance on limited datasets and a lack of transparency in validation processes. To overcome these obstacles, we advocate the creation of a detailed registry for AI algorithms. This registry would document the development, training, and validation of AI models, ensuring
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Online cognitive monitoring technology for people with Parkinson’s disease and REM sleep behavioural disorder npj Digit. Med. (IF 15.2) Pub Date : 2024-05-07 Maria Bălăeţ, Falah Alhajraf, Tanja Zerenner, Jessica Welch, Jamil Razzaque, Christine Lo, Valentina Giunchiglia, William Trender, Annalaura Lerede, Peter J. Hellyer, Sanjay G. Manohar, Paresh Malhotra, Michele Hu, Adam Hampshire
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Multimodal data fusion using sparse canonical correlation analysis and cooperative learning: a COVID-19 cohort study npj Digit. Med. (IF 15.2) Pub Date : 2024-05-07 Ahmet Gorkem Er, Daisy Yi Ding, Berrin Er, Mertcan Uzun, Mehmet Cakmak, Christoph Sadee, Gamze Durhan, Mustafa Nasuh Ozmen, Mine Durusu Tanriover, Arzu Topeli, Yesim Aydin Son, Robert Tibshirani, Serhat Unal, Olivier Gevaert
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Exploring cognitive reserve’s influence: unveiling the dynamics of digital telerehabilitation in Parkinson’s Disease Resilience npj Digit. Med. (IF 15.2) Pub Date : 2024-05-06 Sara Isernia, Sonia Di Tella, Federica Rossetto, Francesca Borgnis, Olivia Realdon, Monia Cabinio, Chiara Pagliari, Alessandro Torchio, Anna Castagna, Valeria Blasi, Maria Caterina Silveri, Francesca Baglio
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Optical coherence tomography choroidal enhancement using generative deep learning npj Digit. Med. (IF 15.2) Pub Date : 2024-05-04 Valentina Bellemo, Ankit Kumar Das, Syna Sreng, Jacqueline Chua, Damon Wong, Janika Shah, Rahul Jonas, Bingyao Tan, Xinyu Liu, Xinxing Xu, Gavin Siew Wei Tan, Rupesh Agrawal, Daniel Shu Wei Ting, Liu Yong, Leopold Schmetterer
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Sync fast and solve things—best practices for responsible digital health npj Digit. Med. (IF 15.2) Pub Date : 2024-05-04 Constantin Landers, Alessandro Blasimme, Effy Vayena
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Artificial intelligence in digital pathology: a systematic review and meta-analysis of diagnostic test accuracy npj Digit. Med. (IF 15.2) Pub Date : 2024-05-04 Clare McGenity, Emily L. Clarke, Charlotte Jennings, Gillian Matthews, Caroline Cartlidge, Henschel Freduah-Agyemang, Deborah D. Stocken, Darren Treanor
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A physiologically-based digital twin for alcohol consumption—predicting real-life drinking responses and long-term plasma PEth npj Digit. Med. (IF 15.2) Pub Date : 2024-05-03 Henrik Podéus, Christian Simonsson, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Peter Lundberg, William Lövfors, Gunnar Cedersund
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FFA-GPT: an automated pipeline for fundus fluorescein angiography interpretation and question-answer npj Digit. Med. (IF 15.2) Pub Date : 2024-05-03 Xiaolan Chen, Weiyi Zhang, Pusheng Xu, Ziwei Zhao, Yingfeng Zheng, Danli Shi, Mingguang He
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Constructing personalized characterizations of structural brain aberrations in patients with dementia using explainable artificial intelligence npj Digit. Med. (IF 15.2) Pub Date : 2024-05-02 Esten H. Leonardsen, Karin Persson, Edvard Grødem, Nicola Dinsdale, Till Schellhorn, James M. Roe, Didac Vidal-Piñeiro, Øystein Sørensen, Tobias Kaufmann, Eric Westman, Andre Marquand, Geir Selbæk, Ole A. Andreassen, Thomas Wolfers, Lars T. Westlye, Yunpeng Wang
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Robust language-based mental health assessments in time and space through social media npj Digit. Med. (IF 15.2) Pub Date : 2024-05-02 Siddharth Mangalik, Johannes C. Eichstaedt, Salvatore Giorgi, Jihu Mun, Farhan Ahmed, Gilvir Gill, Adithya V. Ganesan, Shashanka Subrahmanya, Nikita Soni, Sean A. P. Clouston, H. Andrew Schwartz
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A critical assessment of using ChatGPT for extracting structured data from clinical notes npj Digit. Med. (IF 15.2) Pub Date : 2024-05-01 Jingwei Huang, Donghan M. Yang, Ruichen Rong, Kuroush Nezafati, Colin Treager, Zhikai Chi, Shidan Wang, Xian Cheng, Yujia Guo, Laura J. Klesse, Guanghua Xiao, Eric D. Peterson, Xiaowei Zhan, Yang Xie
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Video clips for patient comprehension of atrial fibrillation and deep vein thrombosis in emergency care. A randomised clinical trial npj Digit. Med. (IF 15.2) Pub Date : 2024-04-30 Santi Di Pietro, Ilaria Ferrari, Giuseppe Bulgari, Maria Lorenza Muiesan, Francesco Falaschi, Annalisa De Silvestri, Luigia Scudeller, Valeria Musella, Simone Saglio, Beatrice Re, Elena Mattiuzzo, Fabio Cherubini, Stefano Perlini
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RETFound-enhanced community-based fundus disease screening: real-world evidence and decision curve analysis npj Digit. Med. (IF 15.2) Pub Date : 2024-04-30 Juzhao Zhang, Senlin Lin, Tianhao Cheng, Yi Xu, Lina Lu, Jiangnan He, Tao Yu, Yajun Peng, Yuejie Zhang, Haidong Zou, Yingyan Ma
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Evidence-based health messages increase intention to cope with loneliness in Germany: a randomized controlled online trial npj Digit. Med. (IF 15.2) Pub Date : 2024-04-29 Shuyan Liu, Matthias Haucke, Luisa Wegner, Jennifer Gates, Till Bärnighausen, Maya Adam
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Effectiveness of DialBetesPlus, a self-management support system for diabetic kidney disease: Randomized controlled trial npj Digit. Med. (IF 15.2) Pub Date : 2024-04-27 Kayo Waki, Mitsuhiko Nara, Syunpei Enomoto, Makiko Mieno, Eiichiro Kanda, Akiko Sankoda, Yuki Kawai, Kana Miyake, Hiromichi Wakui, Yuya Tsurutani, Nobuhito Hirawa, Tadashi Yamakawa, Shiro Komiya, Akihiro Isogawa, Shinobu Satoh, Taichi Minami, Tamio Iwamoto, Tatsuro Takano, Yasuo Terauchi, Kouichi Tamura, Toshimasa Yamauchi, Masaomi Nangaku, Naoki Kashihara, Kazuhiko Ohe
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Levels of autonomy in FDA-cleared surgical robots: a systematic review npj Digit. Med. (IF 15.2) Pub Date : 2024-04-26 Audrey Lee, Turner S. Baker, Joshua B. Bederson, Benjamin I. Rapoport
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Optimization of hepatological clinical guidelines interpretation by large language models: a retrieval augmented generation-based framework npj Digit. Med. (IF 15.2) Pub Date : 2024-04-23 Simone Kresevic, Mauro Giuffrè, Milos Ajcevic, Agostino Accardo, Lory S. Crocè, Dennis L. Shung
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The dichotomy of diagnostics: exploring the value for consumers, clinicians and care pathways npj Digit. Med. (IF 15.2) Pub Date : 2024-04-23 Dylan Powell, Aiden Hannah
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Augmented non-hallucinating large language models as medical information curators npj Digit. Med. (IF 15.2) Pub Date : 2024-04-23 Stephen Gilbert, Jakob Nikolas Kather, Aidan Hogan
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Real-time near infrared artificial intelligence using scalable non-expert crowdsourcing in colorectal surgery npj Digit. Med. (IF 15.2) Pub Date : 2024-04-22 Garrett Skinner, Tina Chen, Gabriel Jentis, Yao Liu, Christopher McCulloh, Alan Harzman, Emily Huang, Matthew Kalady, Peter Kim
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Predicting non-muscle invasive bladder cancer outcomes using artificial intelligence: a systematic review using APPRAISE-AI npj Digit. Med. (IF 15.2) Pub Date : 2024-04-18 Jethro C. C. Kwong, Jeremy Wu, Shamir Malik, Adree Khondker, Naveen Gupta, Nicole Bodnariuc, Krishnateja Narayana, Mikail Malik, Theodorus H. van der Kwast, Alistair E. W. Johnson, Alexandre R. Zlotta, Girish S. Kulkarni
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Visual interpretable MRI fine grading of meniscus injury for intelligent assisted diagnosis and treatment npj Digit. Med. (IF 15.2) Pub Date : 2024-04-15 Anlin Luo, Shuiping Gou, Nuo Tong, Bo Liu, Licheng Jiao, Hu Xu, Yingchun Wang, Tan Ding
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Deep learning evaluation of echocardiograms to identify occult atrial fibrillation npj Digit. Med. (IF 15.2) Pub Date : 2024-04-13 Neal Yuan, Nathan R. Stein, Grant Duffy, Roopinder K. Sandhu, Sumeet S. Chugh, Peng-Sheng Chen, Carine Rosenberg, Christine M. Albert, Susan Cheng, Robert J. Siegel, David Ouyang
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Towards a common European ethical and legal framework for conducting clinical research: the GATEKEEPER experience npj Digit. Med. (IF 15.2) Pub Date : 2024-04-13 Alessia Maccaro, Vasiliki Tsiompanidou, Davide Piaggio, Alba M. Gallego Montejo, Gloria Cea Sánchez, Jordi de Batlle, Adrian Quesada Rodriguez, Giuseppe Fico, Leandro Pecchia
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Navigating the U.S. regulatory landscape for neurologic digital health technologies npj Digit. Med. (IF 15.2) Pub Date : 2024-04-12 Neil A. Busis, Dilshad Marolia, Robert Montgomery, Laura J. Balcer, Steven L. Galetta, Scott N. Grossman
Digital health technologies (DHTs) can transform neurological assessments, improving quality and continuity of care. In the United States, the Food & Drug Administration (FDA) oversees the safety and efficacy of these technologies, employing a detailed regulatory process that classifies devices based on risk and requires rigorous review and post-market surveillance. Following FDA approval, DHTs enter
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Self-supervised learning for human activity recognition using 700,000 person-days of wearable data npj Digit. Med. (IF 15.2) Pub Date : 2024-04-12 Hang Yuan, Shing Chan, Andrew P. Creagh, Catherine Tong, Aidan Acquah, David A. Clifton, Aiden Doherty
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International perspectives on measuring national digital public health system maturity through a multidisciplinary Delphi study npj Digit. Med. (IF 15.2) Pub Date : 2024-04-12 Laura Maaß, Hajo Zeeb, Heinz Rothgang
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Whole-heart electromechanical simulations using Latent Neural Ordinary Differential Equations npj Digit. Med. (IF 15.2) Pub Date : 2024-04-11 Matteo Salvador, Marina Strocchi, Francesco Regazzoni, Christoph M. Augustin, Luca Dede’, Steven A. Niederer, Alfio Quarteroni
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Understanding the errors made by artificial intelligence algorithms in histopathology in terms of patient impact npj Digit. Med. (IF 15.2) Pub Date : 2024-04-10 Harriet Evans, David Snead
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The potential for artificial intelligence to transform healthcare: perspectives from international health leaders npj Digit. Med. (IF 15.2) Pub Date : 2024-04-09 Christina Silcox, Eyal Zimlichmann, Katie Huber, Neil Rowen, Robert Saunders, Mark McClellan, Charles N. Kahn, Claudia A. Salzberg, David W. Bates
Artificial intelligence (AI) has the potential to transform care delivery by improving health outcomes, patient safety, and the affordability and accessibility of high-quality care. AI will be critical to building an infrastructure capable of caring for an increasingly aging population, utilizing an ever-increasing knowledge of disease and options for precision treatments, and combatting workforce
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Human-AI interaction in skin cancer diagnosis: a systematic review and meta-analysis npj Digit. Med. (IF 15.2) Pub Date : 2024-04-09 Isabelle Krakowski, Jiyeong Kim, Zhuo Ran Cai, Roxana Daneshjou, Jan Lapins, Hanna Eriksson, Anastasia Lykou, Eleni Linos
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The algorithm journey map: a tangible approach to implementing AI solutions in healthcare npj Digit. Med. (IF 15.2) Pub Date : 2024-04-09 William Boag, Alifia Hasan, Jee Young Kim, Mike Revoir, Marshall Nichols, William Ratliff, Michael Gao, Shira Zilberstein, Zainab Samad, Zahra Hoodbhoy, Mushyada Ali, Nida Saddaf Khan, Manesh Patel, Suresh Balu, Mark Sendak
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Challenges and opportunities of deep learning for wearable-based objective sleep assessment npj Digit. Med. (IF 15.2) Pub Date : 2024-04-04 Bing Zhai, Greg J. Elder, Alan Godfrey
In recent years the intersection of wearable technologies and machine learning (ML) based deep learning (DL) approaches have highlighted their potential in sleep research. Yet, a recent study published in NPJ Digital Medicine highlights the generalization limitations of DL models in sleep-wake classification using actigraphy data. Here, this article discusses some of the challenges and opportunities
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Evaluating large language models as agents in the clinic npj Digit. Med. (IF 15.2) Pub Date : 2024-04-03 Nikita Mehandru, Brenda Y. Miao, Eduardo Rodriguez Almaraz, Madhumita Sushil, Atul J. Butte, Ahmed Alaa
Recent developments in large language models (LLMs) have unlocked opportunities for healthcare, from information synthesis to clinical decision support. These LLMs are not just capable of modeling language, but can also act as intelligent “agents” that interact with stakeholders in open-ended conversations and even influence clinical decision-making. Rather than relying on benchmarks that measure a
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Contemporary attitudes and beliefs on coronary artery calcium from social media using artificial intelligence npj Digit. Med. (IF 15.2) Pub Date : 2024-03-30 Sulaiman Somani, Sujana Balla, Allison W. Peng, Ramzi Dudum, Sneha Jain, Khurram Nasir, David J. Maron, Tina Hernandez-Boussard, Fatima Rodriguez
Coronary artery calcium (CAC) is a powerful tool to refine atherosclerotic cardiovascular disease (ASCVD) risk assessment. Despite its growing interest, contemporary public attitudes around CAC are not well-described in literature and have important implications for shared decision-making around cardiovascular prevention. We used an artificial intelligence (AI) pipeline consisting of a semi-supervised
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Foundation metrics for evaluating effectiveness of healthcare conversations powered by generative AI npj Digit. Med. (IF 15.2) Pub Date : 2024-03-29 Mahyar Abbasian, Elahe Khatibi, Iman Azimi, David Oniani, Zahra Shakeri Hossein Abad, Alexander Thieme, Ram Sriram, Zhongqi Yang, Yanshan Wang, Bryant Lin, Olivier Gevaert, Li-Jia Li, Ramesh Jain, Amir M. Rahmani
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The clinician-AI interface: intended use and explainability in FDA-cleared AI devices for medical image interpretation npj Digit. Med. (IF 15.2) Pub Date : 2024-03-26 Stephanie L. McNamara, Paul H. Yi, William Lotter
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Anti- and pro-fibrillatory effects of pulmonary vein isolation gaps in human atrial fibrillation digital twins npj Digit. Med. (IF 15.2) Pub Date : 2024-03-26 Ze Jin, Taehyun Hwang, Daehoon Kim, Byounghyun Lim, Oh-Seok Kwon, Sangbin Kim, Moon-Hyun Kim, Je-Wook Park, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
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A remote digital memory composite to detect cognitive impairment in memory clinic samples in unsupervised settings using mobile devices npj Digit. Med. (IF 15.2) Pub Date : 2024-03-26 David Berron, Wenzel Glanz, Lindsay Clark, Kristin Basche, Xenia Grande, Jeremie Güsten, Ornella V. Billette, Ina Hempen, Muhammad Hashim Naveed, Nadine Diersch, Michaela Butryn, Annika Spottke, Katharina Buerger, Robert Perneczky, Anja Schneider, Stefan Teipel, Jens Wiltfang, Sterling Johnson, Michael Wagner, Frank Jessen, Emrah Düzel
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Digital twins for health: a scoping review npj Digit. Med. (IF 15.2) Pub Date : 2024-03-22 Evangelia Katsoulakis, Qi Wang, Huanmei Wu, Leili Shahriyari, Richard Fletcher, Jinwei Liu, Luke Achenie, Hongfang Liu, Pamela Jackson, Ying Xiao, Tanveer Syeda-Mahmood, Richard Tuli, Jun Deng
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Mimicking clinical trials with synthetic acute myeloid leukemia patients using generative artificial intelligence npj Digit. Med. (IF 15.2) Pub Date : 2024-03-20 Jan-Niklas Eckardt, Waldemar Hahn, Christoph Röllig, Sebastian Stasik, Uwe Platzbecker, Carsten Müller-Tidow, Hubert Serve, Claudia D. Baldus, Christoph Schliemann, Kerstin Schäfer-Eckart, Maher Hanoun, Martin Kaufmann, Andreas Burchert, Christian Thiede, Johannes Schetelig, Martin Sedlmayr, Martin Bornhäuser, Markus Wolfien, Jan Moritz Middeke
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Use of automated conversational agents in improving young population mental health: a scoping review npj Digit. Med. (IF 15.2) Pub Date : 2024-03-19 Raluca Balan, Anca Dobrean, Costina R. Poetar
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Can we learn from an imagined ransomware attack on a hospital at home platform? npj Digit. Med. (IF 15.2) Pub Date : 2024-03-20 Stephen Gilbert, Francesco Ricciardi, Tauseef Mehrali, Constantinos Patsakis
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Dynamic associations between glucose and ecological momentary cognition in Type 1 Diabetes npj Digit. Med. (IF 15.2) Pub Date : 2024-03-18 Z. W. Hawks, E. D. Beck, L. Jung, L. M. Fonseca, M. J. Sliwinski, R. S. Weinstock, E. Grinspoon, I. Xu, R. W. Strong, S. Singh, H. P. A. Van Dongen, M. R. Frumkin, J. Bulger, M. J. Cleveland, K. Janess, Y. C. Kudva, R. Pratley, M. R. Rickels, S. R. Rizvi, N. S. Chaytor, L. T. Germine
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Evaluating reliability in wearable devices for sleep staging npj Digit. Med. (IF 15.2) Pub Date : 2024-03-18 Vera Birrer, Mohamed Elgendi, Olivier Lambercy, Carlo Menon
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Effect of clinical decision support for severe hypercholesterolemia on low-density lipoprotein cholesterol levels npj Digit. Med. (IF 15.2) Pub Date : 2024-03-18 Hana Bangash, Seyedmohammad Saadatagah, Mohammadreza Naderian, Marwan E. Hamed, Lubna Alhalabi, Alborz Sherafati, Joseph Sutton, Omar Elsekaily, Ali Mir, Justin H. Gundelach, Daniel Gibbons, Paul Johnsen, Christina M. Wood-Wentz, Carin Y. Smith, Pedro J. Caraballo, Kent R. Bailey, Iftikhar J. Kullo
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Technology-supported behavior change interventions for reducing sodium intake in adults: a systematic review and meta-analysis npj Digit. Med. (IF 15.2) Pub Date : 2024-03-18 Yong Yang Yan, Lily Man Lee Chan, Man Ping Wang, Jojo Yan Yan Kwok, Craig S. Anderson, Jung Jae Lee
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An aligned framework of actively collected and passively monitored clinical outcome assessments (COAs) for measure selection npj Digit. Med. (IF 15.2) Pub Date : 2024-03-16 Christine Manta Campbell, Courtney Webster, Megan Parisi, Roya Sherafat-Kazemzadeh, Jessica Braid, Thomas Switzer, Marcelo Alves Fávaro, Caprice Sassano, Andrea Coravos
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Physical activity and sleep changes among children during the COVID-19 pandemic npj Digit. Med. (IF 15.2) Pub Date : 2024-03-16 Karnika Singh, Sarah C. Armstrong, Brooke E. Wagner, Julie Counts, Asheley Skinner, Melissa Kay, Jennifer S. Li, Svati Shah, Nancy Zucker, Cody Neshteruk, Mary Story, Lilianna Suarez, William E. Kraus, Alexandra R. Zizzi, Jessilyn Dunn
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The lucent yet opaque challenge of regulating artificial intelligence in radiology npj Digit. Med. (IF 15.2) Pub Date : 2024-03-15 James M. Hillis, Jacob J. Visser, Edward R. Scheffer Cliff, Kelly van der Geest – Aspers, Bernardo C. Bizzo, Keith J. Dreyer, Jeremias Adams-Prassl, Katherine P. Andriole
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Indigenous data governance approaches applied in research using routinely collected health data: a scoping review npj Digit. Med. (IF 15.2) Pub Date : 2024-03-15 Teyl Engstrom, Elton H. Lobo, Kristie Watego, Carmel Nelson, Jinxiang Wang, Howard Wong, Sungkyung Linda Kim, Soo In Oh, Michael Lawley, Alain-Dominique Gorse, James Ward, Clair Sullivan
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Informing immunotherapy with multi-omics driven machine learning npj Digit. Med. (IF 15.2) Pub Date : 2024-03-14 Yawei Li, Xin Wu, Deyu Fang, Yuan Luo