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The impact of, and expectations for, lipid nanoparticle technology: From cellular targeting to organelle targeting J. Control. Release (IF 10.8) Pub Date : 2024-05-09 Yusuke Sato, Takashi Nakamura, Yuma Yamada, Hideyoshi Harashima
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An ultrasound-activated nanoplatform remodels tumor microenvironment through diverse cell death induction for improved immunotherapy J. Control. Release (IF 10.8) Pub Date : 2024-05-09 Jingbo Ma, Haitao Yuan, Jingjing Zhang, Xin Sun, Letai Yi, Weihua Li, Zhifen Li, Chunjin Fu, Liuhai Zheng, Xiaolong Xu, Xiaoxian Wang, Fujing Wang, Da Yin, Jimin Yuan, Chengchao Xu, Zhijie Li, Xin Peng, Jigang Wang
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Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation. J. Control. Release (IF 10.8) Pub Date : 2024-05-08 Jie Zhang, Vitalina Bodenko, Maria Larkina, Ekaterina Bezverkhniaia, Tianqi Xu, Yunqi Liao, Ayman Abouzayed, Evgenii Plotnikov, Maria Tretyakova, Feruza Yuldasheva, Mikhail V. Belousov, Anna Orlova, Vladimir Tolmachev, Torbjörn Gräslund, Anzhelika Vorobyeva
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Multidimensional opioid abuse deterrence using a nanoparticle-polymer hybrid formulation J. Control. Release (IF 10.8) Pub Date : 2024-05-08 Sheryhan F. Gad, Anastasiia Vasiukhina, Joseph S. Keller, Luis Solorio, Yoon Yeo
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Knocking down of Xkr8 enhances chemotherapy efficacy through modulating tumor immune microenvironment J. Control. Release (IF 10.8) Pub Date : 2024-05-08 Yuang Chen, Chien-Yu Chen, Haozhe Huang, Zhangyi Luo, Yiqing Mu, Shichen Li, Yixian Huang, Song Li
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Cell selective BCL-2 inhibition enabled by lipid nanoparticles alleviates lung fibrosis J. Control. Release (IF 10.8) Pub Date : 2024-05-06 Rimpy Diwan, Himanshu N. Bhatt, Rui Dong, Igor L. Estevao, Armando Varela-Ramirez, Md Nurunnabi
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Biodegradable pyroptosis inducer with multienzyme-mimic activity kicks up reactive oxygen species storm for sensitizing immunotherapy J. Control. Release (IF 10.8) Pub Date : 2024-05-06 Junrong Wang, Luying Qiao, Guoqing Zhu, Qianqian Sun, Yulin Xie, Man Wang, Yaqi Xu, Chunxia Li
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Long-term combined blockade of CXCR4 and PD-L1 with in vivo reassembly for intensive tumor interference J. Control. Release (IF 10.8) Pub Date : 2024-05-06 Zhen-Wei Deng, Jian-Ke Yang, Kai-Jin Qiu, Ting-Jie Zhang, Zheng He, Na Wang, Xi-Guang Chen, Ya Liu
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Small extracellular vesicles of organoid-derived human retinal stem cells remodel Müller cell fate via miRNA: A novel remedy for retinal degeneration J. Control. Release (IF 10.8) Pub Date : 2024-05-05 Shudong Huang, Yuxiao Zeng, Qiang Guo, Ting Zou, Zheng Qin Yin
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UiO-66(Zr) as drug delivery system for non-steroidal anti-inflammatory drugs J. Control. Release (IF 10.8) Pub Date : 2024-05-05 Javier Salazar, Yoan Hidalgo-Rosa, Pia C. Burboa, Yi-nan Wu, Néstor Escalona, Angel Leiva, Ximena Zarate, Eduardo Schott
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Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria J. Control. Release (IF 10.8) Pub Date : 2024-05-04 Sofie Meulewaeter, Ilke Aernout, Joke Deprez, Yanou Engelen, Margo De Velder, Lorenzo Franceschini, Karine Breckpot, Serge Van Calenbergh, Caroline Asselman, Katie Boucher, Francis Impens, Stefaan C. De Smedt, Rein Verbeke, Ine Lentacker
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Metabolic dysfunction-associated steatohepatitis treated by poly(ethylene glycol)-block-poly(cysteine) block copolymer-based self-assembling antioxidant nanoparticles J. Control. Release (IF 10.8) Pub Date : 2024-05-03 Yuta Koda, Yukio Nagasaki
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Injectable hydrogel harnessing foreskin mesenchymal stem cell-derived extracellular vesicles for treatment of chronic diabetic skin wounds J. Control. Release (IF 10.8) Pub Date : 2024-05-03 Chang Xu, Jin-Feng Cao, Yue Pei, Yujin Kim, Huiyeon Moon, Chui-Qin Fan, Mao-Chuan Liao, Xing-Yu Wang, Fei Yao, Yu-Jun Zhang, Shao-Hui Zhang, Jian Zhang, Jian-Zhang Li, Jong Seung Kim, Lian Ma, Zhong-Jian Xie
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Metal coordination nanotheranostics mediated by nucleoside metabolic inhibitors potentiate STING pathway activation for cancer metalloimmunotherapy J. Control. Release (IF 10.8) Pub Date : 2024-05-03 Lianyi Yang, Yazhen Wang, Yujun Song, Zeya Li, Lei Lei, Hanmei Li, Bin He, Jun Cao, Huile Gao
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Biomaterials-mediated radiation-induced diseases treatment and radiation protection J. Control. Release (IF 10.8) Pub Date : 2024-05-02 Jianping Man, Yanhua Shen, Yujie Song, Kai Yang, Pei Pei, Lin Hu
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Oral targeted drug delivery to post-gastrointestinal sites J. Control. Release (IF 10.8) Pub Date : 2024-05-01 Rongze Han, Haisheng He, Yi Lu, Huiping Lu, Shun Shen, Wei Wu
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Enhancing calvarial defects repair with PDGF-BB mimetic peptide hydrogels J. Control. Release (IF 10.8) Pub Date : 2024-05-01 Xia Wu, Mingming Yan, Jun Shen, Yatong Xiang, Ke Jian, Xiaoyun Pan, Dan Yuan, Junfeng Shi
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Biomaterial-based scaffolds for direct in situ programming of tumor-infiltrating T lymphocytes J. Control. Release (IF 10.8) Pub Date : 2024-05-01 V.V. Inamdar, S. Hao, S.B. Stephan, M.T. Stephan
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Emerging advances in delivery systems for mRNA cancer vaccines J. Control. Release (IF 10.8) Pub Date : 2024-05-01 Zhimei Jiang, Yanhua Xu, Guangsheng Du, Xun Sun
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Site-selective antibody-lipid conjugates for surface functionalization of red blood cells and targeted drug delivery J. Control. Release (IF 10.8) Pub Date : 2024-05-01 Biquan Li, Dingdong Yuan, Hongfei Chen, Xun Wang, Yujie Liang, Clarence T.T. Wong, Jiang Xia
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Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose J. Control. Release (IF 10.8) Pub Date : 2024-04-27 Janin Germer, Anna-Lina Lessl, Jana Pöhmerer, Melina Grau, Eric Weidinger, Miriam Höhn, Mina Yazdi, Martino Alfredo Cappelluti, Angelo Lombardo, Ulrich Lächelt, Ernst Wagner
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Healing with precision: A multi-functional hydrogel-bioactive glass dressing boosts infected wound recovery and enhances neurogenesis in the wound bed J. Control. Release (IF 10.8) Pub Date : 2024-04-27 Yu Kang, Kun Liu, Zhenbing Chen, Jiahe Guo, Kaituo Xiang, Xiaopei Wu, Tao Jiang, Jing Chen, Chenqi Yan, Guoyong Jiang, Yufeng Wang, Maojie Zhang, Xuejiao Xiang, Honglian Dai, Xiaofan Yang
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A facile and smart strategy to enhance bone regeneration with efficient vitamin D3 delivery through sterosome technology J. Control. Release (IF 10.8) Pub Date : 2024-04-25 Shuxi Ye, Jing Wen, Wen-Hao Ye, Zhen Li, Xiaomeng Huang, Sixu Chen, Jian-Chao Ma, Yaohong Wu, Rongchun Chen, Zhong-Kai Cui
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Integrated anti-vascular and immune-chemotherapy for colorectal carcinoma using a pH-responsive polymeric delivery system J. Control. Release (IF 10.8) Pub Date : 2024-04-25 Xiaoqian Ma, Qing Yang, Nuo Lin, Yushuo Feng, Yaqing Liu, Peifei Liu, Yiru Wang, Huaping Deng, Haizhen Ding, Hongmin Chen
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Enhanced oral and pulmonary delivery of biomacromolecules via amplified transporter targeting J. Control. Release (IF 10.8) Pub Date : 2024-04-25 Xin Xiao, Lie Zhang, Mingjie Ni, Xi Liu, Liyun Xing, Licheng Wu, Zhou Zhou, Lian Li, Jingyuan Wen, Yuan Huang
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Can in vitro/in silico tools improve colonic concentration estimations for oral extended-release formulations? A case study with upadacitinib J. Control. Release (IF 10.8) Pub Date : 2024-04-25 Alessia Favaron, Bart Hens, Maiara Camotti Montanha, Mark McAllister, Irena Tomaszewska, Shaimaa Moustafa, Marília Alvarenga de Oliveira, Abdul W. Basit, Mine Orlu
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Particulate bioaerogels for respiratory drug delivery J. Control. Release (IF 10.8) Pub Date : 2024-04-25 Hao-Ying Li, Charalampos Makatsoris, Ben Forbes
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Hybrid adipocyte-derived exosome nano platform for potent chemo-phototherapy in targeted hepatocellular carcinoma J. Control. Release (IF 10.8) Pub Date : 2024-04-24 Xinying Liu, Jiaxin Zhang, Shunzhe Zheng, Meng Li, Wenqian Xu, Jianbin Shi, Ken-ichiro Kamei, Chutong Tian
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Tailoring drug release from long-acting contraceptive levonorgestrel intrauterine systems J. Control. Release (IF 10.8) Pub Date : 2024-04-24 Suraj Fanse, Quanying Bao, Yuan Zou, Yan Wang, Diane J. Burgess
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Positron emission tomography guided synergistic treatment of melanoma using multifunctional zirconium-hematoporphyrin nanosonosensitizers J. Control. Release (IF 10.8) Pub Date : 2024-04-23 Xiaodan Jiao, Xiaoyang Li, Yan Du, Yiyang Cong, Shuyang Yang, Daiqin Chen, Tao Zhang, Min Feng, Hao Hong
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Superior COL7A1 and TGM1 gene expression in difficult-to-transfect skin cell mediated by highly branched poly(β-amino esters) through stepwise fractionation J. Control. Release (IF 10.8) Pub Date : 2024-04-23 Chaolan Pan, Chenfei Wang, Yitong Zhao, Tao Bo, Liping Han, Dingjin Yao, Yumeng Wang, Xiaoxiao Wang, Linjing Shi, Anqi Zhao, Qiaoyu Cao, Fuying Chen, Wei He, Ying Ye, Si Zhang, Ming Li
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Cadherin-11 targeted cell-specific liposomes enabled skin fibrosis treatment by inducing apoptosis J. Control. Release (IF 10.8) Pub Date : 2024-04-23 Himanshu N. Bhatt, Rimpy Diwan, Igor L. Estevao, Rui Dong, Jennifer Smith, Chuan Xiao, Sandeep K. Agarwal, Md Nurunnabi
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Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting J. Control. Release (IF 10.8) Pub Date : 2024-04-18 Wenjie Ma, Di Wu, Chengcheng Long, Jingyu Liu, Luwei Xu, Liuhua Zhou, Quanliang Dou, Yuzheng Ge, Changcheng Zhou, Ruipeng Jia
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Barcode lipids for absolute quantitation of liposomes in ocular tissues J. Control. Release (IF 10.8) Pub Date : 2024-04-17 Arto Merivaara, Jooseppi Puranen, Amir Sadeghi, Natalia Zashikhina, Lea Pirskanen, Tatu Lajunen, Tetsuya Terasaki, Seppo Auriola, Kati-Sisko Vellonen, Arto Urtti
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Nanodrugs based on co-delivery strategies to combat cisplatin resistance J. Control. Release (IF 10.8) Pub Date : 2024-04-17 Qiubo Wang, Hui Li, Taixia Wu, Bing Yu, Hailin Cong, Youqing Shen
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Recent progress on engineered micro/nanomaterials mediated modulation of gut microbiota for treating inflammatory bowel disease J. Control. Release (IF 10.8) Pub Date : 2024-04-17 Lingling Kan, Ziwen Zheng, Wanyue Fu, Yan Ma, Wanni Wang, Haisheng Qian, Lingling Xu
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Remotely controlled drug release in deep brain regions of non-human primates J. Control. Release (IF 10.8) Pub Date : 2024-04-17 Matthew G. Wilson, Taylor D. Webb, Henrik Odéen, Jan Kubanek
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Hybrid biomineralized nanovesicles to enhance inflamed lung biodistribution and reduce side effect of glucocorticoid for ARDS therapy J. Control. Release (IF 10.8) Pub Date : 2024-04-15 Qi Qiao, Xiaonan Li, Xiangjun Ou, Xiong Liu, Chuansheng Fu, Yi Wang, Boning Niu, Li Kong, Conglian Yang, Zhiping Zhang
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mRNA-responsive two-in-one nanodrug for enhanced anti-tumor chemo-gene therapy J. Control. Release (IF 10.8) Pub Date : 2024-04-15 Yongfei Liu, Yuhong Lin, Han Xiao, Zhangcheng Fu, Xiaohui Zhu, Xiaoyong Chen, Chunsen Li, Chenyu Ding, Chunhua Lu
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Cardiac delivery of modified mRNA using lipid nanoparticles: Cellular targets and biodistribution after intramyocardial administration J. Control. Release (IF 10.8) Pub Date : 2024-04-13 M.C.I. Labonia, M. Estapé Senti, P.H. van der Kraak, M.A.D. Brans, I. Dokter, T.J. Streef, A.M. Smits, A.K. Deshantri, S.C.A. de Jager, R.M. Schiffelers, J.P.G. Sluijter, P. Vader
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A novel peptide-drug conjugate for glioma-targeted drug delivery J. Control. Release (IF 10.8) Pub Date : 2024-04-13 Jianfen Zhou, Nana Meng, Linwei Lu, Jiasheng Lu, Sunyi Wu, Yuan Ding, Shuai Wu, Yanning Bao, Qianzhu Xu, Ruohan Chen, Jun Wang, Cao Xie, Jinsong Wu, Weiyue Lu
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mRNA therapies: Pioneering a new era in rare genetic disease treatment J. Control. Release (IF 10.8) Pub Date : 2024-04-13 Guobo Shen, Jian Liu, Hanmei Yang, Na Xie, Yang Yang
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The predominant Quillaja Saponaria fraction, QS-18, is safe and effective when formulated in a liposomal murine cancer peptide vaccine J. Control. Release (IF 10.8) Pub Date : 2024-04-12 Shiqi Zhou, Yiting Song, Anoop Nilam, Yuan Luo, Wei-Chiao Huang, Mark D. Long, Jonathan F. Lovell
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Drug and nucleic acid delivery and targeting to the brain J. Control. Release (IF 10.8) Pub Date : 2024-04-12 Deepak Chitkara, Ram I. Mahato
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Enhancing SN38 prodrug delivery using a self-immolative linker and endogenous albumin transport J. Control. Release (IF 10.8) Pub Date : 2024-04-11 Xing Jiang, Lingyi Zhu, Qingyu Wei, Wei Lu, Jiahui Yu, Shulei Zhu
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Co-encapsulation of granzyme B and perforin in nanocapsules for tumour therapy: biomimicking immune cells J. Control. Release (IF 10.8) Pub Date : 2024-04-11 Zhendong Shi, Juanjuan Yan, Ming Zhao, Shanshan Li, Tiantian She, Xiaomin Qian
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The colon targeting efficacies of mesalazine medications and their impacts on the gut microbiome J. Control. Release (IF 10.8) Pub Date : 2024-04-11 Laura E. McCoubrey, Nidhi Seegobin, Nannapat Sangfuang, Frédéric Moens, Hans Duyvejonck, Eline Declerck, Arno Dierick, Massimo Marzorati, Abdul W. Basit
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A blood–brain barrier- and blood–brain tumor barrier-penetrating siRNA delivery system targeting gliomas for brain tumor immunotherapy J. Control. Release (IF 10.8) Pub Date : 2024-04-11 Lin Tang, Rui Zhang, Yusi Wang, Mohan Liu, Die Hu, Yefeng Wang, Li Yang
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Strategic aspects for the commercialization of nanomedicines J. Control. Release (IF 10.8) Pub Date : 2024-04-11 Eva Hemmrich, Scott McNeil
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Continuous iontronic chemotherapy reduces brain tumor growth in embryonic avian in vivo models J. Control. Release (IF 10.8) Pub Date : 2024-04-11 Verena Handl, Linda Waldherr, Theresia Arbring Sjöström, Tobias Abrahamsson, Maria Seitanidou, Sabine Erschen, Astrid Gorischek, Iwona Bernacka-Wojcik, Helena Saarela, Tamara Tomin, Sophie Elisabeth Honeder, Joachim Distl, Waltraud Huber, Martin Asslaber, Ruth Birner-Grünberger, Ute Schäfer, Magnus Berggren, Rainer Schindl, Silke Patz, Daniel T. Simon, Nassim Ghaffari-Tabrizi-Wizsy
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An injectable sequential dual-crosslinking catechol-functionalized hyaluronic acid hydrogel for enhanced regeneration of full-thickness burn injury J. Control. Release (IF 10.8) Pub Date : 2024-04-10 Wenning Zhang, Shuo Zhang, Tianyu Zhao, Hong Zhang
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An injectable thermoresponsive-hydrogel for lamellar keratoplasty: In-situ releases celastrol and hampers corneal scars J. Control. Release (IF 10.8) Pub Date : 2024-04-10 Zhanrong Li, Ruixing Liu, Xiacong Zhang, Zhihua Guo, Xingchen Geng, Dandan Chu, Haohao Cui, Afang Zhang, Wen Li, Lei Zhu, Jingguo Li
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Self-adjuvanting polymeric nanovaccines enhance IFN production and cytotoxic T cell response J. Control. Release (IF 10.8) Pub Date : 2024-04-10 Ming Zhao, Chunting He, Xueyun Zheng, Min Jiang, Zhiqiang Xie, Hongjiao Wei, Shujun Zhang, Ying Lin, Jiaheng Zhang, Xun Sun
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ROS-responsive sprayable hydrogel as ROS scavenger and GATA6+ macrophages trap for the prevention of postoperative abdominal adhesions J. Control. Release (IF 10.8) Pub Date : 2024-04-10 Yanjuan Huang, Xiuling Dai, Yujun Gong, Lingling Ren, Yong Luo, Yue Sun, Meixu Chen, Jingwen Jiang, Zilin Guan, Chunshun Zhao
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Remodeling brain pathological microenvironment to lessen cerebral ischemia injury by multifunctional injectable hydrogels J. Control. Release (IF 10.8) Pub Date : 2024-04-10 Wen Zhang, Yang Liu, Zhicun Wang, Shuyi He, Wenqi Liu, Yu Wu, Li Yang, Cheng Hu, Yunbing Wang
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Nuclear-targeted chimeric peptide nanorods to amplify innate anti-tumor immunity through localized DNA damage and STING activation J. Control. Release (IF 10.8) Pub Date : 2024-04-09 Yeyang Wu, Yanmei Li, Ni Yan, Jiaqi Huang, Xinyu Li, Keyan Zhang, Zhenming Lu, Ziwen Qiu, Hong Cheng
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Enhanced capillary delivery with nanobubble-mediated blood-brain barrier opening and advanced high resolution vascular segmentation J. Control. Release (IF 10.8) Pub Date : 2024-04-08 Roni Gattegno, Lilach Arbel, Noa Riess, Hila Shinar, Sharon Katz, Tali Ilovitsh
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Disrupting glycolysis and DNA repair in anaplastic thyroid cancer with nucleus-targeting platinum nanoclusters J. Control. Release (IF 10.8) Pub Date : 2024-04-08 Zongfu Pan, Xixuan Lu, Xi Hu, Ruixi Yu, Yulu Che, Jie Wang, Lin Xiao, Jianqiang Chen, Xiaofen Yi, Zhuo Tan, Fangyuan Li, Daishun Ling, Ping Huang, Minghua Ge
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Surface functionalization of exosomes for chondrocyte-targeted siRNA delivery and cartilage regeneration J. Control. Release (IF 10.8) Pub Date : 2024-04-06 Hao Zhang, Wenjing Yan, Jinhui Wang, Shuqian Xie, W. Andy Tao, Chien-Wei Lee, Xing Zhang, Guiyuan Zhang, Yufeng Liu, Dong Wei, Jing Hu, Haohan Liu, Fengying Liu, Yamei Nie, Xue Chen, Hongtao Xu, Jiang Xia, Shizhi Wang
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Tumor-penetrating iRGD facilitates penetration of poly(floxuridine-ketal)-based nanomedicine for enhanced pancreatic cancer therapy J. Control. Release (IF 10.8) Pub Date : 2024-04-06 Xingwei Li, Haiping Zhong, Shujing Zheng, Jingqing Mu, Na Yu, Shutao Guo