样式: 排序: IF: - GO 导出 标记为已读
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Requiem for Urate Lowering in CKD? J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-04-10 David B. Mount
An abstract is unavailable.
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Equity in Preemptive Kidney Transplantation: The Case for Caution J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-04-08 Robert W. Steiner
An abstract is unavailable.
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Consent for High–Kidney Donor Profile Index Kidneys: The Responsibility of Transplant Centers to Get it Right J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-04-08 Peter Stock, Charles Gerard Rickert
An abstract is unavailable.
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Kidney Endothelial Cell Biology in Health and Disease J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-04-08 Sargis Sedrakyan
An abstract is unavailable.
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Renal Intercalated Cell Differentiation and Acid–Base Regulation J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-04-08 Carsten A. Wagner
An abstract is unavailable.
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A Requiem for Fistula First J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-04-01 Michael Allon, Timmy Lee
An abstract is unavailable.
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The Challenge of Assessing Remission and Relapse in ANCA Kidney Disease J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-13 Brix, Silke R.
No abstract available
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Secular Trends in Incidence of Treated Kidney Failure in the United States J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-13 Mallory L. Downie, Bethany J. Foster
An abstract is unavailable.
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Watering Collecting Duct Cysts: Are Aquaporin2+ Progenitors the Answer? J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-13 Mauricio Ostrosky-Frid, Vishal Patel
An abstract is unavailable.
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Posoleucel in Kidney Transplant Recipients with BK Viremia: Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-12 Anil Chandraker, Anil Regmi, Reginald Gohh, Akhil Sharma, E. Steve Woodle, Mohammed J. Ansari, Vinay Nair, Ling-Xin Chen, Tarek Alhamad, Silas Norman, Diane Cibrik, Manpreet Singh, Arnold Alper, Divya Jain, Ziad Zaky, Stuart Knechtle, Asif Sharfuddin, Gaurav Gupta, Bonnie E. Lonze, Jo-Anne H. Young, Deborah Adey, Arman Faravardeh, Darshana M. Dadhania, Ana P. Rossi, Diana Florescu, Francesca Cardarelli
rsistence of posoleucel was confirmed by T-cell receptor variable β sequencing. Background Kidney transplant recipients with BK virus infection are at risk of developing BK virus–associated nephropathy, allograft rejection, and subsequent graft loss. There are no approved treatments for BK virus infection. Posoleucel is an off-the-shelf, allogeneic, multivirus-specific T-cell investigational therapy
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Reduced Nephron Endowment in Six2-TGCtg Mice Is Due to Six3 Misexpression by Aberrant Enhancer–Promoter Interactions in the Transgene J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-06 Alison J. Perl, Han Liu, Matthew Hass, Nirpesh Adhikari, Praneet Chaturvedi, Yueh-Chiang Hu, Rulang Jiang, Yaping Liu, Raphael Kopan
long kidney function relies on the complement of nephrons generated during mammalian development from a mesenchymal nephron progenitor cell population. Low nephron endowment confers increased susceptibility to CKD. Reduced nephron numbers in the popular Six2TGC transgenic mouse line may be due to disruption of a regulatory gene at the integration site and/or ectopic expression of a gene(s) contained
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Authors' Reply: Eculizumab Seems to be a Life Saver Even in Shiga Toxin-Related Hemolytic Uremic Syndrome J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-01 Garnier, Arnaud
No abstract available
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Prioritizing Skills for Optimal Peritoneal Dialysis Care: A Focus Beyond Specialty J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-01 Sahutoglu, Tuncay
No abstract available
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Assessment of Novel Therapeutics to Improve Access to Transplantation for Highly Sensitized Patients in a Shifting Clinical Landscape J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-01 Lan, James H.
No abstract available
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Adenine Nucleotide Translocators Control Kidney Metabolism and Lipid Handling J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-01 Sugahara, Sho, Brooks, Craig R.
No abstract available
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Heterogeneity of Distal Convoluted Tubule Cells J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-01 Murillo-de-Ozores, Adrián R., Chen, Lihe
No abstract available
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Authors' Reply: Prioritizing Skills for Optimal Peritoneal Dialysis Care: A Focus Beyond Specialty J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-01 Ku, Elaine, McCulloch, Charles E., Copeland, Timothy P., Johansen, Kirsten L.
No abstract available
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Eculizumab Seems to be a Life Saver Even in Shiga Toxin–Related Hemolytic–Uremic Syndrome J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-03-01 Pottokaran, Jaicy
No abstract available
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Retraction: GQ5 Hinders Renal Fibrosis in Obstructive Nephropathy by Selectively Inhibiting TGF-β–Induced Smad3 Phosphorylation J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-27
No abstract available
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Daprodustat and Heart Failure in CKD J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-22 Jonathan W. Cunningham, Brian L. Claggett, Renato D. Lopes, John J.V. McMurray, Vlado Perkovic, Kevin Carroll, Thomas Hiemstra, Kaivan Khavandi, Mary Ann Lukas, Prerna Ranganathan, Jennifer Shannon, Janet van Adelsberg, Ajay K. Singh, Scott D. Solomon
rt failure. The hypoxia-inducible factor prolyl hydroxylase inhibitor daprodustat is an orally acting alternative to conventional injectable erythropoietin-stimulating agents (ESAs) for the treatment of anemia in patients with CKD. Whether daprodustat affects the risk of heart failure hospitalization is unknown. Methods The Anemia Studies in Chronic Kidney Disease: Erythropoiesis via a Novel Prolyl
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Combination Treatment with Verinurad and Allopurinol in CKD: A Randomized Placebo and Active Controlled Trial J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-20 Hiddo J.L. Heerspink, Austin G. Stack, Robert Terkeltaub, Niels Jongs, Lesley A. Inker, Magnus Bjursell, Noha Maklad, Shira Perl, Olof Eklund, Tord Rikte, C. David Sjöström, Vlado Perkovic, on behalf of the SAPPHIRE Investigators
t compared with allopurinol alone or placebo.Verinurad/allopurinol combination dose-dependently reduced serum urate concentrations compared with placebo. Background Hyperuricemia is associated with elevated risks of cardiovascular and chronic kidney disease (CKD). Since inhibition of urate transporter 1 has been suggested to be potentially nephroprotective, we performed a phase 2b study to assess
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Integrated Single-Cell Transcriptomic Atlas of Human Kidney Endothelial Cells J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-14 Ka Zhang, Hao Kan, Aiqin Mao, Fan Yu, Li Geng, Tingting Zhou, Lei Feng, Xin Ma
tions that support specific physiologic processes. However, the heterogeneity of human kidney endothelial cells has not yet been systematically described. Methods We reprocessed and integrated seven human kidney control single-cell/single-nucleus RNA sequencing datasets of >200,000 kidney cells in the same process. Results We identified five major cell types, 29,992 of which were endothelial cells
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Quantifying the Effect of Consent for High–Kidney Donor Profile Index Deceased Donor Transplants in the United States J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-13 Jesse D. Schold, Kendra D. Conzen, James Cooper, Susana Arrigain, Rocio Lopez, Sumit Mohan, Syed Ali Husain, Anne M. Huml, Peter T. Kennealey, Bruce Kaplan, Elizabeth A. Pomfret
for high-KDPI kidneys was associated with 15% higher adjusted rates of deceased donor transplantation. Background Despite known benefits of kidney transplantation, including transplantation from donors with increased risk factors, many waitlisted candidates die before transplantation. Consent to receive donor kidneys with lower expected survival (e.g., Kidney Donor Profile Index [KDPI] >85%) is typically
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Foxp1 Is Required for Renal Intercalated Cell Differentiation and Acid–Base Regulation J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-09 Shi-Ting Wu, Yu Feng, Renhua Song, Yanmiao Qi, Lin Li, Dongbo Lu, Yixuan Wang, Wenrun Wu, Angela Morgan, Xiaohong Wang, Yin Xia, Renjing Liu, Stephen I. Alexander, Justin Wong, Yuzhen Zhang, Xiangjian Zheng
e regulation. Background Kidney collecting ducts comprise principal cells and intercalated cells, with intercalated cells playing a crucial role in kidney acid–base regulation through H+ and HCO3− secretion. Despite its significance, the molecular mechanisms controlling intercalated cell development remain incompletely understood. Methods To investigate the specific role of Foxp1 in kidney tubular
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Single-Cell RNA Sequencing Identifies Response of Renal Lymphatic Endothelial Cells to Acute Kidney Injury J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-07 Heidi A. Creed, Saranya Kannan, Brittany L. Tate, David Godefroy, Priyanka Banerjee, Brett M. Mitchell, Ebba Brakenhielm, Sanjukta Chakraborty, Joseph M. Rutkowski
se renal lymphatic endothelial cells in quiescent and cisplatin-injured kidneys. Lymphatic endothelial cell gene expression changes were confirmed in ischemia–reperfusion injury and in cultured lymphatic endothelial cells, validating renal lymphatic endothelial cells single-cell RNA sequencing data. This study is the first to describe renal lymphatic endothelial cell heterogeneity and uncovers molecular
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Improving Community Care of Individuals with CKD J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-01 Lim, Cynthia Ciwei, Tay, Wei Yi
No abstract available
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Authors' Reply: Platelet Count, Platelet Volume and CKD J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-01 Kore, Rajshekhar, Jadvani, Dharmik, Arthur, John M., Jain, Nishank
No abstract available
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Cardiovascular-Kidney-Metabolic Health Syndrome: What Does the American Heart Association Framework Mean for Nephrology? J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-06 Nisha Bansal, Daniel Weiner, Mark Sarnak
An abstract is unavailable.
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The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal Tubular Function J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-06 Betül Haykir, Seraina Olivia Moser, Eva Maria Pastor-Arroyo, Udo Schnitzbauer, Zsuzsa Radvanyi, Isabel Prucker, Danye Qiu, Dorothea Fiedler, Adolfo Saiardi, Henning J. Jessen, Nati Hernando, Carsten A. Wagner
tasis is mostly unknown. We demonstrate in a renal cell line and in mice that Ip6k1 and Ip6k2 are critical for normal expression and function of the major renal Na+/Pi transporters NaPi-IIa and NaPi-IIc. Moreover, Ip6k1/2−/− mice also show symptoms of more generalized kidney dysfunction. Thus, our results suggest that IP6Ks are essential for phosphate metabolism and proper kidney function in mammals
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Platelet Count, Platelet Volume, and CKD J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-02-01 Daungsupawong, Hinpetch, Wiwanitkit, Viroj
No abstract available
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Age- and Race-Specific Changes in ESKD Incidence over Four Decades J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-30 Chyng-Wen Fwu, Paul W. Eggers, Jenna M. Norton, Debbie S. Gipson, Paul L. Kimmel, Ivonne H. Schulman, Kevin E. Chan, Kara Bennett, Susan R. Mendley
decades beginning in 1980. Growth in incidence slowed for most groups by 1993, and by 2006, the annual percent change (APC) in ESKD incidence had declined for all groups, except White adults, for whom rates continued to rise. By 2019, ESKD incidence among Black and White adolescents nearly returned to 1980 levels, but no other group achieved that degree of improvement. Nonetheless, the ESKD incidence
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Allocation and Utilization Patterns of Deceased Donor Kidneys for Preemptive Transplantation in the United States J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-29 Kristen L. King, Miko Yu, Anne M. Huml, Jesse D. Schold, Syed Ali Husain, Sumit Mohan
An abstract is unavailable.
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Update on Hemodialysis-Induced Multiorgan Ischemia: Brains and Beyond J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-26 Christopher W. McIntyre
ion, abnormal perfusion to critical organs (heart, brain, liver, and kidney), and damage to vulnerable vascular beds. Recurrent conventional hemodialysis exposes patients to multiple episodes of circulatory stress, exacerbating and being aggravated by microvascular endothelial dysfunction. This promulgates progressive injury that leads to irreversible multiorgan injury and the well-documented higher
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Prophylactic Phosphate Restriction: A Strategy to Mitigate AKI-Associated Complications J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-26 Ben-Dov, Iddo Z., Potruch, Assaf, Abbasi, Momen
No abstract available
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Amiloride Reduces Urokinase/Plasminogen-Driven Intratubular Complement Activation in Glomerular Proteinuria J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-23 Gustaf L. Isaksson, Gitte R. Hinrichs, Henrik Andersen, Marie L. Bach, Kathrin Weyer, Rikke Zachar, Jan Erik Henriksen, Kirsten Madsen, Ida K. Lund, Géraldine Mollet, Claus Bistrup, Henrik Birn, Boye L. Jensen, Yaseelan Palarasah
lement and generates C3a and C5a in vitro/ex vivo in urine from healthy persons when exogenous, inactive, plasminogen, and complement factors are added. Amiloride inhibits uPA and attenuates complement activation in vitro and in vivo. In conditional podocin knockout (KO) mice with severe proteinuria, blocking of uPA with monoclonal antibodies significantly reduces the urine excretion of C3a and C5a
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Pkd2 Deficiency in Embryonic Aqp2+ Progenitor Cells Is Sufficient to Cause Severe Polycystic Kidney Disease J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-23 Akaki Tsilosani, Chao Gao, Enuo Chen, Andrea R. Lightle, Sana Shehzad, Madhulika Sharma, Pamela V. Tran, Carlton M. Bates, Darren P. Wallace, Wenzheng Zhang
emonstrating that Pkd2 deletion in embryonic Aqp2+ progenitor cells (AP), but not in neonate or adult Aqp2+ cells, is sufficient to cause severe polycystic kidney disease (PKD) with progressive loss of intercalated cells and complete elimination of α-intercalated cells, accurately recapitulating a newly identified cellular phenotype of patients with ADPKD. Hence, Pkd2 is a new potential regulator critical
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VALOR-CKD: A Multicenter, Randomized, Double-Blind Placebo-Controlled Trial Evaluating Veverimer in Slowing Progression of CKD in Patients with Metabolic Acidosis J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-23 Navdeep Tangri, Vandana S. Mathur, David A. Bushinsky, Gerrit Klaerner, Elizabeth Li, Dawn Parsell, Yuri Stasiv, Michael Walker, Donald E. Wesson, David C. Wheeler, Vlado Perkovic, Lesley A. Inker
CKD study randomized 1480 individuals with CKD and metabolic acidosis, across 320 sites to placebo or veverimer (a novel hydrochloric acid binder). The findings did not demonstrate the efficacy of veverimer in slowing CKD progression, but the difference in serum bicarbonate between placebo and drug arms was only approximately 1 mEq/L. Veverimer was safe and well tolerated. Background Metabolic acidosis
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Role of Age and Competing Risk of Death in the Racial Disparity of Kidney Failure Incidence after Onset of CKD J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-23 Guofen Yan, Robert Nee, Julia J. Scialla, Tom Greene, Wei Yu, Fei Heng, Alfred K. Cheung, Keith C. Norris
rans had a 2.5-fold higher cumulative incidence of kidney failure, compared with White veterans, in any follow-up period from CKD onset. This disparity resulted from a combination of higher hazards of progression to kidney failure and lower hazards of competing-risk death in Black veterans. Both, in turn, were largely explained by the younger age at CKD onset in Black veterans, underscoring an urgent
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cGAS Activation Accelerates the Progression of Autosomal Dominant Polycystic Kidney Disease J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-22 Miran Yoo, Jonathan C. Haydak, Evren U. Azeloglu, Kyung Lee, G. Luca Gusella
mechanistic link between the deficiency polycystin-1 and mitochondrial homeostasis and the activation of the cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS)/stimulator of the interferon genes (STING) pathway. Our data identify cGAS as an important mediator of renal cystogenesis and suggest that its inhibition may be useful to slow down the disease progression. Background Immune
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Enriched Single-Nucleus RNA-Sequencing Reveals Unique Attributes of Distal Convoluted Tubule Cells J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-19 Su, Xiao-Tong, Reyes, Jeremiah V., Lackey, Anne E., Demirci, Hasan, Bachmann, Sebastian, Maeoka, Yujiro, Cornelius, Ryan J., McCormick, James A., Yang, Chao-Ling, Jung, Hyun Jun, Welling, Paul A., Nelson, Jonathan W., Ellison, David H.
Significance Statement High-resolution single-nucleus RNA-sequencing data indicate a clear separation between primary sites of calcium and magnesium handling within distal convoluted tubule (DCT). Both DCT1 and DCT2 express Slc12a3, but these subsegments serve distinctive functions, with more abundant magnesium-handling genes along DCT1 and more calcium-handling genes along DCT2. The data also provide
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Urinary CD4+ T Cells Predict Renal Relapse in ANCA-Associated Vasculitis J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-17 Prskalo, Luka, Skopnik, Christopher M., Goerlich, Nina, Freund, Paul, Wagner, Leonie, Grothgar, Emil, Mirkheshti, Pouneh, Klocke, Jan, Sonnemann, Janis, Metzke, Diana, Schneider, Udo, Hiepe, Falk, Eckardt, Kai-Uwe, Salama, Alan D., Bieringer, Markus, Schreiber, Adrian, Enghard, Philipp
Significance Statement Early identification of patients at risk of renal flares in ANCA vasculitis is crucial. However, current clinical parameters have limitations in predicting renal relapse accurately. This study investigated the use of urinary CD4+ T lymphocytes as a predictive biomarker for renal flares in ANCA vasculitis. This study, including urine samples from 102 patients, found that the presence
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Resistant Hypertension in Dialysis: Epidemiology, Diagnosis, and Management J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-16 Panagiotis I. Georgianos, Rajiv Agarwal
ion, the prevalence of apparent treatment-resistant hypertension is estimated to be between 18% and 42%. Owing to the lack of a rigorous assessment of some common causes of pseudoresistance, the burden of true resistant hypertension in the dialysis population remains unknown. What distinguishes apparent treatment-resistance from true resistance is white-coat hypertension and adherence to medications
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Bridging the 13-Year Evidence Gap: A Time for Age-Inclusive Research J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-15 Oni, Louise, Smith, Rona, Salama, Alan D., Barratt, Jonathan, Trachtman, Howard, Saleem, Moin
No abstract available
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Insurance Transitions from Employer-Based Insurance to Medicare and Waitlisting for Kidney Transplantation: Placing Marietta v. DaVita in Context J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-15 Joel T. Adler, Arnold E. Kuk, David C. Cron, Layla Parast, Syed Ali Husain
An abstract is unavailable.
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Remembering Eberhard Ritz: A Clinician–Scientist Extraordinaire J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-11 Jochen Reiser, Martin Zeier
An abstract is unavailable.
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Renal Mitochondrial ATP Transporter Ablation Ameliorates Obesity-Induced CKD J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-11 Anna Permyakova, Sharleen Hamad, Liad Hinden, Saja Baraghithy, Aviram Kogot-Levin, Omri Yosef, Ori Shalev, Manish Kumar Tripathi, Haitham Amal, Abhishek Basu, Muhammad Arif, Resat Cinar, George Kunos, Michael Berger, Gil Leibowitz, Joseph Tam
y acid oxidation to aerobic glycolysis, resulting in mitochondrial protection, cellular survival, and preservation of renal function. These findings provide new insights into the underlying mechanisms of obesity-induced CKD and have the potential to be translated toward the development of targeted therapeutic strategies for this debilitating condition. Background The impairment in ATP production and
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Advancing Clinical Care through ASN Kidney Health Guidance J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-08 Sarah L. Sampsel, Deidra C. Crews
An abstract is unavailable.
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Lipid Management and Interactions with Immunosuppressants in Patients Undergoing Kidney Transplant: Opinions and Prospects J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-01 Li, Yanqin, Luo, Fan, Gao, Qi, Su, Licong
No abstract available
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Authors' Reply: Lipid Management and Interactions with Immunosuppressants in Kidney Transplant Patients: Some Opinions and Prospects J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-01 Bae, Sunjae, McAdams-DeMarco, Mara A.
No abstract available
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Phosphate Restriction Prevents Metabolic Acidosis and Curbs Rise in FGF23 and Mortality in Murine Folic Acid–Induced AKI J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2024-01-04 Ahmad Kamal Hamid, Eva Maria Pastor Arroyo, Charlotte Calvet, Timothy D. Hewitson, Maria Lavinia Muscalu, Udo Schnitzbauer, Edward R. Smith, Carsten Alexander Wagner, Daniela Egli-Spichtig
that dietary Pi restriction markedly diminished the early rise in plasma FGF23 and prevented the rise in plasma Pi, parathyroid hormone, and calcitriol in mice with folic acid–induced AKI (FA-AKI). Furthermore, the study provides evidence for Pi-sensitive osseous Fgf23 mRNA expression and reveals that Pi restriction mitigated calciprotein particles (CPPs) formation, inflammation, acidosis, cardiac
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Isatuximab Monotherapy for Desensitization in Highly Sensitized Patients Awaiting Kidney Transplant J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2023-12-26 Vincenti, Flavio, Bestard, Oriol, Brar, Amarpali, Cruzado, Josep M., Seron, Daniel, Gaber, A. Osama, Ali, Nicole, Tambur, Anat R., Lee, Helen, Abbadessa, Giovanni, Paul, Jo-Anne, Dudek, Markus, Siegel, Ruby J., Torija, Alba, Semiond, Dorothée, Lépine, Lucie, Ternes, Nils, Montgomery, Robert A., Stegall, Mark
Significance Statement There is no standardized desensitization regimen for kidney transplant candidates. CD38, expressed by plasma cells, could be targeted for desensitization to deplete plasma cells producing alloantibodies and donor-specific antibodies. Few studies and case reports are available regarding the use of CD38 antibodies for desensitization in patients awaiting kidney transplant. This
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SGLT2 Inhibition and Tubular Sodium Handling J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2023-12-22 Biff F. Palmer, Deborah J. Clegg
An abstract is unavailable.
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Are Observational Reports on the Association of Dialysate Sodium with Mortality Enough to Change Practice? Perspective from the RESOLVE Study Team J. Am. Soc. Nephrol. (IF 13.6) Pub Date : 2023-12-14 Brendan Smyth, Rathika Krishnasamy, Meg Jardine, on behalf of the RESOLVE Study Global Team
An abstract is unavailable.